Introduction Elevated blood levels of homocysteine have been associated with several psychiatric and neurodegenerative disorders such as schizophrenic disorders, Alzheimer’s disease, Parkinson’s disease and depression. The hypothesis is that genetic and
Z. Elmaataoui, H. BELHADGA, H. KISRA
doaj +1 more source
Thrombophilia in hyperhomocysteinemia [PDF]
A 23-year-old otherwise healthy male presented with development of painful blackish discoloration of the right thumb and index finger and of the right big toe and area over the ankle (Figs. 1 and and2),2), as well as painful swelling of both lower limbs, especially on the right side (Fig. 3). Homans′sign was present bilaterally.
Sharma, Vishal +4 more
openaire +2 more sources
Influence of homocysteine on the physical structure and molecular mobility of elastin network in cultured arteries [PDF]
The thermal and dielectric properties of the elastin network were investigated in arteries cultured with physiological and pathological concentrations of homocysteine, an aminoacid responsible of histological impairments in human arteries.
Chareyre, Corinne +6 more
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Hyperhomocysteinemia increases risk of death, especially in type 2 diabetes: 5-year follow-up of the Hoorn Study. [PDF]
A high serum total homocysteine (tHcy) level is an independent risk factor for cardiovascular disease. Because it is not known whether the strength of the association between hyperhomocysteinemia and cardiovascular disease is similar for peripheral ...
Bouter, L.M. +7 more
core +7 more sources
The sheep conceptus modulates proteome profiles in caruncular endometrium during early pregnancy [PDF]
This project was funded by NHS Grampian R&D project number RG05/019Peer ...
Al-Gubory, Kaïs +2 more
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BACKGROUND: Retinal venous occlusive diseases have been recognized as a major cause of ocular morbidity. Hyperhomocysteinemia could be a potentially modifiable risk factor.
Dhipak Arthur +5 more
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Background: Hyperhomocysteinemia, a thrombotic risk factor, may have several causes. Among the genetic causes of hyperhomocysteinemia, there are polymorphisms in the enzymes methylenetetrahydrofolate reductase (C677T) and cystathionine β-synthase (C699T,
Anahi Guadalupe Figueroa-Torres +10 more
doaj +1 more source
Changes in the physical structure and chain dynamics of elastin network in homocysteine-cultured arteries [PDF]
The thermal and dielectric properties of the elastin network were investigated in arteries cultured with physiological and pathological concentrations of homocysteine, an aminoacid responsible of histological impairments in human arteries.
Chareyre, Corinne +6 more
core +2 more sources
Familial hyperhomocysteinemia, age and peripheral vascular diseases - an Italian study
Hyperhomocysteinemia is a widely recognized, although not yet entirely understood, risk factor for cardiovascular disease. Particularly, the complex relationships between age, hyperhomocysteinemia, predisposing genetic factors and peripheral vascular ...
Sandro Michelini +10 more
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Cystathionine beta synthase deficiency and brain edema associated with methionine excess under betaine supplementation: Four new cases and a review of the evidence. [PDF]
CBS deficient individuals undergoing betaine supplementation without sufficient dietary methionine restriction can develop severe hypermethioninemia and brain edema. Brain edema has also been observed in individuals with severe hypermethioninemia without
Barea, Jaime J +10 more
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