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Insights into the molecular and genetic role of obesity in breast cancer pathogenesis. [PDF]
Cancer Biol TherMallya S +6 more
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Severe Insulin Resistance Syndromes: Clinical Spectrum and Management. [PDF]
Int J Mol SciPliszka M, Szablewski L.
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The American Journal of Medicine, 1988
Patients with mild or early non-insulin-dependent diabetes mellitus often display a delay in insulin response followed by late hyperinsulinemia during oral glucose tolerance testing. Those patients with long-standing disease or elevations of fasting plasma glucose in excess of 140 mg/dl are generally hypoinsulinemic in response to an oral glucose ...
R S, Yalow, H G, Rose, W A, Bauman
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Patients with mild or early non-insulin-dependent diabetes mellitus often display a delay in insulin response followed by late hyperinsulinemia during oral glucose tolerance testing. Those patients with long-standing disease or elevations of fasting plasma glucose in excess of 140 mg/dl are generally hypoinsulinemic in response to an oral glucose ...
R S, Yalow, H G, Rose, W A, Bauman
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Hyperinsulinemia in patients with hypercholesterolemia
Journal of Clinical Endocrinology & Metabolism, 1992An independent association between hypercholesterolemia and high insulin levels has not consistently emerged from large-scale epidemiologic observations. We selected 39 patients with elevated low-density (LDL) cholesterol levels but normal body weight, blood pressure, and glucose tolerance, and compared them to 36 normocholesterolemic, healthy control ...
PAOLISSO, Giuseppe +4 more
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Insulin Resistance and Hyperinsulinemia
Diabetes Care, 2008Insulin resistance, recently recognized as a strong predictor of disease in adults, has become the leading element of the metabolic syndrome and renewed as a focus of research. The condition exists when insulin levels are higher than expected relative to the level of glucose. Thus, insulin resistance is by definition tethered to hyperinsulinemia.
Rachel Dankner +5 more
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Mechanism of hyperinsulinemia in endotoxicosis
American Journal of Physiology-Endocrinology and Metabolism, 1980Hyperinsulinemia subsequent to endotoxemia is a key factor leading to the disturbance of glucose homeostasis in endotoxin shock. This study investigated the mechanism(s) of hyperinsulinemia during endotoxicosis in the rat. Two primary mechanisms for the hyperinsulinemia were evaluted: 1) decreased removal of insulin by the endotoxic liver, and 2 ...
M. R. Yelich, J. P. Filkins
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Hyperinsulinemia in hyperthecosis of the ovaries
American Journal of Obstetrics and Gynecology, 1986Fasting insulin concentrations and the insulin response to an oral glucose tolerance test were measured in six virilized women with ovarian hyperthecosis and six weight-matched normal women. For comparison, six women with polycystic ovarian disease were also studied.
Tung Van Dinh +2 more
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BMI and hyperinsulinemia in children
Clinical Biochemistry, 2009Overweight is associated with hyperinsulinemia in adults and children. The aim of our study was to test if body mass index (BMI) alone or in combination with waist circumference (WC) predicts hyperinsulinemia in individual children.In 466 healthy German schoolchildren aged 7 to 12 years enrolled in the population based PEP Family Heart Study ...
Michael Lehrke +6 more
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Hypertension and Hyperinsulinemia
Primary Care: Clinics in Office Practice, 1991Hypertension may be either accentuated or caused by hyperinsulinemia secondary to insulin resistance. The role of hyperinsulinemia has been most clearly defined in those people with upper body obesity who frequently have hypertension, abnormal glucose tolerance, and dyslipidemia.
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Hyperinsulinemia and Atherosclerosis
Diabetes, 1996For more than 25 years, there has been an expansion in the clinical and experimental evidence linking hyperinsulinemia with cardiovascular disease and atherosclerosis. Assessment of the evidence under the headings of the strength of the association, dose response, temporality, consistency, specificity, and plausibility supports the concept that ...
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