Hypercapnia attenuates ventilator-induced lung injury through vagus nerve activation [PDF]
Acta Cirúrgica Brasileira, 2019 Purpose: To investigate the role of vagus nerve activation in the protective effects of hypercapnia in ventilator-induced lung injury (VILI) rats.
Wenfang Xia +3 more
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Triggering of erythropoietin production by hypoxia is inhibited by respiratory and metabolic acidosis [PDF]
, 1990 Erythropoietin (EPO) production in response to hypoxic hypoxia is known to be attenuated by simultaneous hypercapnia. This study aimed to investigate whether this inhibitory effect of hypercapnia is 1) a direct effect of carbon dioxide or mediated by ...
Eckardt, K. U. +9 more
core +1 more source
Journal of Neuroinflammation, 2018 Background Cognitive impairment is one of common complications of acute respiratory distress syndrome (ARDS). Increasing evidence suggests that interleukin-1 beta (IL-1β) plays a role in inducing neuronal apoptosis in cognitive dysfunction.
Hong-Guang Ding +11 more
doaj +1 more source
Effects of high-flow nasal cannula in patients with mild to moderate hypercapnia: a prospective observational study [PDF]
Acute and Critical Care, 2021 Background Evidence for using high-flow nasal cannula (HFNC) in hypercapnia is still limited. Most of the clinical studies had been conducted retrospectively, and there had been conflicting reports for the effects of HFNC on hypercapnia correction in ...
Kyung Hun Nam +14 more
doaj +1 more source
Frontiers in Neuroscience, 2019 Long-term hypercapnia is associated with respiratory conditions including obstructive sleep apnea, chronic obstructive pulmonary disease and obesity hypoventilation syndrome.
Ayse Sumeyra Dereli +3 more
doaj +1 more source
Very low tidal volume ventilation with associated hypercapnia--effects on lung injury in a model for acute respiratory distress syndrome. [PDF]
PLoS ONE, 2011 BACKGROUND: Ventilation using low tidal volumes with permission of hypercapnia is recommended to protect the lung in acute respiratory distress syndrome. However, the most lung protective tidal volume in association with hypercapnia is unknown.
Hans Fuchs +4 more
doaj +1 more source
The role of hypercapnia in acute respiratory failure
Intensive Care Medicine Experimental, 2019 The biological effects and physiological consequences of hypercapnia are increasingly understood. The literature on hypercapnia is confusing, and at times contradictory.
Luis Morales-Quinteros +5 more
doaj +1 more source
Effects of Acute Systemic Hypoxia and Hypercapnia on Brain Damage in a Rat Model of Hypoxia-Ischemia. [PDF]
PLoS ONE, 2016 Therapeutic hypercapnia has the potential for neuroprotection after global cerebral ischemia. Here we further investigated the effects of different degrees of acute systemic hypoxia in combination with hypercapnia on brain damage in a rat model of ...
Wanchao Yang +7 more
doaj +1 more source
Frontiers in Physiology, 2022 Background and Objective: Lung-protective mechanical ventilation is known to attenuate ventilator-associated lung injury (VALI), but often at the expense of hypoventilation and hypercapnia.
Nada Ismaiel +8 more
doaj +1 more source
Effect of mild hypercapnia during the recovery period on the emergence time from total intravenous anesthesia: a randomized controlled trial [PDF]
Korean Journal of AnesthesiologyBackground Intraoperative hypercapnia reduces the time to emergence from volatile anesthetics, but few clinical studies have explored the effect of hypercapnia on the emergence time from intravenous (IV) anesthesia. We investigated the effect of inducing
Lan Liu +10 more
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