Results 21 to 30 of about 26,695 (224)

Evaluation of platelet distribution width in hypertension with hyperhomocysteinemia

Clinical and Experimental Hypertension, 2020
An increased platelet distribution width (PDW) value has been found in various cardiovascular diseases. The objective of this study was to evaluate the association between the PDW and hypertension with hyperhomocysteinemia in an elderly cohort.
Gang Li, Yanyan Zhang, Zhongwei Zhu, Juan Du   +3 more
doaj   +1 more source

Anemia, hematinic deficiencies, and hyperhomocysteinemia in serum gastric parietal cell antibody-positive burning mouth syndrome patients without serum thyroid autoantibodies

Journal of Dental Sciences, 2021
Background/purpose: Our previous study found that 70 of 884 burning mouth syndrome (BMS) patients have serum gastric parietal cell antibody (GPCA) positivity but without thyroglobulin antibody (TGA) and thyroid microsomal antibody (TMA) (so-called GPCA ...
Ying-Tai Jin, Yu-Hsueh Wu, Yang-Che Wu, Julia Yu-Fong Chang, Chun-Pin Chiang, Andy Sun   +5 more
doaj   +1 more source

Hyperhomocysteinemia: Clinical Insights

Journal of Central Nervous System Disease, 2020
Homocysteine (Hcy) is a sulfhydryl-containing amino acid, and intermediate metabolite formed in metabolising methionine (Met) to cysteine (Cys); defective Met metabolism can increase Hcy. The effect of hyperhomocysteinemia (HHcy) on human health, is well
F. Al Mutairi
semanticscholar   +1 more source

Implication of Hyperhomocysteinemia in Blood Retinal Barrier (BRB) Dysfunction

Biomolecules, 2020
Elevated plasma homocysteine (Hcy) level, known as hyperhomocysteinemia (HHcy) has been linked to different systemic and neurological diseases, well-known as a risk factor for systemic atherosclerosis and cardiovascular disease (CVD) and has been ...
A. Tawfik, Yara A Samra, N. Elsherbiny, M. Al-Shabrawey   +3 more
semanticscholar   +1 more source

Homocysteine-lowering gene therapy rescues signaling pathways in brain of mice with intermediate hyperhomocysteinemia

Redox Biology, 2018
Hyperhomocysteinemia due to cystathionine beta synthase (CBS) deficiency is associated with diverse cognitive dysfunction. Considering the role of the serine/threonine kinase DYRK1A, not only in developmental defects with life-long structural and ...
Vanessa Baloula, Marta Fructuoso, Nadim Kassis, Dalale Gueddouri, Jean-Louis Paul, Nathalie Janel   +5 more
doaj   +1 more source

The involvement of hyperhomocysteinemia in the development of characterized depressive disorder in children and adolescents

European Psychiatry, 2023
Introduction Elevated blood levels of homocysteine have been associated with several psychiatric and neurodegenerative disorders such as schizophrenic disorders, Alzheimer’s disease, Parkinson’s disease and depression. The hypothesis is that genetic and
Z. Elmaataoui, H. BELHADGA, H. KISRA
doaj   +1 more source

Hyperhomocysteinemia as a Risk Factor and Potential Nutraceutical Target for Certain Pathologies

Frontiers in Nutrition, 2019
Hyperhomocysteinemia is recognized as a risk factor for several diseases, including cardiovascular and neurological conditions. Homocysteine (HCys) is a key metabolite involved in the biosynthesis and metabolism of methionine (Met), which plays a pivotal
C. Tinelli, Antonella Di Pino, E. Ficulle, S. Marcelli, M. Feligioni   +4 more
semanticscholar   +1 more source

Role of hyperhomocysteinemia and Vitamin B12 deficiency in central and hemi-central retinal vein occlusion: A case–control study

Oman Journal of Ophthalmology, 2022
BACKGROUND: Retinal venous occlusive diseases have been recognized as a major cause of ocular morbidity. Hyperhomocysteinemia could be a potentially modifiable risk factor.
Dhipak Arthur, Deepa John, Jude Joseph Fleming, Grace Rebekah, Mahasampath Gowri, Sheeja Susan John   +5 more
doaj   +1 more source

Hyperhomocysteinemia and Endothelial Dysfunction in Multiple Sclerosis

Brain Science, 2020
Endothelial dysfunction is recognized as one of the leading factors in the pathogenesis of diseases of the central nervous system of various etiologies.
E. Dubchenko, A. Ivanov, N. Spirina, N. Smirnova, M. Melnikov, A. Boyko, E. Gusev, A. Kubatiev   +7 more
semanticscholar   +1 more source

Cystathionine β-synthase and methylenetetrahydrofolate reductase mutations in Mexican individuals with hyperhomocysteinemia

SAGE Open Medicine, 2020
Background: Hyperhomocysteinemia, a thrombotic risk factor, may have several causes. Among the genetic causes of hyperhomocysteinemia, there are polymorphisms in the enzymes methylenetetrahydrofolate reductase (C677T) and cystathionine β-synthase (C699T,
Anahi Guadalupe Figueroa-Torres, Lisneth Osiris Matias-Aguilar, Erika Coria-Ramirez, Edmundo Bonilla-Gonzalez, Humberto Gonzalez-Marquez, Isabel Ibarra-Gonzalez, Jose Rubicel Hernandez-Lopez, Jesus Hernandez-Juarez, Victor Manuel Dominguez-Reyes, Irma Isordia-Salas, Abraham Majluf-Cruz   +10 more
doaj   +1 more source