Results 141 to 150 of about 44,475 (226)

Effects of imeglimin on experimental diabetic neuropathy in streptozotocin‐induced diabetic rats

Journal of Diabetes Investigation, Volume 17, Issue 6, Page 951-960, June 2026.
Imeglimin exerted neuroprotective effects in a type 1 diabetic neuropathy model, improving sensory nerve conduction, sciatic nerve blood flow, and intraepidermal nerve fiber density. In vitro, imeglimin promoted neurite outgrowth in a DRG‐derived hybridoma cell line, supporting a direct neurotrophic action.
Wataru Nihei, Ayako Kato, Takuma Sato, Masahiro Yamaguchi, Tatsuhito Himeno, Nobuhisa Nakamura, Kazunori Sango, Keiko Naruse, Jiro Nakamura, Hideki Kamiya, Koichi Kato   +10 more
wiley   +1 more source

<i>Trans</i>-Chalcone Reduces Inflammation and Pain Triggered by Superoxide Anion: Neuronal and Non-Neuronal Mechanisms. [PDF]

J Inflamm Res
Piva M, Manchope MF, Barbosa-Costa F, Bianchini BHS, Andrade KC, Silva LC, Calixto-Campos C, Rasquel-Oliveira FS, Fattori V, Zarpelon-Schutz AC, Camilios-Neto D, Borghi SM, Casagrande R, Verri WA.   +13 more
europepmc   +1 more source

Phenol Neurolysis in Pain and Palliative Medicine

Pain Practice, Volume 26, Issue 5, June 2026.
ABSTRACT Background Pain is a common symptom in palliative care and affects patients' quality of life considerably. Standard analgesics are sometimes insufficient and are associated with substantial side effects. Neurolysis, the targeted destruction of nerves using thermal or chemical agents, offers an additional option for managing localized pain in ...
Jeroen H. A. Creemers, Rachel J. H. Smits, Alopi M. Patel, Robert T. M. van Dongen, Cornelis K. Kramers, Jacqueline M. Bos, Selina E. I. van der Wal   +6 more
wiley   +1 more source

Protectin DX reduces inflammatory pain initiated by superoxide anion in mice: targeting leukocyte recruitment, oxidative stress, cytokine production and TRPV1⁺ nociceptive sensory neuron activation. [PDF]

Inflamm Res
Carneiro JA, Bianchini BHS, Martelossi-Cebinelli G, Artero NA, Maximiano TKE, Franciosi A, Dionisio AM, Yaekashi KM, Carvalho TT, da Silva MDV, Rasquel-Oliveira FS, Zanoveli JM, Fattori V, Casagrande R, Verri WA.   +14 more
europepmc   +1 more source

Voltage-gated sodium channel 1.8 contributes to hyperalgesia induced by the coexistence of anxiety and remifentanil exposure. [PDF]

Korean J Pain
Cai J, Chen L, Wang Y, Ye J, Xu Z, Gao L, Zhou Z, Sun J.   +7 more
europepmc   +1 more source

Evaluating FABP5 as a Therapeutic Target for Pain Management. [PDF]

Eur J Pain
Warren W, Osborn M, Kaczocha M, Yates A, O'Sullivan S.   +4 more
europepmc   +1 more source

Diosmetin as an Effective Treatment for Cisplatin-Induced Neuropathic Pain in Mice which does not Cause Hepatic or Renal Biomarker Alterations. [PDF]

Mol Neurobiol
Serafini PT, Dias R, Atuati SF, Oliveira SM.   +3 more
europepmc   +1 more source

The nociceptor primary cilium. [PDF]

Brain
Ganter GK, Reveche HC, Fitzsimons LA, Khomula EV, Levine JD, Tucker KL.   +5 more
europepmc   +1 more source

Synaptic Plasticity as a Mechanism of Opioid Tolerance and Hyperalgesia. [PDF]

Biology (Basel)
Qin F, Wang Q, Abdi S, Li L.
europepmc   +1 more source

The analgesic effect of neuropeptide S (NPS) in alcohol-dependent male and female rats. [PDF]

Alcohol
Marendes J, Young CL, Tunstall BJ.
europepmc   +1 more source