Results 151 to 160 of about 16,227 (258)
The Journal of Physiology, EarlyView.Abstract figure legend The regeneration of Aβ low‐threshold mechanoreceptors (Aβ‐LTMRs), sensory neurons responsible for discriminative touch, has not previously been explored. Here, we took advantage of the selective expression of Calb1 in Aβ‐LTMRs to generate two genetic mouse models for studying their regenerative response after nerve injury.
Sara Bolívar +3 more
wiley +1 more source
Incidence and Associated Factors for Chronic Pain After ICU Discharge: A Prospective Study
Nursing in Critical Care, Volume 31, Issue 6, November 2026.ABSTRACT Background Survivors of critical illness are at high risk for developing chronic pain. However, evidence regarding new‐onset chronic pain in this specific population remains limited in China. Aims This study aimed to investigate the incidence of chronic pain among Chinese intensive care unit (ICU) survivors at 3 months after discharge and to ...
Jinyu Yin +6 more
wiley +1 more source
POEMS Syndrome: 2026 Update on Diagnosis, Risk‐Stratification, and Management
American Journal of Hematology, Volume 101, Issue 10, Page 2632-2651, October 2026.ABSTRACT Disease Overview POEMS syndrome is a life‐threatening syndrome due to an underlying plasma cell neoplasm. The major criteria for the syndrome are polyneuropathy, clonal plasma cell disorder (PCD), sclerotic bone lesions, elevated vascular endothelial growth factor, and the presence of Castleman disease.
Angela Dispenzieri
wiley +1 more source
British Journal of Clinical Pharmacology, Volume 92, Issue 10, Page 3333-3353, October 2026.Chronic pain represents a complex debilitating condition that extends beyond the protective function of physiological pain, often persisting as an independent disease entity. Chronic primary and secondary pain syndromes reflect a multifaceted continuum involving nociceptive, neuropathic and nociplastic mechanisms.
Stefania Nobili +6 more
wiley +1 more source
Peripheral norepinephrine exacerbates neuritis-induced hyperalgesia.
, 2003 Inflammation of a peripheral nerve (neuritis) causes mechanical and thermal hyperalgesia in the region in which the inflamed nerve innervates. We investigated whether peripherally applied norepinephrine (NE) would exacerbate mechanical hyperalgesia in ...
Chung, JM, Chung, K, Baik, E
core +1 more source
European Journal of Pain, Volume 30, Issue 9, October 2026.ABSTRACT Background Pain and sensory disturbances are common non‐motor symptoms in Parkinson's disease (PD) and can occur early in the disease course, even before starting dopaminergic treatment. However, somatosensory abnormalities in drug‐naïve PD remain insufficiently characterized, particularly in the absence of dopaminergic medication effects ...
Maria Skallerup Andersen +5 more
wiley +1 more source
Postoperative hyperalgesia: Its clinical importance and relevance
, 2006 PAIN after surgery continues to be a major management challenge in clinical practice. In a recent meta-analysis covering some 20,000 patients and 800 publications, Dolin et al.
Ph.D Lars Arendt-Nielsen +2 more
core
Health Science Reports, Volume 9, Issue 10, October 2026.ABSTRACT Background and Aims In anesthesia and analgesia, opioids alone or in combination with local anesthetics (bupivacaine, lidocaine, and ropivacaine) have been investigated to prolong peripheral nerve blocks. Ultra‐low‐dose naloxone administration in local anesthetic solutions could lengthen sensory and motor blocks through enhanced opioid effects
Mohammadjavad Mehrabanian +7 more
wiley +1 more source
The role of nitric oxide in carrageenan-induced hyperalgesia /
, 1999 This thesis studied the role of spinal nitric oxide (NO) in carrageenan-induced dermal hyperalgesia in the rat hindpaw by means of intrathecal (i.t.) administration of various NO synthase (NOS) inhibitors.
Osborne, Michael G.
core
Pharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.From symptom relief to multimodal care: duloxetine and amitriptyline may reduce established CIPN‐related pain and provide a therapeutic foundation for future combination strategies. ABSTRACT Chemotherapy‐induced peripheral neuropathy (CIPN) is a prevalent and debilitating complication of cancer treatment, characterized by neuropathic pain, sensory ...
Rosamaria Caminiti +13 more
wiley +1 more source