Results 151 to 160 of about 103,854 (365)

Hexosamines Provoke Membrane Cholesterol Accrual, Filamentous Actin Loss, and GLUT4 Dysregulation in Adipocytes through Transcriptional Activation of Specificity Protein 1 [PDF]

, 2012
poster abstractThe hexosamine biosynthesis pathway (HBP) serves as a sensor of excess nutrient bioavailability and has been implicated in the pathogenesis of type 2 diabetes.
Elmendorf, Jeffrey S., Penque, Brent A.
core  

HYPERINSULINEMIA IN TRANSGENIC MICE CARRYING MULTIPLE COPIES OF THE HUMAN INSULIN GENE: EVIDENCE FOR A GENE DOSAGE EFFECT [PDF]

, 1987
Sharon Lee Marbán, John D. Gearhart
openalex   +1 more source

Male LEW.1WR1 Rats Develop Metabolic Dysfunction, Steatohepatitis, and Liver Damage

Endocrines
Most patients with non-alcoholic steatohepatitis (NASH) have insulin resistance, and there is a near-universal association between NASH and insulin resistance.
Quiana C. Wilkerson-Vidal, Madushika M. Wimalarathne, Emily C. Hunt, Luis Mercado, Moses Adaji David, Christopher R. Apperson, Alan Smiley, Sharifa Tahirah Love-Rutledge, Bernhard W. G. Vogler   +8 more
doaj   +1 more source

GLYCOGEN METABOLISM OF FETAL LAMB LUNG IS MODIFIED BY CHRONIC HYPETGLYCEMIA AND HYPERINSULINEMIA [PDF]

, 1984
David Warburton
openalex   +1 more source

Management of pregnancy with metformin: Case reports for genetic insulin resistance syndrome and a literature review for gestational and type 2 diabetes

Journal of Diabetes Investigation, EarlyView.
We here describe perinatal glycemic management with metformin in two women with genetic insulin resistance syndrome caused by variants of the insulin receptor or phosphatidylinositol 3‐kinase (PI3K) genes. In addition, we review the literature related to the efficacy and safety of metformin treatment for gestational diabetes mellitus and type 2 ...
Kai Yoshimura, Yushi Hirota, Tetsushi Hamaguchi, Takehito Takeuchi, Tomofumi Takayoshi, Shuichiro Saito, Mariko Ueda, Seiji Nishikage, Akane Yamamoto, Naoko Hashimoto, Wataru Ogawa   +10 more
wiley   +1 more source

MYOCARDIAL GLYCOGEN METABOLISM IS MODIFIED DURING CHRONIC HYPERGLYCEMIA AND HYPERINSULINEMIA IN THE FETAL LAMB [PDF]

, 1984
David Warburton
openalex   +1 more source

Retrospective analysis of influences of sacubitril/valsartan in patients with diabetes with poorly controlled blood pressure in Japan

Journal of Diabetes Investigation, EarlyView.
Sacubitoril/valsartan vs thiazide in patients with diabetes. ABSTRACT Aims Achieving optimal blood pressure control remains challenging, particularly for patients with diabetes. This post‐hoc study compared the efficacy and safety of switching to sacubitril/valsartan vs adding thiazide diuretics in this population.
Shun Ito, Kazuo Kobayashi, Mari Sotozawa, Kyoji Chiba, Keiichi Chin, Hideo Shimura, Toshinao Tsuge, Hiroyuki Sakai, Takayuki Furuki, Atsushi Matsuzaki, Shinichi Nakajima, Nobukazu Takada, Hareaki Yamamoto, Hiroshi Takeda, Hiromichi Wakui, Takamasa Iwasawa, Togo Aoyama, Kouichi Tamura, Masao Toyoda, Akira Kanamori   +19 more
wiley   +1 more source

SECONDARY FETAL HYPERINSULINEMIA(SFH) IN RAT: NEONATAL GLUCOSE HOMEOSTASIS AND SUBSEQUENT GROWTH [PDF]

, 1987
Chung‐Ja Cha, Gracienda Figueira, Nancy L Gelardi, William Oh   +3 more
openalex   +1 more source

Achilles tenocytes from diabetic and non diabetic donors exposed to hyperglycemia respond differentially to inflammatory stimuli and stretch

Journal of Anatomy, EarlyView.
Scheme depicting the experimental set up of the study. Achilles tendons and tenocytes were isolated from heterozygous (fa/+, non diabetic: non DMT2) and homozygous (fa/fa, diabetic: DMT2) Zucker Diabetic Fatty (ZDF) rats. Tendon degeneration, collagen type 1 alpha 1 chain (COL1A1) and alpha smooth muscle actin (αSMA) expression was determined in rat ...
Nils Fleischmann, Sarah Hofmann, Clemens Gögele, Eva Frank, Christian Werner, Maria Kokozidou, Bernd Hoffmann, Jens Konrad, Gundula Schulze‐Tanzil   +8 more
wiley   +1 more source

Metabolic and Endocrine Insights in Donkeys

Animals
Donkey medicine is gaining attention due to their increased use as companion animals, in shows, asinotherapy, etc. The increasing demand and unique aspects call for specialized care, requiring new information (physiology, infectious disorders ...
Francisco J. Mendoza, Ramiro E. Toribio, Alejandro Perez-Ecija   +2 more
doaj   +1 more source