Results 131 to 140 of about 16,227 (258)

The pathophysiology of UVA-light induced hyperalgesia [PDF]

, 2009
D.Phil. Faculty of Health Sciences, University of the Witwatersrand, 2009In this thesis I describe the development of an animal model of sustained hyperalgesia induced by exposure to ultraviolet (UV) A light to the rat’s tail, and the role of the Cfibre
Themistocleus, Andreas Constantinos
core  

Peripheral and central mechanisms of NGF-induced hyperalgesia

, 1994
Mechanisms underlying the hyperalgesia induced by a single systemic injection of nerve growth factor (NGF) in adult rats were studied in vivo. A single dose of NGF initiated a prolonged thermal hyperalgesia to a radiant heat source within minutes that ...
Mendell, L.M., Alain Rueff, Gary R. Lewin, Rueff, A., Lewin, G.R., Lorne M. Mendell   +5 more
core   +1 more source

Bridging gaps in diabetic neuropathy care: A Delphi‐based regional consensus from the Gulf Cooperation Council

Journal of Diabetes Investigation, EarlyView.
A three‐round Delphi consensus developed GCC‐specific, evidence‐based recommendations for diabetic peripheral neuropathy (DPN) and painful diabetic neuropathy (PND). The consensus emphasizes proactive screening, early multimodal management, and addressing regional barriers to improve early detection, optimize management, and enhance quality of life ...
Abdulrahman Alshaikh, Abdulnabi T Alattar, Ahmed Abdul Karim Hassoun, Afaf Alshammary, Hussein Elbadawi, Khaled Aldossari, Noor Al Busaidi, Saud Alsifri, Talal Muzaffar, Wiam I. Hussein, Christine Talaat, Abanoub Effat, Marwa Elsaghier, Rayaz A Malik   +13 more
wiley   +1 more source

Effects of Aerobic Exercise and Strength Training on Nociplastic Pain and Clinical Features in Temporomandibular Disorders With Myalgia: A Randomized‐Controlled Trial

Journal of Oral Rehabilitation, EarlyView.
In this randomized controlled trial, adding aerobic exercise or strength training to physical therapy improved outcomes in patients with temporomandibular disorders and nociplastic pain. Aerobic exercise produced greater reductions in pain and central sensitization‐related symptoms, whereas strength training improved trapezius muscle strength and long ...
Flora Dantony, Daniel Romero‐Rodríguez, David Blanco, Carlos Antonio Zárate‐Tejero, Carolina Climent‐Sanz, Cristina Pérez‐Mánen, Andrea Màcia‐Martí, Natalia Felipe‐Spada, Andoni Carrasco‐Uribarren   +8 more
wiley   +1 more source

Electrophysiological characterisation of neuronal components of cold sensitivity [PDF]

, 2015
Aberrant cold sensitivity is apparent in several neuropathies of peripheral and central origin, and is poorly treated by currently available drugs.
Patel, R
core  

Effects of Clenching Intensity and Duration on Pressure Pain Threshold and Masseter‐Muscle Stiffness Under Standardised EMG‐Based Contraction Exposure

Journal of Oral Rehabilitation, EarlyView.
Under equivalent prescribed EMG‐based contraction exposure, pressure pain threshold was modestly but significantly lower immediately after low‐intensity, long‐duration clenching than after high‐intensity, short‐duration clenching, whereas the latter induced a transient reduction in masseter‐muscle stiffness.
Keisuke Miyazono, Hiroyuki Ishiyama, Akira Nishiyama, Kenji Fueki   +3 more
wiley   +1 more source

Effect of Remimazolam on Pain Perception and Opioid-Induced Hyperalgesia in Patients Undergoing Laparoscopic Urologic Surgery—A Prospective, Randomized, Controlled Study

Medicina
Background and Objectives: The effects of midazolam, a benzodiazepine, on pain perception are complex on both spinal and supraspinal levels. It is not yet known whether remimazolam clinically attenuates or worsens pain. The present study investigated the
Cheol Lee, Junsung Lim, Hansol Hong, Hyungjong Yu, Hayoung Lee   +4 more
doaj   +1 more source

Nitric oxide-dependent long-term potentiation revealed by real-time imaging of nitric oxide production and neuronal excitation in the dorsal horn of rat spinal cord slices

, 2006
Nitric oxide (NO) is thought to be involved in the central mechanism of hyperalgesia and allodynia at the spinal level. Recently, we reported that NO played an important role in the induction of long-term potentiation (LTP) of synaptic strength in spinal
MURASE, Kazuyuki, IKEDA, Hiroshi, KUSUDO, Kei   +2 more
core  

N‐methyl‐D‐aspartate receptor antagonists for controlling pain in dogs

Journal of Small Animal Practice, EarlyView.
This is a mini review published by the World Small Animal Veterinary Association's Pain Committee. This article provides an assessment of the scientific evidence of N‐methyl‐d‐aspartate receptor antagonists for controlling pain in dogs while identifying current knowledge gaps.
P. W. Kronen, B. D. X. Lascelles, B. P. Monteiro, J. C. Murrell, S. A. Robertson, P. V. Steagall, B. Wright   +6 more
wiley   +1 more source

Psychophysical changes after total sleep deprivation and experimental muscle pain

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Sleep disturbances exacerbate chronic pain, increase psychological load, and increase inflammation. Delayed onset muscle soreness (DOMS) mimics aspects of chronic pain, predominantly affecting peripheral pain mechanisms, while experimental sleep provocations have been shown to impact central pain mechanisms.
Emma Hertel, Elaxmi Sathiyalingam, Linea Pilgaard, Simone Juline Brommann, Rocco Giordano, Kristian Kjær‐Staal Petersen   +5 more
wiley   +1 more source