Results 11 to 20 of about 31,250 (276)

Protective vascular and cardiac effects of inducible nitric oxide synthase in mice with hyperhomocysteinemia. [PDF]

PLoS ONE, 2014
Diet-induced hyperhomocysteinemia produces endothelial and cardiac dysfunction and promotes thrombosis through a mechanism proposed to involve oxidative stress.
Sanjana Dayal, Ilya O Blokhin, Rochelle A Erger, Melissa Jensen, Erland Arning, Jeff W Stevens, Teodoro Bottiglieri, Frank M Faraci, Steven R Lentz   +8 more
doaj   +1 more source

Deficiency of superoxide dismutase promotes cerebral vascular hypertrophy and vascular dysfunction in hyperhomocysteinemia. [PDF]

PLoS ONE, 2017
There is an emerging consensus that hyperhomocysteinemia is an independent risk factor for cerebral vascular disease and that homocysteine-lowering therapy protects from ischemic stroke.
Sanjana Dayal, Gary L Baumbach, Erland Arning, Teodoro Bottiglieri, Frank M Faraci, Steven R Lentz   +5 more
doaj   +1 more source

Case report: Young-onset large vessel ischemic stroke due to hyperhomocysteinemia associated with the C677T polymorphism on 5,10-methylenetetrahydrofolate reductase and multi-vitamin deficiency

Frontiers in Neurology, 2023
Hyperhomocysteinemia is an important risk factor for cerebral infarction. Herein, we report on a 30-year-old man previously diagnosed with epilepsy who presented with right hemiplegia and total aphasia. Magnetic resonance imaging showed a fronto-temporal
Jiro Fukae, Hiroto Eguchi, Yoichi Wada, Atsuhito Fuse, Rika Chishima, Mitsuyoshi Nakatani, Asuka Nakajima, Asuka Nakajima, Nobutaka Hattori, Yasushi Shimo, Yasushi Shimo   +10 more
doaj   +1 more source

Evaluation of platelet distribution width in hypertension with hyperhomocysteinemia

Clinical and Experimental Hypertension, 2020
An increased platelet distribution width (PDW) value has been found in various cardiovascular diseases. The objective of this study was to evaluate the association between the PDW and hypertension with hyperhomocysteinemia in an elderly cohort.
Gang Li, Yanyan Zhang, Zhongwei Zhu, Juan Du   +3 more
doaj   +1 more source

Genetic and Metabolic Markers for Cognition: The Interplay of Hyperhomocysteinemia and ApoE Genotype [PDF]

Alzheimers Dement
Abstract Background The presence of ApoE4 allele is known to be the most important genetic risk factor for Late Onset Alzheimer's Disease (LOAD). Hyperhomocysteinemia (HHcy), a cardiovascular risk factor, is also being extensively studied for its role in increasing the risk of cognitive decline in the elderly.
Natarajan S, S M, Issac T.
europepmc   +2 more sources

Hyperhomocysteinemia induced by excessive methionine intake promotes rupture of cerebral aneurysms in ovariectomized rats. [PDF]

, 2016
BackgroundHyperhomocysteinemia (HHcy) is associated with inflammation and a rise in the expression of matrix metalloproteinase-9 (MMP-9) in the vascular wall.
Hashimoto, Tomoki, Kanematsu, Yasuhisa, Kitazato, Keiko T, Korai, Masaaki, Matsushita, Nobuhisa, Miyamoto, Takeshi, Nagahiro, Shinji, Satomi, Junichiro, Shimada, Kenji, Tada, Yoshiteru   +9 more
core   +2 more sources

Homocysteine in cerebrovascular disease: An independent risk factor for subcortical vascular encephalopathy [PDF]

, 2001
Hyperhomocysteinemia is a risk factor for obstructive large-vessel disease. Here, we studied plasma concentrations of homocysteine and vitamins in patients suffering from subcortical vascular encephalopathy (SVE), a cerebral small-vessel disease leading ...
Aufenanger, Johannes, Bertsch, Thomas, Casarin, Wendy, Fassbender, Klaus, Höly, Sabine, Kuehl, Sandra, Mielke, Orell, Muehlhauser, Frank, Ragoschke, Andreas, Walter, Silke, Zimmer, Wilma   +10 more
core   +1 more source

ADMA and hyperhomocysteinemia [PDF]

Vascular Medicine, 2005
Hyperhomocysteinemia is a risk factor for cardiovascular disease and stroke. Like many other cardiovascular risk factors, hyperhomocysteinemia produces endothelial dysfunction due to impaired bioavailability of endothelium-derived nitric oxide (NO).
Sanjana, Dayal, Steven R, Lentz
openaire   +2 more sources

Transcobalamin C776G genotype modifies the association between vitamin B12 and homocysteine in older Hispanics. [PDF]

, 2010
Background/objectivesA common polymorphism, C776G, in the plasma B12 transport protein transcobalamin (TC), encodes for either proline or arginine at codon 259.
Allen, LH, Garrod, MG, Green, R, Haan, MN, Miller, JW   +4 more
core   +2 more sources

Anemia, hematinic deficiencies, and hyperhomocysteinemia in serum gastric parietal cell antibody-positive burning mouth syndrome patients without serum thyroid autoantibodies

Journal of Dental Sciences, 2021
Background/purpose: Our previous study found that 70 of 884 burning mouth syndrome (BMS) patients have serum gastric parietal cell antibody (GPCA) positivity but without thyroglobulin antibody (TGA) and thyroid microsomal antibody (TMA) (so-called GPCA ...
Ying-Tai Jin, Yu-Hsueh Wu, Yang-Che Wu, Julia Yu-Fong Chang, Chun-Pin Chiang, Andy Sun   +5 more
doaj   +1 more source