Results 111 to 120 of about 82,926 (310)

Taking Into Account Insulin Resistance With Associated Hyperinsulinemia to Counteract the Development of Acute and Chronic Cardiovascular Diseases. [PDF]

Chronic Dis Transl Med
Chronic Diseases and Translational Medicine, Volume 12, Issue 3, Page 264-266, September 2026.
Fazio S, Affuso F.
europepmc   +2 more sources

Epirubicin Alters Pancreatic Autophagy and Insulin Synthesis Through a Zinc‐Dependent Mechanism

Journal of Applied Toxicology, EarlyView.
ABSTRACT Epirubicin (EPI) can cause metabolic side effects, including chemotherapy‐related diabetes, partly through oxidative stress that disrupts zinc (Zn) homeostasis and impairs autophagy. This study investigated the effects of EPI on Zn regulation and autophagy in the pancreas, as well as the modulatory role of N‐acetylcysteine (NAC). Rats received
Ebru Afşar, Işıl Eranıl
wiley   +1 more source

Relationship Between Hyperinsulinemia and Coronary Microvascular Disease [PDF]

Qiang Tan,1 Chenhong Zu,2 Wenli Zhang,1 Jia Hao,2 Yang Li,2 Qiang Lu,3 Zhimeng Li,2 Yao Guo2 1Department of Cardiology, Peking University Third Hospital Qinhuangdao Hospital, Qinhuangdao, Hebei, People’s Republic of China; 2Department of Cardiology, the ...
Zhang W, Li Y, Li Z, Zu C, Hao J, Guo Y, Lu Q, Tan Q   +7 more
core  

Estimated Body Fat Percentage and Triglyceride‐Glucose Index for Identifying MASLD in Lean Asian Adults: A Cross‐Sectional Analysis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) is increasingly prevalent among lean Asian populations, yet effective strategies for identifying high‐risk individuals remain limited. We investigated the associations of body fat percentage (BF%) and the triglyceride‐glucose (TyG) index with lean MASLD and evaluated their ...
Xiang‐Ran Kong, Ya‐Li Chen, Rui Li, Lu‐Xiang Shang, Sha Sha   +4 more
wiley   +1 more source

Hypoglycemia and Hyperinsulinemia in Rodent Models of Severe Malaria Infection [PDF]

, 1994
Severe hypoglycemia developed during nonlethal Plasmodium chabaudi and lethal P. yoelii blood stage malaria infection in mice, always in association with hyperinsulinemia. Supernatants of lethal P.
Playfair, J. H. L., Elased, Khalid M.
core   +2 more sources

Hyperinsulinemia Influences the Short-Term Efficiency of Laparoscopic Sleeve Gastrectomy for Patients with Obesity and Insulin Resistance

Diabetes, Metabolic Syndrome and Obesity, 2023
Zilong Yue,1,* Long Qian,2,* Yan Jin,1,* Yabin Xia,1 Hui Sha,1 Qin Wu,1 Kaifeng Hu1 1Department of Gastrointestinal Surgery, The First Affiliated Yijishan Hospital of Wannan Medical College, Wuhu, Anhui, People’s Republic of China; 2General ...
Yue Z, Qian L, Jin Y, Xia Y, Sha H, Wu Q, Hu K   +6 more
doaj  

Healthy Dietary Patterns and Risk of Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Although healthy dietary patterns have been suggested to be associated with decreased Parkinson's disease (PD) risk, their protective role remains uncertain. Objective To examine associations between eight dietary patterns and PD risk in two United States (US) cohorts followed for up to 32 years.
Xiao Chen, Hui Chen, Peilu Wang, Michael A. Schwarzschild, Albert Y. Hung, Xiang Gao, Alberto Ascherio, Mario H. Flores‐Torres, Kjetil Bjornevik   +8 more
wiley   +1 more source

Mice endometrium receptivity in early pregnancy is impaired by maternal hyperinsulinemia

Molecular Medicine Reports, 2017
Previous studies have investigated the lower embryo implantation rates in women with polycystic ovary syndrome, obesity and type 2 diabetes, and specifically the association between the abnormal oocyte and embryo and hyperinsulinemia.
Runqin Li, Juan Wu, Junlin He, Yingxiong Wang, Xueqing Liu, Xuemei Chen, Chao Tong, Yubin Ding, Yan Su, Wenqi Chen, Chen Zhang, Rufei Gao   +11 more
semanticscholar   +1 more source

Exploring the Reproductive Toxicity of Bisphenol S Through a Network Toxicology and Molecular Docking Analysis

Pediatric Discovery, EarlyView.
Utilizing network toxicology, molecular docking, and dynamic simulations to investigate the potential reproductive toxicity of bisphenol S (BPS). ABSTRACT The aim of this study was to investigate the potential reproductive toxicity of bisphenol S (BPS) and the related molecular mechanisms through a network toxicology approach.
Siyuan Wang, Yan Fu, Xu Huang, Qitong Guo, Xiangqin Zheng, Shengde Wu, Lianju Shen, Guanghui Wei   +7 more
wiley   +1 more source

QSP Modeling Shows Pathological Synergism Between Insulin Resistance and Amyloid‐Beta Exposure in Upregulating VCAM1 Expression at the BBB Endothelium

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 561-571, March 2025.
ABSTRACT Type 2 diabetes mellitus (T2DM), characterized by insulin resistance, is closely associated with Alzheimer's disease (AD). Cerebrovascular dysfunction is manifested in both T2DM and AD, and is often considered as a pathological link between the two diseases.
Zengtao Wang, Vaishnavi Veerareddy, Xiaojiao Tang, Kevin J. Thompson, Sunil Krishnan, Krishna R. Kalari, Karunya K. Kandimalla   +6 more
wiley   +1 more source