Results 11 to 20 of about 26,729 (98)

Effects of intraoperative hypercapnia on postoperative brain functional network connectivity and cognitive function in adult patients undergoing Clipping Intracranial Aneurysm [PDF]

BMC Neurology
Background Cerebral vasospasm and delayed cerebral ischemia were significant complications in patients undergoing Clipping Intracranial Aneurysm surgery.
Fengmei Jiao, Guiting Li, Wen Bian
doaj   +2 more sources

Long-term DNA methylation changes induced by age and elevated CO2 in skeletal muscle [PDF]

Skeletal Muscle
Background Skeletal muscle dysfunction and elevated CO2 in the blood, or hypercapnia, are both associated with higher mortality in acute and chronic pulmonary diseases.
Joseph Balnis, Andy Madrid, Emily L. Jackson, Lisa A. Drake, Catherine E. Vincent, Harold A. Singer, Reid S. Alisch, Ariel Jaitovich   +7 more
doaj   +2 more sources

Cerebrovascular reactivity to hypercapnia during sevoflurane or desflurane anesthesia in rats [PDF]

Korean Journal of Anesthesiology, 2019
Background Hypercapnia causes dilation of cerebral vessels and increases cerebral blood flow, resulting in increased intracranial pressure. Sevoflurane is reported to preserve cerebrovascular carbon dioxide reactivity.
Koji Sakata, Kazuhiro Kito, Naokazu Fukuoka, Kiyoshi Nagase, Kumiko Tanabe, Hiroki Iida   +5 more
doaj   +1 more source

Oxygen-induced hypercapnia: physiological mechanisms and clinical implications

Monaldi Archives for Chest Disease, 2022
Oxygen is probably the most commonly prescribed drug in the emergency setting and is a life-saving modality as well. However, like any other drug, oxygen therapy may also lead to various adverse effects.
Malay Sarkar, Irappa Madabhavi, Nagaveni Kadakol   +2 more
doaj   +1 more source

Nocturnal hypercapnia with daytime normocapnia in patients with advanced pulmonary arterial hypertension awaiting lung transplantation.

PLoS ONE, 2020
BACKGROUND:Pulmonary arterial hypertension (PAH) is frequently complicated by sleep disordered breathing (SDB), and previous studies have largely focused on hypoxemic SDB.
Yoshinari Nakatsuka, Toyofumi Chen-Yoshikawa, Hideyuki Kinoshita, Akihiro Aoyama, Hiroyasu Kubo, Kimihiko Murase, Satoshi Hamada, Hirofumi Takeyama, Takuma Minami, Naomi Takahashi, Kiminobu Tanizawa, Tomohiro Handa, Toyohiro Hirai, Hiroshi Date, Kazuo Chin   +14 more
doaj   +1 more source

Hypercapnia increases ACE2 expression and pseudo-SARS-CoV-2 entry in bronchial epithelial cells by augmenting cellular cholesterol

Frontiers in Immunology, 2023
Patients with chronic lung disease, obesity, and other co-morbid conditions are at increased risk of severe illness and death when infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Fei Chen, Aiko Matsuda, G. R. Scott Budinger, G. R. Scott Budinger, Peter H. S. Sporn, Peter H. S. Sporn, S. Marina Casalino-Matsuda   +6 more
doaj   +1 more source

Respiratory Muscle Function Tests and Diaphragm Ultrasound Predict Nocturnal Hypoventilation in Slowly Progressive Myopathies

Frontiers in Neurology, 2021
Introduction: In slowly progressive myopathies, diaphragm weakness early manifests through sleep-related hypoventilation as reflected by nocturnal hypercapnia.
Jens Spiesshoefer, Jens Spiesshoefer, Riccarda Lutter, Hans-Joachim Kabitz, Carolin Henke, Simon Herkenrath, Simon Herkenrath, Winfried Randerath, Winfried Randerath, Peter Young, Michael Dreher, Dennis Görlich, Matthias Boentert, Matthias Boentert   +13 more
doaj   +1 more source

Hypercapnia alters stroma-derived Wnt production to limit β-catenin signaling and proliferation in AT2 cells

JCI Insight, 2023
Persistent symptoms and radiographic abnormalities suggestive of failed lung repair are among the most common symptoms in patients with COVID-19 after hospital discharge. In mechanically ventilated patients with acute respiratory distress syndrome (ARDS)
Laura A. Dada, Lynn C. Welch, Natalia D. Magnani, Ziyou Ren, Hyebin Han, Patricia L. Brazee, Diego Celli, Annette S. Flozak, Anthea Weng, Mariana Maciel Herrerias, Vitalii Kryvenko, István Vadász, Constance E. Runyan, Hiam Abdala-Valencia, Masahiko Shigemura, S. Marina Casalino-Matsuda, Alexander V. Misharin, G.R. Scott Budinger, Cara J. Gottardi, Jacob I. Sznajder   +19 more
doaj   +1 more source

Effects of hypercapnia and NO synthase inhibition in sustained hypoxic pulmonary vasoconstriction

Respiratory Research, 2012
Background Acute respiratory disorders may lead to sustained alveolar hypoxia with hypercapnia resulting in impaired pulmonary gas exchange. Hypoxic pulmonary vasoconstriction (HPV) optimizes gas exchange during local acute (0-30 min), as well as ...
Ketabchi Farzaneh, Ghofrani Hossein A, Schermuly Ralph T, Seeger Werner, Grimminger Friedrich, Egemnazarov Bakytbek, Shid-Moosavi S Mostafa, Dehghani Gholam A, Weissmann Norbert, Sommer Natascha   +9 more
doaj   +1 more source

Hypercapnia attenuates ventilator-induced lung injury through vagus nerve activation [PDF]

Acta Cirúrgica Brasileira, 2019
Purpose: To investigate the role of vagus nerve activation in the protective effects of hypercapnia in ventilator-induced lung injury (VILI) rats.
Wenfang Xia, Guang Li, Zhou Pan, Qingshan Zhou   +3 more
doaj   +1 more source