Results 11 to 20 of about 27,845 (231)

Respiratory Muscle Function Tests and Diaphragm Ultrasound Predict Nocturnal Hypoventilation in Slowly Progressive Myopathies

open access: yesFrontiers in Neurology, 2021
Introduction: In slowly progressive myopathies, diaphragm weakness early manifests through sleep-related hypoventilation as reflected by nocturnal hypercapnia.
Jens Spiesshoefer   +13 more
doaj   +1 more source

Hypercapnia alters stroma-derived Wnt production to limit β-catenin signaling and proliferation in AT2 cells

open access: yesJCI Insight, 2023
Persistent symptoms and radiographic abnormalities suggestive of failed lung repair are among the most common symptoms in patients with COVID-19 after hospital discharge. In mechanically ventilated patients with acute respiratory distress syndrome (ARDS)
Laura A. Dada   +19 more
doaj   +1 more source

Effects of hypercapnia and NO synthase inhibition in sustained hypoxic pulmonary vasoconstriction

open access: yesRespiratory Research, 2012
Background Acute respiratory disorders may lead to sustained alveolar hypoxia with hypercapnia resulting in impaired pulmonary gas exchange. Hypoxic pulmonary vasoconstriction (HPV) optimizes gas exchange during local acute (0-30 min), as well as ...
Ketabchi Farzaneh   +9 more
doaj   +1 more source

Effects of Permissive Hypercapnia on Laparoscopic Surgery for Rectal Carcinoma

open access: yesGastroenterology Research and Practice, 2019
Background. Permissive hypercapnia has been recommended during the treatment of chronic diseases; however, there are insufficient clinical data to investigate the feasibility of permissive hypercapnia in relatively long-term surgeries such as ...
Lei Wang   +3 more
doaj   +1 more source

Hypercapnia attenuates ventilator-induced lung injury through vagus nerve activation [PDF]

open access: yesActa Cirúrgica Brasileira, 2019
Purpose: To investigate the role of vagus nerve activation in the protective effects of hypercapnia in ventilator-induced lung injury (VILI) rats.
Wenfang Xia   +3 more
doaj   +1 more source

Effects of hypercapnia on the lung [PDF]

open access: yesThe Journal of Physiology, 2017
AbstractGases are sensed by lung cells and can activate specific intracellular signalling pathways, and thus have physiological and pathophysiological effects. Carbon dioxide (CO2), a primary product of oxidative metabolism, can be sensed by eukaryotic cells eliciting specific responses via recently identified signalling pathways.
Masahiko Shigemura   +2 more
openaire   +2 more sources

Graded Hypercapnia-Calibrated BOLD: Beyond the Iso-metabolic Hypercapnic Assumption

open access: yesFrontiers in Neuroscience, 2017
Calibrated BOLD is a promising technique that overcomes the sensitivity of conventional fMRI to the cerebrovascular state; measuring either the basal level, or the task-induced response of cerebral metabolic rate of oxygen consumption (CMRO2).
Ian D. Driver   +3 more
doaj   +1 more source

Therapeutic hypercapnia for prevention of secondary ischemia after severe subarachnoid hemorrhage: physiological responses to continuous hypercapnia

open access: yesScientific Reports, 2021
Temporary hypercapnia has been shown to increase cerebral blood flow (CBF) and might be used as a therapeutical tool in patients with severe subarachnoid hemorrhage (SAH).
Christian Stetter   +7 more
doaj   +1 more source

Hypercapnia induces IL-1β overproduction via activation of NLRP3 inflammasome: implication in cognitive impairment in hypoxemic adult rats

open access: yesJournal of Neuroinflammation, 2018
Background Cognitive impairment is one of common complications of acute respiratory distress syndrome (ARDS). Increasing evidence suggests that interleukin-1 beta (IL-1β) plays a role in inducing neuronal apoptosis in cognitive dysfunction.
Hong-Guang Ding   +11 more
doaj   +1 more source

Very low tidal volume ventilation with associated hypercapnia--effects on lung injury in a model for acute respiratory distress syndrome. [PDF]

open access: yesPLoS ONE, 2011
BACKGROUND: Ventilation using low tidal volumes with permission of hypercapnia is recommended to protect the lung in acute respiratory distress syndrome. However, the most lung protective tidal volume in association with hypercapnia is unknown.
Hans Fuchs   +4 more
doaj   +1 more source

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