Results 51 to 60 of about 26,695 (224)

The Multifaceted Etiology of Mental Disorders With a Focus on Trace Elements, a Review of Recent Literature

open access: yesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Volume 198, Issue 8, Page 168-189, December 2025.
ABSTRACT Mental disorders are a significant global public health concern, affecting nearly one in eight individuals worldwide. This review investigates the multifaceted etiology of mental disorders—specifically major depressive disorder (MDD), schizophrenia (SCZ), and bipolar disorder (BD)—through genetic, neurobiological, and environmental ...
Maria Francesca Astorino   +8 more
wiley   +1 more source

Risk Factors for Cardiovascular and Metabolic Disease: Integrating Traditional and Novel Paradigms

open access: yesiNew Medicine, Volume 1, Issue 1, December 2025.
ABSTRACT Cardiovascular and metabolic diseases (CVMD), encompassing atherosclerotic cardiovascular disease (ASCVD), heart failure, obesity, type 2 diabetes mellitus (T2DM), and metabolic dysfunction‐associated steatotic liver disease (MASLD), remain the leading global cause of morbidity and mortality.
Zhihua Wang   +3 more
wiley   +1 more source

Hyperhomocysteinemia in men with a reproductive history of fetal neural tube defects

open access: yesMedicine, 2019
Rationale: Hereditary hyperhomocysteinemia results from a polymorphism in the methylenetetrahydrofolate reductase (MTHFR) gene that reduces folate metabolism.
Yang Yu   +4 more
semanticscholar   +1 more source

Rewriting the MASLD‐associated hepatocellular carcinoma script: Targeting epigenetics and metabolism

open access: yesInternational Journal of Cancer, Volume 157, Issue 10, Page 1991-2003, 15 November 2025.
Abstract Abnormal epigenetic patterns are crucial for the progression of metabolic‐associated steatotic liver disease (MASLD) and hepatocellular carcinoma (HCC) development. Recent research focused on the interplay between epigenetics and altered metabolic pathways in HCC from MASLD, suggesting that the reversibility of epigenetic changes offers ...
Chiara Aiello   +7 more
wiley   +1 more source

MTHFR Gene Mutations Correlate with White Matter Disease Burden and Predict Cerebrovascular Disease and Dementia

open access: yesBrain Sciences, 2019
The incidence of dementia is on the rise and expected to continue to increase in the foreseeable future. Two of the most common subtypes of dementia are Alzheimer’s subtype and vascular dementia.
Christian E. Cajavilca   +2 more
doaj   +1 more source

Analysis of Risk Factors for Leukoaraiosis: A Multicenter Retrospective Study

open access: yesBrain and Behavior, Volume 15, Issue 11, November 2025.
This study was to analyze the risk factors clinically associated with the development of leukoaraiosis, and to explore clinical biomarkers that may predict leukoaraiosis. The results demonstrate that age, systolic blood pressure, ischemic stroke, and FT4 level serving as factors affecting the development of leukoaraiosis.
Lingqi Sun   +5 more
wiley   +1 more source

Hyperhomocysteinemia, intravascular hemostasis disturbances, and clinical course of myocardial infarction

open access: yesРоссийский кардиологический журнал, 2007
The article is devoted to associations between hyperhomocysteinemia and intravascular hemostasis disturbances in myocardial infarction (MI) patients. The role of these disturbances in post-MI angina and recurrent MI development is analyzed.
V. A. Lusov   +2 more
doaj  

Budd–Chiari Syndrome in the Background of Chronic Kidney Disease: A Hypercoagulability‐Driven Association or Coincidence? A Case Report

open access: yesClinical Case Reports, Volume 13, Issue 11, November 2025.
ABSTRACT Budd–Chiari syndrome (BCS) is a rare condition characterized by hepatic venous outflow obstruction and is often associated with thrombosis or fibrous membranes (webs). To our knowledge, this is the first reported case of BCS occurring secondary to chronic kidney disease (CKD).
Anish Paudyal   +7 more
wiley   +1 more source

Hematinic deficiencies, hyperhomocysteinemia, and gastric parietal cell antibody positivity in atrophic glossitis patients with macrocytosis

open access: yesJournal of the Formosan Medical Association, 2019
Background/Purpose: Macrocytosis is defined as having the mean corpuscular volume (MCV) ≧ 100 fL. This study evaluated whether 41 atrophic glossitis (AG) patients with macrocytosis had significantly higher frequencies of anemia, hematinic deficiencies ...
Chun-Pin Chiang   +5 more
doaj   +1 more source

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