Obesity and the gut microbiota: implications of neuroendocrine and immune signaling
The FEBS Journal, Volume 292, Issue 6, Page 1397-1420, March 2025.An unhealthy diet impairs the symbiotic relationship between the gut microbiota and the host, contributing to obesity. At the intestinal level, identification of host–microbe events essential for proper neuroendocrine/immune signaling is key to the development of microbiome‐based strategies to promote metabolic health in obesity (probiotics ...
Marina Romaní‐Pérez +6 more
wiley +1 more source
Revista Cubana de Endocrinología, 2006 Aunque Gerald M. Reaven describió en 1988 el síndrome X, múltiples nombres ha recibido este con el decursar del tiempo. Los de mayor aceptación son: síndrome metabólico (SM) y síndrome de insulinorresistencia (SIR).
Raúl Orlando Calderín Bouza +1 more
doaj
Phthalate and gallstones: the mediation of insulin
Frontiers in Public HealthBackgroundExposure to a mixture of environmental chemicals may cause gallstone, but the evidence remains equivocal. The current study aims to investigate the association between phthalate metabolites and gallstones, and to explore their mediators ...
Haoxian Tang +14 more
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HYPERINSULINEMIA IN TRANSGENIC MICE CARRYING MULTIPLE COPIES OF THE HUMAN INSULIN GENE: EVIDENCE FOR A GENE DOSAGE EFFECT [PDF]
, 1987 Sharon Lee Marbán, John D. Gearhart
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The universal role of adaptive transcription in health and disease
The FEBS Journal, EarlyView.Adaptive transcription via molecules such as CREB, MEF2, SRF, AP1, Nr4a1, and Egr1 constitutes a universal mechanism for directed cell state transitions in health and disease. These molecules are involved in physiological adaptation processes, pathological maladaptations, curative adaptations, and development of resistance to treatment.
Thomas Lissek
wiley +1 more source
Diabetes Mellitus and Reprogrammed Glucose Metabolism in Pancreatic Cancer: Features for Clinical Translation [PDF]
, 2016 The reprogrammed metabolism of cancer cells underlies the shift of glucose energetics from the highly efficient oxidative phosphorylation to the less efficient aerobic glycolysis, the Warburg effect.
BASSO, DANIELA +4 more
core
GLYCOGEN METABOLISM OF FETAL LAMB LUNG IS MODIFIED BY CHRONIC HYPETGLYCEMIA AND HYPERINSULINEMIA [PDF]
, 1984 David Warburton
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Stbd1 stimulates AMPK signaling and alleviates insulin resistance in an in vitro hepatocyte model
The FEBS Journal, EarlyView.Stbd1 is an N‐myristoylated, ER‐resident, glycogen‐binding protein whose loss‐of‐function has been associated with insulin resistance. We report that AML12 hepatocytes overexpressing either N‐myristoylated Stbd1 or a non‐N‐myristoylated variant display enhanced AMPK signaling and improved insulin sensitivity, independently of differences in glycogen ...
Andria Theodoulou +8 more
wiley +1 more source
The Seasonality of Serum Insulin Concentrations in Equids and the Association With Breed, Age, and Sex. [PDF]
J Vet Intern MedABSTRACT Background Current laboratory reference values for serum insulin concentrations do not account for seasonal fluctuations and differences associated with breed, sex, and age. Hypothesis We hypothesized that serum insulin concentrations would differ with the season, breed, sex, and age. Animals Laboratory records from 21 236 cases. Methods Cases
Lopes A, Huber L, Durham AE.
europepmc +2 more sources
MYOCARDIAL GLYCOGEN METABOLISM IS MODIFIED DURING CHRONIC HYPERGLYCEMIA AND HYPERINSULINEMIA IN THE FETAL LAMB [PDF]
, 1984 David Warburton
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