Results 241 to 250 of about 82,926 (310)

Metabolic and Signaling Dysregulation in a Cellular Model of Hepatic Insulin Resistance. [PDF]

Curr Issues Mol Biol
Zbeeb H, Joumaa C, De Negri Atanasio G, Diaspro A, Vergani L.   +4 more
europepmc   +1 more source

Hyperinsulinemia drives diet-induced obesity independently of brain insulin production.

Cell Metabolism, 2012
A. Mehran, N. Templeman, G. Stefano Brigidi, Gareth E. Lim, K. Chu, Xiaoke Hu, J. D. Botezelli, A. Asadi, B. Hoffman, T. Kieffer, S. Bamji, S. M. Clee, James D. Johnson   +12 more
semanticscholar   +1 more source

Sensitive Period Analysis of Adulthood BMI and Cancer Risk: An Individual Participant Data Meta‐Analysis of Over 720,000 Participants in the ABACus 2 Consortium

International Journal of Cancer, Volume 159, Issue 4, Page 960-972, 15 August 2026.
Over a dozen cancers have been associated with excess body mass index, primarily in mid‐to‐late adulthood. Whether obesity‐related cancer risk differs across adulthood remains unclear. Using the Sensitive Periods Model and super‐landmarking approaches, this study found that higher BMI increased obesity‐related cancer risk across ages 30–65.
Nadin K. Hawwash, Matthew Sperrin, Glen P. Martin, Rashmi Sinha, Charles E. Matthews, Matthias B. Schulze, Anouk Hiensch, Pilar Amiano, Marian L. Neuhouser, Corinne E. Joshu, Elizabeth A. Platz, Heinz Freisling, Marc J. Gunter, Andrew G. Renehan   +13 more
wiley   +1 more source

Differential Pathophysiological Drivers of Susceptibility to Type 2 Diabetes and Metabolic Dysfunction-Associated Steatotic Liver Disease: Ethnic Differences in Insulin Dynamics, Whole-Body Fat Metabolism, and Organ-Specific Lipid Deposition. [PDF]

Obes Rev
Cuthbertson DJ, Whyte M, Henney AE, Alam U, Goff L, Fielding BA, Umpleby AM.   +6 more
europepmc   +1 more source

GLP-1 Secretion Is Increased by Inflammatory Stimuli in an IL-6–Dependent Manner, Leading to Hyperinsulinemia and Blood Glucose Lowering

Diabetes, 2014
F. Kahles, Christina Meyer, J. Möllmann, S. Diebold, Hannes M. Findeisen, C. Lebherz, C. Trautwein, A. Koch, F. Tacke, N. Marx, M. Lehrke   +10 more
semanticscholar   +1 more source

MASLD as Complication of Diabetes. [PDF]

Diabetes
Stefan N.
europepmc   +1 more source

Hyperinsulinemic hypoglycemia in renal glucosuria in the presence of a novel sodium-glucose cotransporter 2 variant. [PDF]

JCEM Case Rep
Cadogan S, Madden A, O'Dwyer O, Kavanagh K, O'Byrne JJ, Byrne MM.   +5 more
europepmc   +1 more source

Is high insulin protective or detrimental? Mathematical modeling reveals the base of the iceberg. [PDF]

Am J Physiol Endocrinol Metab
Yang B, Ha J, Sherman AS.
europepmc   +1 more source

Understanding the mechanisms underlying obesity induced tumorigenesis: therapeutic perspectives to manage dysregulated lipid metabolism. [PDF]

Discov Oncol
Faridi U, Mir R, Algehainy NA, Alharbi ZM, Tayeb FJ, Barnawi J, Jalal MM, Altayar MA, Moawadh M, Mustafa SK, Mir MM, Alfaifi J, Almazni IA.   +12 more
europepmc   +1 more source

Editorial: Addressing insulin resistance and hyperinsulinemia for cardiovascular disease prevention. [PDF]

Front Cardiovasc Med
Fazio S, Pucci G, Tibullo L, Fazio V, Mercurio V.   +4 more
europepmc   +1 more source