Results 61 to 70 of about 30,982 (276)

Impact of age at first visit on glycolipid metabolism, bone metabolism, and fertility potential in patients with Klinefelter syndrome

Andrology, Volume 14, Issue 1, Page 122-131, January 2026.
Abstract Background Classic Klinefelter syndrome (KS) is characterized by one extra X chromosome (47, XXY), leading to hypergonadotropic hypogonadism and higher risk of alterations in glycolipid homeostasis, cardiovascular diseases, and low bone mineral density. Most frequently, KS is diagnosed in adulthood because of infertility.
Giordana Ferraioli, Andrea Graziani, Noemi Sagone, Andrea Di Nisio, Massimo Iafrate, Fabrizio Dal Moro, Alberto Ferlin, Andrea Garolla   +7 more
wiley   +1 more source

MTHFR Gene Mutations Correlate with White Matter Disease Burden and Predict Cerebrovascular Disease and Dementia

Brain Sciences, 2019
The incidence of dementia is on the rise and expected to continue to increase in the foreseeable future. Two of the most common subtypes of dementia are Alzheimer’s subtype and vascular dementia.
Christian E. Cajavilca, Rajan R. Gadhia, Gustavo C. Román   +2 more
doaj   +1 more source

Does serum gastric parietal cell antibody titer have influence on anemia and vitamin B12 deficiency in atrophic glossitis patients?

Journal of the Formosan Medical Association, 2020
Background/Purpose: Our previous study found 284 gastric parietal cell antibody (GPCA)-positive atrophic glossitis (AG) patients (so-called GPCA+AG patients in this study) in a group of 1064 AG patients.
Chun-Pin Chiang, Yu-Hsueh Wu, Julia Yu-Fong Chang, Yi-Ping Wang, Yang-Che Wu, Andy Sun   +5 more
doaj   +1 more source

Hyperhomocysteinemia in liver transplant recipients: prevalence and multivariate analysis of predisposing factors. [PDF]

, 2000
Liver transplant recipients have an increased risk for cardiovascular disease because of a high incidence of obesity, arterial hypertension, diabetes mellitus, and hyperlipidemia. Hyperhomocysteinemia has been found to be an important risk
Beloqui, O. (Óscar), Herrero, J.I. (José Ignacio), Pardo, F. (Fernando), Prieto, J. (Jesús), Quiroga, J. (Jorge), Sangro, B. (Bruno), Álvarez-Cienfuegos, J. (Javier)   +6 more
core  

Homocysteine Exacerbates Pulmonary Fibrosis via Orchestrating Syntaxin 17 Homocysteinylation of Alveolar Type II Cells

Advanced Science, Volume 12, Issue 46, December 11, 2025.
The study identifies elevated homocysteine (Hcy) levels in idiopathic pulmonary fibrosis patients' samples, with alveolar type 2 cells as the primary site of Hcy metabolism. Methionine synthase reductase downregulation in these cells exacerbates fibrosis, while folate administration reduces Hcy levels and alleviates fibrosis.
Jiefeng Huang, Ke Fang, Wuyan Lu, Rongrong Wu, Yuanyuan Chen, Linxiao Li, Zihao Hu, Zixin Cai, Yu Jiang, Xinli Fan, Jinyi Deng, Guangpeng Liu, Zhuang Luo, Lei Cui, Shuaijun Li   +14 more
wiley   +1 more source

Hyperhomocysteinemia, intravascular hemostasis disturbances, and clinical course of myocardial infarction

Российский кардиологический журнал, 2007
The article is devoted to associations between hyperhomocysteinemia and intravascular hemostasis disturbances in myocardial infarction (MI) patients. The role of these disturbances in post-MI angina and recurrent MI development is analyzed.
V. A. Lusov, A. Yu. Lebedeva, K. V. Mikhailova   +2 more
doaj  

Hyperhomocysteinemia and Endothelial Dysfunction [PDF]

Current Hypertension Reviews, 2009
Hyperhomocysteinemia (HHcy) is a significant and independent risk factor for cardiovascular diseases. Endothelial dysfunction (ED) is the earliest indicator of atherosclerosis and vascular diseases. We and others have shown that HHcy induced ED in human and in animal models of HHcy induced by either high-methionine load or genetic deficiency.
Zhongjian, Cheng, Xiaofeng, Yang, Hong, Wang   +2 more
openaire   +2 more sources

The Multifaceted Etiology of Mental Disorders With a Focus on Trace Elements, a Review of Recent Literature

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Volume 198, Issue 8, Page 168-189, December 2025.
ABSTRACT Mental disorders are a significant global public health concern, affecting nearly one in eight individuals worldwide. This review investigates the multifaceted etiology of mental disorders—specifically major depressive disorder (MDD), schizophrenia (SCZ), and bipolar disorder (BD)—through genetic, neurobiological, and environmental ...
Maria Francesca Astorino, Marco Calabrò, Carmenrita Infortuna, Maria Rosaria Anna Muscatello, Silvana Briuglia, Nicola Cicero, Chiara Fabbri, Alessandro Serretti, Concetta Crisafulli   +8 more
wiley   +1 more source

Significantly higher frequencies of anemia, hematinic deficiencies, hyperhomocysteinemia, and serum gastric parietal cell antibody positivity in atrophic glossitis patients

Journal of the Formosan Medical Association, 2018
Background/Purpose: Atrophic glossitis (AG) patients are prone to have anemia, hematinic deficiencies, hyperhomocysteinemia, and serum gastric parietal cell antibody (GPCA) positivity.
Chun-Pin Chiang, Julia Yu-Fong Chang, Yi-Ping Wang, Yang-Che Wu, Yu-Hsueh Wu, Andy Sun   +5 more
doaj   +1 more source

The Analysis of Asymetric Dimethylarginine and Homocysteine in Patients with Chronic Kidney Disease [PDF]

, 2009
BACKGROUND: Asymmetric dimethylarginine (ADMA) is a competitive inhibitor of nitric oxide synthase (NOS). ADMA reduces NO synthesis when its concentration elevates. ADMA is a novel risk factor for cardiovascular disease.
Arif, M. (Mansyur), Bakri, S. (Syakib), Hendrawati, T. (Tetty)   +2 more
core   +4 more sources