Results 21 to 30 of about 56,541 (302)

Sub-cortical and brainstem sites associated with chemo-stimulated increases in ventilation in humans [PDF]

, 2010
We investigated the neural basis for spontaneous chemo-stimulated increases in ventilation in awake, healthy humans. Blood oxygen level dependent (BOLD) functional MRI was performed in nine healthy subjects using T2weighted echo planar imaging.
Ackland, Akopyan, Banzett, Bertrand, Bianchi, Brannan, Cavanna, Cechetto, Chamberlin, Chamberlin, Chen, Colebatch, Corfield, Corfield, Critchley, Dick, Douglas, Douglas, Douglas R. Corfield, Duvernoy, Duvernoy, Evans, Evans, Fink, Fink, Friston, Friston, Gandevia, Gaytan, Gray, Haines, Harper, Herbert, Heywood, Hugo D. Critchley, Isaev, Kevin Murphy, Kjaer, Koos, Kubin, Kumar, Lavezzi, Leanne C. McKay, Macey, McKay, McKay, McKay, Middleton, Mink, Nathan, Pattinson, Peiffer, Plum, Plum, Ramsay, Richard S.J. Frackowiak, Schmahmann, Schwarzacher, Severinghaus, Shea, Skatrud, Smith, Smith, Talairach, Wenninger, Worsley, Xu, Yokota   +67 more
core   +2 more sources

Respiratory Muscle Function Tests and Diaphragm Ultrasound Predict Nocturnal Hypoventilation in Slowly Progressive Myopathies

Frontiers in Neurology, 2021
Introduction: In slowly progressive myopathies, diaphragm weakness early manifests through sleep-related hypoventilation as reflected by nocturnal hypercapnia.
Jens Spiesshoefer, Jens Spiesshoefer, Riccarda Lutter, Hans-Joachim Kabitz, Carolin Henke, Simon Herkenrath, Simon Herkenrath, Winfried Randerath, Winfried Randerath, Peter Young, Michael Dreher, Dennis Görlich, Matthias Boentert, Matthias Boentert   +13 more
doaj   +1 more source

Hypercapnia alters stroma-derived Wnt production to limit β-catenin signaling and proliferation in AT2 cells

JCI Insight, 2023
Persistent symptoms and radiographic abnormalities suggestive of failed lung repair are among the most common symptoms in patients with COVID-19 after hospital discharge. In mechanically ventilated patients with acute respiratory distress syndrome (ARDS)
Laura A. Dada, Lynn C. Welch, Natalia D. Magnani, Ziyou Ren, Hyebin Han, Patricia L. Brazee, Diego Celli, Annette S. Flozak, Anthea Weng, Mariana Maciel Herrerias, Vitalii Kryvenko, István Vadász, Constance E. Runyan, Hiam Abdala-Valencia, Masahiko Shigemura, S. Marina Casalino-Matsuda, Alexander V. Misharin, G.R. Scott Budinger, Cara J. Gottardi, Jacob I. Sznajder   +19 more
doaj   +1 more source

Ventilatory Phenotypes among Four Strains of Adult Rats. [PDF]

, 2002
Our purpose in this study was to identify different ventilatory phenotypes among four different strains of rats. We examined 114 rats from three in-house, inbred strains and one outbred strain: Brown Norway (BN;n = 26), Dahl salt-sensitive (n = 24), Fawn-
Dwinell, Melinda R., Forster, Hubert, Hodges, Matthew, Hogan, Genevieve E., Papanek, Paula   +4 more
core   +2 more sources

Effects of hypercapnia and NO synthase inhibition in sustained hypoxic pulmonary vasoconstriction

Respiratory Research, 2012
Background Acute respiratory disorders may lead to sustained alveolar hypoxia with hypercapnia resulting in impaired pulmonary gas exchange. Hypoxic pulmonary vasoconstriction (HPV) optimizes gas exchange during local acute (0-30 min), as well as ...
Ketabchi Farzaneh, Ghofrani Hossein A, Schermuly Ralph T, Seeger Werner, Grimminger Friedrich, Egemnazarov Bakytbek, Shid-Moosavi S Mostafa, Dehghani Gholam A, Weissmann Norbert, Sommer Natascha   +9 more
doaj   +1 more source

Hypercapnia attenuates ventilator-induced lung injury through vagus nerve activation [PDF]

Acta Cirúrgica Brasileira, 2019
Purpose: To investigate the role of vagus nerve activation in the protective effects of hypercapnia in ventilator-induced lung injury (VILI) rats.
Wenfang Xia, Guang Li, Zhou Pan, Qingshan Zhou   +3 more
doaj   +1 more source

Effects of Permissive Hypercapnia on Laparoscopic Surgery for Rectal Carcinoma

Gastroenterology Research and Practice, 2019
Background. Permissive hypercapnia has been recommended during the treatment of chronic diseases; however, there are insufficient clinical data to investigate the feasibility of permissive hypercapnia in relatively long-term surgeries such as ...
Lei Wang, Lina Yang, Jing Yang, Shiqiang Shan   +3 more
doaj   +1 more source

Age Related Changes in Cerebrovascular Reactivity and Its Relationship to Global Brain Structure [PDF]

, 2015
ACKNOWLEDGMENTS This study was funded by Alzheimer’s Research UK (ARUK) and the Aberdeen Biomedical Imaging Centre, University of Aberdeen. GDW, ADM and CS are part of the SINASPE collaboration (Scottish Imaging Network - A Platform for Scientific ...
Ahearn, Trevor S., Cameron, George G., Murray, Alison D., Schwarzbauer, Christian, Waiter, Gordon D.   +4 more
core   +1 more source

Graded Hypercapnia-Calibrated BOLD: Beyond the Iso-metabolic Hypercapnic Assumption

Frontiers in Neuroscience, 2017
Calibrated BOLD is a promising technique that overcomes the sensitivity of conventional fMRI to the cerebrovascular state; measuring either the basal level, or the task-induced response of cerebral metabolic rate of oxygen consumption (CMRO2).
Ian D. Driver, Richard G. Wise, Kevin Murphy, Kevin Murphy   +3 more
doaj   +1 more source

Therapeutic hypercapnia for prevention of secondary ischemia after severe subarachnoid hemorrhage: physiological responses to continuous hypercapnia

Scientific Reports, 2021
Temporary hypercapnia has been shown to increase cerebral blood flow (CBF) and might be used as a therapeutical tool in patients with severe subarachnoid hemorrhage (SAH).
Christian Stetter, Franziska Weidner, Nadine Lilla, Judith Weiland, Ekkehard Kunze, Ralf-Ingo Ernestus, Ralf Michael Muellenbach, Thomas Westermaier   +7 more
doaj   +1 more source