Results 21 to 30 of about 8,334 (133)
JPGN Reports, EarlyView.Abstract Infantile exocrine pancreatic insufficiency is a rare condition, most often encountered in the context of cystic fibrosis or Shwachman–Diamond syndrome. The SPINK1 gene encodes a trypsin inhibitor protein that prevents the premature activation of digestive enzymes in pancreatic tissue.
France Chalon +10 more
wiley +1 more source
Journal of Gastroenterology and Hepatology, EarlyView.ABSTRACT Aim In hepatitis B surface antigen (HBsAg)‐negative recipients with antibody to hepatitis B core antigen (anti‐HBc)‐positive liver grafts, hepatitis B virus (HBV) can be reactivated under post‐transplant immunosuppression. We recently reported a median intrahepatic covalently closed circular DNA (cccDNA) level of 238 copies/μg in HBsAg ...
Sung Kwan Bae +15 more
wiley +1 more source
Transplant Infectious Disease, EarlyView.Doxycycline prophylaxis in lung transplant recipients was associated with reduced hyperammonemia syndrome and shorter ventilation, ICU, and hospital stays. These findings suggest that doxycycline prophylaxis may help prevent Ureaplasma/Mycoplasma‐related morbidity.
Lara Jones +6 more
wiley +1 more source
DEN Open, Volume 6, Issue 1, April 2026.ABSTRACT Duodenal varices, though rare, are potentially life‐threatening complications of portal hypertension. Management is challenging when balloon‐occluded retrograde transvenous obliteration (BRTO) fails to achieve complete obliteration. Endoscopic ultrasonography‐guided variceal therapy (EUS‐VT) is effective for gastric varices, but reports of ...
Sakue Masuda +6 more
wiley +1 more source
Hyperammonemia in Hepatic Encephalopathy [PDF]
Journal of Clinical and Experimental Hepatology, 2018 The precise mechanism underlying the neurotoxicity of Hepatic Encephalopathy (HE) is remains unclear. The dominant view has been that gut-derived nitrogenous toxins are not extracted by the diseased liver and thereby enter the brain. Among the various toxins proposed, the case for ammonia is most compelling.
A R, Jayakumar, Michael D, Norenberg
openaire +2 more sources
From the cytosol to the inner membrane: biogenesis of the mitochondrial carrier family
Protein Science, Volume 35, Issue 4, April 2026.Abstract Mitochondrial carrier proteins are essential for cellular physiology as they are active in a wide range of metabolic pathways including production of cellular energy, amino acid synthesis, redox balance and ion homeostasis. The double membrane of mitochondria provides a tightly gated environment through which carrier proteins facilitate the ...
Catherine S. Palmer +2 more
wiley +1 more source
Hyperammonemia in azotemic cats
Journal of Feline Medicine and Surgery, 2020 Objectives Hyperammonemia occurs in cats with hepatobiliary and nutritional (cobalamin and arginine deficiency) disorders, and has also been documented in four cats with renal azotemia. We hypothesized that in cats with renal azotemia, fasting hyperammonemia would correlate with indices of worsening kidney function, and would be independent of ...
Lauren Carvalho +3 more
openaire +2 more sources
Rising Inpatient Demands for Inherited Metabolic Disorders: Impact on Pediatric Capacity
American Journal of Medical Genetics Part A, EarlyView.
Maria Paula Silva +7 more
wiley +1 more source
Liver International, Volume 46, Issue 4, April 2026.ABSTRACT Background & Aims The efficacy of renal replacement therapy (RRT) in critically ill patients with cirrhosis remains dubious. We aimed to assess the impact of RRT on these patients' outcomes. Methods Multicenter retrospective cohort study including adult patients with cirrhosis admitted to intensive care units at University of Alberta Hospital (
Filipe S. Cardoso +5 more
wiley +1 more source