Results 1 to 10 of about 13,318 (166)

Prevalence of Prediabetes Risk in Offspring Born to Mothers with Hyperandrogenism

EBioMedicine, 2017
Background: Excessive androgen exposure during pregnancy has been suggested to induce diabetic phenotypes in offspring in animal models. The aim of this study was to investigate whether pregestational maternal hyperandrogenism in human influenced the ...
Xian-Hua Lin, Min Lv, Gu-feng Xu
exaly   +3 more sources

Rare Conditions of Hyperandrogenism Through Lifespan: A Case Series [PDF]

Case Reports in Endocrinology
A wide spectrum of clinical entities can lead to pre and postmenopausal hyperandrogenism, which is characterized by slow or more rapid onset of virilizing symptoms (menstrual irregularities, hirsutism, androgenetic alopecia).
Maria Apostolopoulou, Robert Taayedi, Cosmin Paul Sărac, Frank Demtröder   +3 more
doaj   +2 more sources

PPT1 regulation of HSP90α depalmitoylation participates in the pathogenesis of hyperandrogenism

iScience, 2023
Summary: Ovarian granulosa cells (GCs) in the follicle are the important mediator of steroidogenesis and foster oocyte maturation. Evidences suggested that the function of GCs could be regulated by S-palmitoylation.
Tongmin Xue, Shanmeizi Zhao, Hong Zhang, Ting Tang, Lu Zheng, Jun Jing, Xie Ge, Rujun Ma, Jinzhao Ma, Xiaoyan Ren, Kadiliya Jueraitetibaike, Zhigang Guo, Li Chen, Bing Yao   +13 more
doaj   +1 more source

Correlation between biochemical and clinical hyperandrogenism parameter in polycystic ovary syndrome in relation to age

BMC Endocrine Disorders, 2023
Background To assess the correlation between clinical and biochemical hyperandrogenism parameters in polycystic ovary syndrome (PCOS) according to age.
Zaixin Guo, Fengjun Jin, Shuwen Chen, Pan Hu, Yanfang Hao, Qi Yu   +5 more
doaj   +1 more source

Oxidative stress and antioxidant imbalance in ovulation disorder in patients with polycystic ovary syndrome

Frontiers in Nutrition, 2022
Polycystic ovary syndrome (PCOS) is a common reproductive endocrine disease that is characterized by oligo-ovulation or anovulation, hyperandrogenism, and polycystic ovaries observed using ultrasound with high clinical heterogeneity.
Wenqian Li, Chang Liu, Qingmei Yang, Ying Zhou, Min Liu, Hongying Shan, Hongying Shan   +6 more
doaj   +1 more source

Polycystic Ovarian Syndrome In Some Sample Of Iraqi Adolescents: Implementation Of Consensus Guidelines

مجلة الكوفة الطبية, 2023
Background: The diagnosis of polycystic ovarian syndrome (PCOS) in adolescent girls can be difficult because symptoms are shared with normal pubertal development.
Shymaa Khazaal Abid Jabok, Nada Abdulhor Al Ibrahimi   +1 more
doaj   +1 more source

Hyperandrogenism syndrome: diagnostics and treatment from the position of clinical endocrinology

Mìžnarodnij Endokrinologìčnij Žurnal, 2020
Hyperandrogenism, a pathological condition caused by the effect of excess production of androgens on target organs and tissues, is one of the most common hormonal disorders observed in 5–20 % of women of reproductive age in the population and in 35–41 ...
M.R. Mykytyuk, O.O. Khyzhnyak
doaj   +1 more source

Adrenal Hyperandrogenism in Children [PDF]

The Journal of Clinical Endocrinology & Metabolism, 1999
H of a mild-to-moderate degree is probably the most common abnormality in normoestrogenic menstrual disturbances. Androgen excess arises from abnormal ovarian or adrenal sources. The adrenal androgens, normally secreted by the fetal adrenal zone or the zona reticularis, are steroid hormones with weak androgen activity. Although adrenal androgens do not
GHIZZONI, Lucia, G. MASTORAKOS, A. VOTTERO   +2 more
openaire   +4 more sources

The Leydig Steroid Cell Tumor in a Postmenopausal Woman with Clinical and Biochemical Hyperandrogenism: A Case Report

Metabolites, 2022
Leydig cell tumors (LCTs) refer to tumors of the stroma of the genital strand, which are found mainly in postmenopausal women. The diagnosis of LCTs in postmenopausal women is associated with specific difficulties and is based on the identification of ...
Larisa V. Suturina, Eldar M. Sharifulin, Maharam A. Sharifulin, Ludmila M. Lazareva, Irina N. Danusevich, Kseniia D. Ievleva, Iana G. Nadeliaeva   +6 more
doaj   +1 more source

High levels of follicular fluid testosterone could impair oocyte developmental competency via affecting aryl hydrocarbon receptor pathway in PCOS patients

BMC Molecular and Cell Biology, 2022
Background Although hormonal and metabolic dysfunction have been recognized as a possible cause of polycystic ovarian syndrome (PCOS), the associations between hyperandrogenism and aryl hydrocarbon receptor (Ahr) signaling pathway remains controversial ...
Fatemeh Eini, Maryam Azizi kutenaei, Tahereh Foroutan, Ensieh Salehi   +3 more
doaj   +1 more source