Results 21 to 30 of about 38,036 (248)

Hypercapnia attenuates ventilator-induced lung injury through vagus nerve activation [PDF]

open access: yesActa Cirúrgica Brasileira, 2019
Purpose: To investigate the role of vagus nerve activation in the protective effects of hypercapnia in ventilator-induced lung injury (VILI) rats.
Wenfang Xia   +3 more
doaj   +1 more source

Triggering of erythropoietin production by hypoxia is inhibited by respiratory and metabolic acidosis [PDF]

open access: yes, 1990
Erythropoietin (EPO) production in response to hypoxic hypoxia is known to be attenuated by simultaneous hypercapnia. This study aimed to investigate whether this inhibitory effect of hypercapnia is 1) a direct effect of carbon dioxide or mediated by ...
Eckardt, K. U.   +5 more
core   +1 more source

The change in cerebrovascular reactivity between 3T and 7T measured using graded hypercapnia [PDF]

open access: yes, 2010
Mapping cerebrovascular reactivity (CVR) to hypercapnia is important both clinically and for improved understanding of the haemodynamic properties of the BOLD effect.
Francis, Susan   +9 more
core   +1 more source

Hypercapnia induces IL-1β overproduction via activation of NLRP3 inflammasome: implication in cognitive impairment in hypoxemic adult rats

open access: yesJournal of Neuroinflammation, 2018
Background Cognitive impairment is one of common complications of acute respiratory distress syndrome (ARDS). Increasing evidence suggests that interleukin-1 beta (IL-1β) plays a role in inducing neuronal apoptosis in cognitive dysfunction.
Hong-Guang Ding   +11 more
doaj   +1 more source

Effects of high-flow nasal cannula in patients with mild to moderate hypercapnia: a prospective observational study [PDF]

open access: yesAcute and Critical Care, 2021
Background Evidence for using high-flow nasal cannula (HFNC) in hypercapnia is still limited. Most of the clinical studies had been conducted retrospectively, and there had been conflicting reports for the effects of HFNC on hypercapnia correction in ...
Kyung Hun Nam   +14 more
doaj   +1 more source

Hypercapnia as a preventative therapeutic strategy: Unveiling the neuroprotective potential and mechanisms

open access: yesBrain Disorders
Hypercapnia, an increase in carbon dioxide (CO2) in the bloodstream, has been historically considered purely a pathological condition. However, based on several publications evaluating the adverse outcome of certain conditions with an additional ...
K. Fazeli, S.B. Jameie, M. Farhadi
doaj   +1 more source

Adaptation of Respiratory-Related Brain Regions to Long-Term Hypercapnia: Focus on Neuropeptides in the RTN

open access: yesFrontiers in Neuroscience, 2019
Long-term hypercapnia is associated with respiratory conditions including obstructive sleep apnea, chronic obstructive pulmonary disease and obesity hypoventilation syndrome.
Ayse Sumeyra Dereli   +3 more
doaj   +1 more source

Very low tidal volume ventilation with associated hypercapnia--effects on lung injury in a model for acute respiratory distress syndrome. [PDF]

open access: yesPLoS ONE, 2011
BACKGROUND: Ventilation using low tidal volumes with permission of hypercapnia is recommended to protect the lung in acute respiratory distress syndrome. However, the most lung protective tidal volume in association with hypercapnia is unknown.
Hans Fuchs   +4 more
doaj   +1 more source

Effect of mild hypercapnia during the recovery period on the emergence time from total intravenous anesthesia: a randomized controlled trial [PDF]

open access: yesKorean Journal of Anesthesiology
Background Intraoperative hypercapnia reduces the time to emergence from volatile anesthetics, but few clinical studies have explored the effect of hypercapnia on the emergence time from intravenous (IV) anesthesia. We investigated the effect of inducing
Lan Liu   +10 more
doaj   +1 more source

Effects of Acute Systemic Hypoxia and Hypercapnia on Brain Damage in a Rat Model of Hypoxia-Ischemia. [PDF]

open access: yesPLoS ONE, 2016
Therapeutic hypercapnia has the potential for neuroprotection after global cerebral ischemia. Here we further investigated the effects of different degrees of acute systemic hypoxia in combination with hypercapnia on brain damage in a rat model of ...
Wanchao Yang   +7 more
doaj   +1 more source

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