Results 71 to 80 of about 182,065 (262)

Impact of metabolic comorbidity on the association between body mass index and heatlh-related quality of life: a Scotland-wide cross-sectional study of 5,608 participants [PDF]

, 2012
<p/>Background: The prevalence of obesity is rising in Scotland and globally. Overall, obesity is associated with increased morbidity, mortality and reduced health-related quality of life.
A Peeters, Daniel F Mackay, DS Morrison, E Lopez-Garcia, EA Sims, Elisabeth Fenwick, ES Ford, FB Hu, G Iacobellis, GA Bray, GA Colditz, H Jia, HA Doll, HL Wee, I Castres, J Brazier, Jill P Pell, JM Rippe, K Trakas, KM Flegal, KR Fontaine, KR Fontaine, LL Yan, MA Friedman, MA Friedman, MJ Garcia-Mendizabal, MK Hassan, N Stefan, N Vasiljevic, RF Kushner, RL Kolotkin, RP Wildman, RP Wildman, S Sarlio-Lahteenkorva, S Velho, SJ Olshansky, TG Bentley, TH Sach, WM Hopman, World Health Organization, Zia Ul-Haq   +40 more
core   +3 more sources

Hypoxia-induced NOS1 as a therapeutic target in hypercholesterolemia-related colorectal cancer

Cancer & Metabolism
Background It is well established that hypercholesterolemia increases the risk of atherosclerosis, especially because it reduces the availability of nitric oxide (NO). However, the relationship between hypercholesterolemia and NO in regulating colorectal
Weiqing Qiu, Li Zhao, Hua Liu, Ping Xu, Changlin Qian   +4 more
doaj   +1 more source

Genetically confirmed familial hypercholesterolemia in outpatients with hypercholesterolemia.

Journal of geriatric cardiology : JGC, 2018
Familial hypercholesterolemia (FH) is an autosomal dominant disorder of lipoprotein metabolism which can lead to premature coronary heart disease (pCHD). There are about 3.8 million potential FH patients in China, whereas the clinical and genetic data of FH are limited.Dutch Lipid Clinic Network (DLCN) criteria was used to diagnose FH in outpatients ...
Wei Liu, Xu Wang, Long Jiang, Wenhui Wen, Yujie Zhou, Xi-Fu Wang, Lu-Ya Wang, Yue Wu, Li-Yuan Sun   +8 more
openaire   +2 more sources

Causal relationship between mental disorders and hypercholesterolemia： a Mendelian randomization analysis

Sichuan jingshen weisheng
BackgroundMetabolic syndrome （MetS） is highly prevalent in patients with mental disorders， including elevated diastolic or systolic blood pressure， elevated fasting glucose， hypercholesterolemia， abdominal obesity and so on.
Zou Qian, Tang Ni, Liu Huanhui, Zhang Hanjing, Ma Xiaojie   +4 more
doaj   +1 more source

Markers of early target-organ brain damage in essential arterial hypertension: the search continues. Possibilities of diffusion tensor magnetic resonance imaging [PDF]

Системные гипертензии, 2017
Rosuvastatin is one of the most frequently prescribed drugs for primary and secondary prevention of myocardial infarction and stroke. The present article deals with the main studies confirming the effectiveness of rosuvastatin in patients with different ...
G S Anikin, I K Storozhuk, Ya Yu Filyazova   +2 more
doaj  

Determination of Pericardial Adipose Tissue Increases the Prognostic Accuracy of Coronary Artery Calcification for Future Cardiovascular Events [PDF]

, 2012
Objectives: Pericardial adipose tissue (PAT) is associated with coronary artery plaque accumulation and the incidence of coronary heart disease. We evaluated the possible incremental prognostic value of PAT for future cardiovascular events.
Agatston AS, Ahn SG, Alexander Becker, Alexander Wolfgang Leber, Anand DV, Becker A, Becker A, Budoff MJ, Cheng VY, Christoph Becker, Christopher Uebleis, Dandona P, Detrano R, Ding J, Feldman DN, Franz von Ziegler, Gerhard Steinbeck, Greenland P, Greif M, Grundy SM, Janine Rümmler, Jeong JW, Keelan PC, Marcus Hacker, Martin Greif, Melvin D’Anastasi, Rabkin SW, Raggi P, Rumberger JA, Sacks HS, Schenker MP, Shareghi S, Tobias Saam, Uebleis C, Vivian Arias-Herrera, Wayhs R   +35 more
core   +1 more source

Mechanisms of oxidative stress in human aortic aneurysms — association with clinical risk factors for atherosclerosis and disease severity [PDF]

, 2013
Aortic abdominal aneurysms (AAA) are important causes of cardiovascular morbidity and mortality. Oxidative stress may link multiple mechanisms of AAA including vascular inflammation and increased metalloproteinase activity.
Bujak-Gizycka, Beata, Chwała, Maciej, Filip, Grzegorz, Grudzien, Grzegorz, Guzik, Bartłomiej, Guzik, Tomasz J., Kapelak, Boguslaw, Korbut, Ryszard, Ludew, Dominik, Mrowiecki, Tomasz, Mrowiecki, Wojciech, Sadowski, Jerzy, Sagan, Agnieszka, Żmudka, Krzysztof   +13 more
core   +2 more sources

Effects of oxidized low density lipoprotein, lipid mediators and statins on vascular cell interactions [PDF]

, 1999
The integrin heterodimer CD11b/CD18 (alpha M beta 2, Mac-1, CR3) expressed on monocytes or polymorphonuclear leukocytes (PMN) is a receptor for iC3b, fibrinogen, heparin, and for intercellular adhesion molecule (ICAM)-1 on endothelium, crucially ...
Amatruda TT, Bednar MM, Bellosta S, Buttrum SM, Buyon JP, Calara F, Calderon TM, Diacovo TG, Giroux LM, Jukema JW, Kim JA, Kimura M, Laufs U, Laws KH, Lehr H-A, Marcus AJ, Notabartolo A, Olstrowsky L, Pons F, Ruf A, Smalley DM, Stragliotto E, Sugiyama S, Weber C, Weber C, Weber C, Yeagle PL, Yeo EL, Yue TL   +28 more
core   +1 more source

ApoE gene therapy: an overview and update [PDF]

, 2005
Atherosclerosis remains the leading cause of death in industrialized societies. Apolipoprotein E (ApoE) is an attractive candidate to treat hypercholesterolemia and coronary heart disease, as it is a circulating protein with pleiotropic ...
Owen, J.S.
core  

Lipoprotein(a) in children and adolescents with genetically confirmed familial hypercholesterolemia followed up at a specialized lipid clinic

Atherosclerosis Plus
Background and aim: Many children with an FH mutation also exhibit elevated lipoprotein(a) levels, which is an independent risk factor for atherosclerotic cardiovascular disease.
Anja K. Johansen, Martin P. Bogsrud, Magne Thoresen, Jacob J. Christensen, Ingunn Narverud, Gisle Langslet, Tone Svilaas, Kjetil Retterstøl, Kirsten B. Holven   +8 more
doaj