Results 131 to 140 of about 82,926 (310)

The Bidirectional Association Between MASLD and Male Hypogonadism: An Updated Meta‐Analysis

Andrology, EarlyView.
ABSTRACT Background Metabolic dysfunction‐associated steatotic liver disease (MASLD) and male hypogonadism are increasingly prevalent, metabolically interrelated conditions. Testosterone (T) deficiency has been implicated in hepatic lipid dysregulation, insulin resistance, and visceral adiposity, whereas MASLD may impair the hypothalamic–pituitary ...
Giorgia Spaggiari, Leonardo Dalla Valentina, Cristina Felicani, Filippo Gabrielli, Simonetta Lugari, Giovanni Corona, Paolo Ventura, Manuela Simoni, Fabio Nascimbeni, Daniele Santi   +9 more
wiley   +1 more source

Early‐ vs. late‐onset gestational diabetes: Differential impact on maternal and neonatal outcomes

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Early‐onset gestational diabetes mellitus (diagnosed before 20 weeks) identifies a clinically higher‐risk phenotype than late‐onset GDM (24–28 weeks), with greater insulin requirement and higher adjusted risks of preeclampsia, cesarean delivery, preterm birth, and adverse neonatal outcomes.
Baolai Li, Wenjun Ji, Rui Zhao, Jinchun Zhang   +3 more
wiley   +1 more source

Diabetes and cortical thickness in ethnically diverse cognitively normal older adults

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
INTRODUCTION Mechanisms linking type 2 diabetes mellitus (T2DM) with dementia are poorly understood. We examined T2DM associations with cortical thickness and hippocampal volume in ethnoracially diverse, cognitively unimpaired older adults.
Amaryllis A. Tsiknia, Victoria R. Tennant, Noelle Lee, Brandon J. Hall, Raul Vintimilla, Nalini Hazra, Deydeep Kothapalli, Arthur W. Toga, Sid E. O'Bryant, Rajesh R. Nandy, Alexandra L. Clark, Melissa Petersen, Kristine Yaffe, Meredith N. Braskie, for the HABS‐HD study team   +14 more
doaj   +1 more source

Gestational diabetes in multifetal versus singleton pregnancies: A multicenter cohort study

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Gestational diabetes in multifetal pregnancies was associated with increased maternal morbidity but less adverse neonatal and long‐term offspring outcomes than in singleton pregnancies, suggesting that current diagnostic thresholds derived from singleton gestations may not fully reflect the unique metabolic and clinical characteristics of multifetal ...
Rinat Gabbay‐Benziv, Esther Maor‐Sagie, Amos Stern, Inna Bleicher, Simon Shenhav, Enav Yefet, Yifat Wiener, Michal Kovo, Maya Frank Wolf   +8 more
wiley   +1 more source

Mechanism of hyperinsulinemia after reticuloendothelial system phagocytosis

, 1982
Endocytic loading of the reticuloendothelial system (RES) results in acute hyperinsulinemia and functional hyperinsulinism. Colloidal carbon blockade of the RES in rats resulted in elevations of both portal vein and systemic serum immunoreactive insulin
J. P. Filkins, M. R. Yelich
core   +1 more source

Dysglycaemia and Autonomic Dysfunction: The Diabetes Prevention Program Outcomes Study

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim Limited data on the link between various measures of glycemia and metabolism and autonomic dysfunction exist. We assessed the association of fasting plasma glucose [FPG], glycated haemoglobin [HbA1C], fasting insulin, and HOMA‐IR and cardiac autonomic function measures separately for men and women in the Diabetes Prevention Program ...
Justin B. Echouffo‐Tcheugui, Xun Liu, Elsayed Z. Soliman, Xavier Pi‐Sunyer, Sherita H. Golden, Sam Dagogo‐Jack, Neil H. White, Matthew Budoff, Uzoma Ibebuogu, Christine Darwin, William C. Knowler, Marinella Temprosa, on behalf of the DPP Research Group   +12 more
wiley   +1 more source

Episodic spontaneous hypothermia potentially triggered by hyperinsulinemia

, 2009
Episodic spontaneous hypothermia is an infrequent disorder, the pathogenic mechanisms of which have not been completely clarified, although alterations in the serotoninergic system have been suggested.
Mohn, A., Verrotti, A., Marcovecchio, M. L., Chiarelli, F., Trotta, D., Capanna, R.   +5 more
core   +2 more sources

Vegetable‐First Meal Sequence Suppresses Postprandial Glycaemic Excursions and Variability in Young Women With High‐Risk Phenotype for Early‐Onset Type 2 Diabetes: A 4‐Arm Randomized Crossover Trial With Continuous Glucose Monitoring

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Managing postprandial glycaemic variability is crucial for preventing metabolic diseases. Although the effects of a vegetable‐first meal sequence on blood glucose levels have been well documented, there is limited research on consecutive, repeated meal sequencing for healthy young women.
Minji Choi, Soyoon Lee, Eujean Bang, Ijae Seo, Jieun Lee, Sehyun Joo, Hyeonseo Kim, Song Vogue Ahn, Yuri Kim, Jieun Oh   +9 more
wiley   +1 more source

Male LEW.1WR1 Rats Develop Metabolic Dysfunction, Steatohepatitis, and Liver Damage

Endocrines
Most patients with non-alcoholic steatohepatitis (NASH) have insulin resistance, and there is a near-universal association between NASH and insulin resistance.
Quiana C. Wilkerson-Vidal, Madushika M. Wimalarathne, Emily C. Hunt, Luis Mercado, Moses Adaji David, Christopher R. Apperson, Alan Smiley, Sharifa Tahirah Love-Rutledge, Bernhard W. G. Vogler   +8 more
doaj   +1 more source

Exploratory Analysis of Type 2 Diabetes Mellitus Metabolic Phenotypes and Their Association With Vitamin D Status in Primary Care Patients

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims This study aimed to perform an exploratory characterisation of metabolic phenotypes in primary care patients with type 2 diabetes mellitus (T2DM), using a predefined approach and examine their association with vitamin D status. Materials and Methods This cross‐sectional study included 178 participants randomly selected in Sergipe, Brazil.
Liliane Viana Pires, Matheus Menezes‐Santos, Andréa Costa Goes, Heitor Siqueira Ribeiro, Luana Ferreira Alves, Beatriz Cruz dos Santos, Jéssyca Teles Barreto, Roberta Cristina Vieira Meneses, Ana Mara de Oliveira e Silva, Ana Hermínia Andrade e Silva, Sadraque Eneas de Figueiredo Lucena   +10 more
wiley   +1 more source