Results 51 to 60 of about 199,665 (351)

Label‐Free Leukocyte Biophysical Profiling Using Impedance‐Deformability Cytometry for Rapid Cardiovascular Risk Stratification

Advanced Science, EarlyView.
This study presents an impedance‐based single‐cell profiling platform that quantifies the electrical and mechanical properties of neutrophils across in vitro, in vivo, and clinical samples. The approach reveals distinct biophysical alterations associated with type 2 diabetes (T2DM) and cardiovascular complications, suggesting its potential utility for ...
Linwei He, Hui Min Tay, Feng Chen, Hong Sheng Cheng, Liang De Wang, Qiqi Nam, Arunachalam Thannirmalai, Lingyan Gong, Aram J. Chung, Nguan Soon Tan, King Ho Holden Li, Rinkoo Dalan, Siu Ling Wong, Han Wei Hou   +13 more
wiley   +1 more source

Relationship Of Waist Circumference And Hypercholesterolemia Incidence In Patient With Hypertension in Tegal Gundil Public Health Center at Bogor City

Jurnal Kesehatan Komunitas (Journal of Community Health), 2019
Hypertension and hypercholesterolemia are the causes of coronary heart disease (CHD) so that the presence of hypercholesterolemia in patients with hypertension will increase the risk of CHD.
Siti Hana, Ratu Ayu Dewi Sartika
doaj   +1 more source

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

Advanced Science, EarlyView.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo, Lanjie Lei, Ying Jin, Lan Su, Shumao Cui, Liyun Shi   +5 more
wiley   +1 more source

Plant sterols for adults with hypercholesterolemia treated with or without medication (statins)

Revista Española de Nutrición Humana y Dietética, 2015
Hypercholesterolemia is the most common coronary risk factor among the Spanish population; 37.4% of the Spanish adult population have cholesterol levels between 190 and 240 mg/dl.
Raquel Bernácer, Diana Roig, Blanca Lozano   +2 more
doaj   +1 more source

Cholesterol Promotes Lung Adenocarcinoma Brain Metastasis by Stabilizing EGFR Protein to Drive EMT, Metabolic Reprogramming, and Premetastatic Niche Formation

Advanced Science, EarlyView.
Cholesterol is revealed as a multitasking fuel for lung adenocarcinoma brain metastasis: it locks EGFR at the membrane to sustain AKT/NF‐κB–driven glycolysis and EMT, loosens the blood–brain barrier by promoting Claudin‐5 loss, and rewires microglia through IL‐4R lipid‐raft–JAK1/STAT6 signaling.
Ying Chen, Xiaoteng Cui, Xinyi Shi, Xu Yang, Yujing Cao, Haolin LI, Qi Zhan, Qixue Wang, Ang Li, Qihong Cheng, Yunfei Wang, Junhu Zhou, MingJie Wang, Chunsheng Kang, Xiaomin Liu   +14 more
wiley   +1 more source

Threat of Hypercholesterolemia in Urban Adults and Its Associates: Evidence from a Community-Based Study

Makara Journal of Health Research
Background: Hypercholesterolemia is an abnormality of lipids. It is a crucial modifiable risk factor for cardiovascular diseases. There is a paucity of community-based studies on hypercholesterolemia in the adult population in India.
Ambika Rani Yadav, Priya Keshari
doaj   +1 more source

COMPARATIVE STUDY OF HYPOCHOLESTEROLEMIC EFFECT ON TAURINE ANDSIMVASTATIN IN MALE RATS [PDF]

Basrah Journal of Veterinary Research, 2016
This study was conducted to investigate the effect of Taurine as hypocholesterolemic agentand compare with the results of simvastatin drug on male rats. The experiment consisted of 36adult male rats (Rattus norvegicus) weighting range 170 -200 gm divided
Hanadi Al_hilfi, Ahlam Al-Rekabi, Wasfi Al- Masoudi, kamal alsaad, Abdulkadhim Aneed, Karima Al-Salihi, Ali Ajeel, Kasim Hussein Ali, Iman AlShati, Najlaa Ibrahim, Nadhim Jakhsi, Gahin Taib, Mahdi Abdullah, Rizgar Nabi, Nameer A.Kareem Al zubaidi, Mortadha Salh Hatim   +15 more
doaj   +1 more source

Impact of metabolic comorbidity on the association between body mass index and heatlh-related quality of life: a Scotland-wide cross-sectional study of 5,608 participants [PDF]

, 2012
<p/>Background: The prevalence of obesity is rising in Scotland and globally. Overall, obesity is associated with increased morbidity, mortality and reduced health-related quality of life.
A Peeters, Daniel F Mackay, DS Morrison, E Lopez-Garcia, EA Sims, Elisabeth Fenwick, ES Ford, FB Hu, G Iacobellis, GA Bray, GA Colditz, H Jia, HA Doll, HL Wee, I Castres, J Brazier, Jill P Pell, JM Rippe, K Trakas, KM Flegal, KR Fontaine, KR Fontaine, LL Yan, MA Friedman, MA Friedman, MJ Garcia-Mendizabal, MK Hassan, N Stefan, N Vasiljevic, RF Kushner, RL Kolotkin, RP Wildman, RP Wildman, S Sarlio-Lahteenkorva, S Velho, SJ Olshansky, TG Bentley, TH Sach, WM Hopman, World Health Organization, Zia Ul-Haq   +40 more
core   +3 more sources

Genomics knowledge and attitudes among European public health professionals. Results of a cross-sectional survey [PDF]

, 2020
Background The international public health (PH) community is debating the opportunity to incorporate genomic technologies into PH practice. A survey was conducted to assess attitudes of the European Public Health Association (EUPHA) members towards their
Baccolini, V., Barnhoorn, F., D'Andrea, E., de Vito, C., Marco, M. D., Marzuillo, C., Paget, D. Z., Pitini, E., Rosso, A., Unim, B., Villari, P.   +10 more
core   +2 more sources

Growth Standards for Children With Smith–Magenis Syndrome (SMS)

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Smith–Magenis syndrome (SMS, OMIM 182290) is a complex syndromic diagnosis marked by neurobehavioral differences and distinct facial dysmorphisms, caused by haploinsufficiency of the retinoic acid‐1 (RAI1) gene either by a pathogenic sequence variant or deletion at chromosome 17p11.2 involving a portion or all of this gene.
Julie Hoover‐Fong, John McGready, Leah Fleming, Kerry Schulze, Folami Duncan, Alexis Leonard, Marie Christine de Blois Boucard, Danilo Moretti‐Ferreira, Andrea L. Gropman, Wendy J. Introne, Ann C. M. Smith   +10 more
wiley   +1 more source