Results 101 to 110 of about 82,926 (310)
An Analysis into Metacognition and Family History of Diabetes Mellitus among First Year Medical Students [PDF]
Journal of Clinical and Diagnostic Research, 2017 Introduction: Medical course requires immense effort by the students to deal with vast curriculum and hence, the need to adopt metacognitive skill to cope up. Diabetes mellitus has an impact on cognition. Metacognition, being a component of cognition,
AK Sunitha Priya +3 more
doaj +1 more source
Hyperinsulinemia: a Cause of Obesity?
Current Obesity Reports, 2017 Purpose of ReviewThis perspective is motivated by the need to question dogma that does not work: that the problem is insulin resistance (IR). We highlight the need to investigate potential environmental obesogens and toxins.Recent FindingsThe prequel to ...
K. Erion, B. Corkey
semanticscholar +1 more source
Fetal hyperinsulinemia increases farnesylation of p21 Ras in fetal tissues
, 2001 Even though the role of fetal hyperinsulinemia in the pathogenesis of fetal macrosomia in patients with overt diabetes and gestational diabetes mellitus seems plausible, the molecular mechanisms of action of hyperinsulinemia remain largely enigmatic ...
Boris Draznin +6 more
core +1 more source
New‐Onset Type 2 Diabetes Mellitus and Cancer Risk: A Matched Cohort Study in China Kadoorie Biobank
International Journal of Cancer, EarlyView.ABSTRACT The prevalence of type 2 diabetes mellitus (T2DM) is rising rapidly in China and is linked to increased cancer risk, but causality remains unclear due to biases. We examined the causal effect of T2DM on cancer risk using bias‐minimizing methods.
Mengying Wang +9 more
wiley +1 more source
Gout in pregnancy: Obstetric and neonatal outcomes
International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 349-355, April 2025.Abstract Objective The pregnancy, delivery, and neonatal outcomes of pregnancies complicated by gout have yet to be evaluated in a population‐based study. We sought to evaluate the obstetric and neonatal outcomes in pregnant patients with gout using a national population database.
Sam Amar +3 more
wiley +1 more source
Frontiers in Oncology, 2018 This article presents the first detailed overview of the mechanisms that may underlie the relation of obesity with B-cell non-Hodgkin lymphomas (NHLs) and multiple myeloma (MM).
H. Dean Hosgood +4 more
doaj +1 more source
Nox2 contributes to hyperinsulinemia-induced redox imbalance and impaired vascular function
Redox Biology, 2017 Insulin resistance promotes vascular endothelial dysfunction and subsequent development of cardiovascular disease. Previously we found that skeletal muscle arteriolar flow-induced dilation (FID) was reduced following a hyperinsulinemic clamp in healthy ...
Abeer M. Mahmoud +6 more
semanticscholar +1 more source
Mechanism of the mitogenic influence of hyperinsulinemia [PDF]
, 2011 Either endogenous or exogenous hyperinsulinemia in the setting of insulin resistance promotes phosphorylation and activation of farnesyltransferase, a ubiquitous enzyme that farnesylates Ras protein.
Boris Draznin, Draznin Boris
core +1 more source
ATP Citrate Lyase in Metabolic Disease: Mechanistic Insights and Clinical Potential
iNew Medicine, EarlyView.ATP citrate lyase (ACLY) is a central metabolic hub that diverts mitochondrial citrate to fuel de novo lipogenesis, cholesterol biosynthesis, and protein acetylation. Given its robust correlation with pathological changes in multiple human diseases, ACLY inhibitors featuring distinct pharmacological strengths have been developed for therapeutic ...
Wenbiao Wang +5 more
wiley +1 more source
Caloric restriction in Alstrom syndrome prevents hyperinsulinemia.
, 2009 Alstrom syndrome (AS; OMIM 203800) is an autosomal recessive disorder characterized by cone-rod dystrophy, dilated cardiomyopathy, sensorineural hearing impairment, developmental delay, and most case had both childhood-onset obesity and ...
Jan D. Marshall +13 more
core +2 more sources