Results 231 to 240 of about 82,926 (310)

Machine learning‐based prediction model for adverse pregnancy outcomes in women with gestational diabetes mellitus

Journal of Diabetes Investigation, Volume 17, Issue 9, Page 1583-1590, September 2026.
Machine learning models were developed in Korean women with gestational diabetes to predict adverse pregnancy outcomes including large‐ and small‐for‐gestational‐age, low Apgar score, and preterm delivery. RandomForest and ExtraTree showed highest AUROC 0.726 for LGA and 0.689 for low Apgar score, respectively.
Jooyeop Lee, Seoung‐Ho Choi, Hyeon Ji Kim, Jee Yoon Park, Tae Jung Oh, Sung Hee Choi, Hak Chul Jang, Joon Ho Moon   +7 more
wiley   +1 more source

Associations of finerenone with reduced insulin resistance in patients with type 2 diabetes and chronic kidney disease: A real‐world observational study

Journal of Diabetes Investigation, Volume 17, Issue 9, Page 1524-1532, September 2026.
This real‐world observational study enrolled 256 patients with type 2 diabetes and chronic kidney disease (T2D‐CKD). After 12 months of finerenone treatment, 45 patients completed follow‐up. Finerenone was associated with significant improvements in insulin resistance markers (HOMA‐IR, TyG index), lipid profile (LDL‐C), glycemic control (HbA1c), and ...
Xin Zhao, Bohan Liu, Ran Sun, Yaxuan Shi, Ya Liu   +4 more
wiley   +1 more source

Hypertriglyceridemic waist: A marker of the atherogenic metabolic triad (hyperinsulinemia; hyperapolipoprotein B; small, dense LDL) in men?

Circulation, 2000
I. Lemieux, A. Pascot, C. Couillard, B. Lamarche, A. Tchernof, N. Alméras, J. Bergeron, D. Gaudet, G. Tremblay, D. Prud'homme, A. Nadeau, J. Despres   +11 more
semanticscholar   +1 more source

Reductive Stress and Ferroptosis: Linking Insulin Signaling to Metabolic Dysfunction. [PDF]

Biomolecules
Karunakaran U, Elumalai S.
europepmc   +1 more source

Acute effects of hyperinsulinemia and hyperglycemia on vascular inflammatory biomarkers and endothelial function in overweight and obese humans.

American Journal of Physiology. Endocrinology and Metabolism, 2015
J. Perkins, N. Joy, Donna B. Tate, S. N. Davis   +3 more
semanticscholar   +1 more source

Early diagnosis of gestational diabetes mellitus evidence from Asia countries: A meta‐analysis and systematic review

Journal of Diabetes Investigation, Volume 17, Issue 9, Page 1591-1603, September 2026.
In Asian populations, early gestational diabetes mellitus (diagnosed before 24 weeks) identifies women at higher metabolic risk and is associated with increased insulin use, preterm birth, and operative delivery. These findings support the need for harmonized diagnostic criteria and region‐specific screening strategies.
Ke Thi Lan Anh, Nguyen Ngoc Anh, Pham Minh Nguyet, Dang Phuong Linh, Tran Thi Hai Yen, Vo Duy Quan   +5 more
wiley   +1 more source

A sweet danger: the silent link between hyperinsulinemia and gastric cancer. [PDF]

Mol Cancer
Laurenziello P, Luongo M, Lospinoso Severini F, Russi S, Falco G, Calabrese C, Laurino S.   +6 more
europepmc   +1 more source

Efficacy and Safety of Bariatric Surgery in Acquired Hypothalamic Obesity: A Systematic Review and Individual Patient Data Meta‐Analysis

Obesity Reviews, Volume 27, Issue 9, September 2026.
ABSTRACT Objective This work aimed to investigate the efficacy and safety of Roux‐en‐Y gastric bypass (RYGB) and sleeve gastrectomy (SG) in adults with acquired hypothalamic obesity (HO). Design Systematic review and meta‐analysis. Methods Publications reporting relevant outcomes in patients with HO before and after RYGB or SG were identified through a
Johannes Fessler, Pauline Faucher, Christine Poitou, Carsten Dirksen   +3 more
wiley   +1 more source

Why hyperinsulinemia is detrimental to weight loss: insights from type 1 diabetes. [PDF]

BMC Med
Martin S, Kempf K, Kolb H.
europepmc   +1 more source

Cardiometabolic Multimorbidity Increases the Risk of Hip Fracture: A Longitudinal Cohort Study Based on CHARLS

Orthopaedic Surgery, Volume 18, Issue 9, Page 1916-1927, September 2026.
CMM increase the risk of hip fracture, especially in relatively younger individuals and participants with a history of falls. From the perspective of CMM, controlling the number of chronic conditions is expected to block the risk–amplifying effect of multimorbidity on hip fracture and reduce the cost of intervention. ABSTRACT Background Cardiometabolic
Peng Tian, Shaoxiong Du, Run Tian, Weidong Zhu, Chunsheng Wang, KunZheng Wang, Pei Yang, Xin Huang   +7 more
wiley   +1 more source