Results 241 to 250 of about 103,854 (365)

Hyperglycemia‐ and hyperinsulinemia‐induced insulin resistance causes alterations in cellular bioenergetics and activation of inflammatory signaling in lymphatic muscle

The FASEB Journal, 2017
Yang Lee, J. Fluckey, Sanjukta Chakraborty, M. Muthuchamy   +3 more
semanticscholar   +1 more source

Hyperinsulinemia in Polycystic Ovary Syndrome [PDF]

Journal of Medical Science And clinical Research, 2017
P. Lekshmi Ammal, S.Krishnadas
openaire   +1 more source

Maternal high fat and high sugar diet impacts on key DNA methylation enzymes in offspring brain in a sex‐specific manner

Journal of Neuroendocrinology, Volume 37, Issue 8, August 2025.
Abstract Maternal obesity associates with an increased risk of offspring neurodevelopmental disorders. Although the underlying mechanism(s) remain unclear, evidence suggests a role for altered DNA methylation. We utilized a murine model of diet‐induced obesity to investigate the impact of maternal obesity on the offspring brain transcriptome and DNA ...
Kahyee Hor, Laura Dearden, Emily Herzstein, Susan Ozanne, Giles Hardingham, Amanda J. Drake   +5 more
wiley   +1 more source

Reappraising the relationship between hyperinsulinemia and insulin resistance in PCOS. [PDF]

J Endocrinol
Houston EJ, Templeman NM.
europepmc   +1 more source

Effect of hyperinsulinemia and hyperglycemia on proximal gastric motor function

, 1998
A.S. van Petersen, M. K. Vu, WK Lam, C. B. H. W. Lamers, Jan Ringers, Ad Masclee   +5 more
openalex   +1 more source

Syndrome W: a new model of hyperinsulinemia, hypertension and other CAD risk factors in healthy midlife women with normal glucose tolerance [PDF]

, 1999
Harriette R. Mogul, Brant M. Weinstein, Douglas Mogul   +2 more
openalex   +1 more source

Kir6.2 channel activity is regulated by interaction of transmembrane domains 1 and 2 through I167 in the bundle‐crossing gate

Physiological Reports, Volume 13, Issue 15, August 2025.
Abstract ATP‐sensitive potassium (KATP) channel in pancreatic β‐cells is composed of four pore‐forming inward rectifier potassium (Kir) 6.2 subunits and four regulatory sulfonylurea receptor (SUR) 1 subunits and regulate insulin secretion. Kir6.2 consists of a N‐terminal region, an outer transmembrane helix (TM1), an intramembrane region that functions
Ryoko Kawashima, Charlotte Meller, Manabu Suzuki, Shigeki Kato, Shoichiro Horita, Shizu Hidema, Shingen Misaka, Mitsuaki Hosoya, Hayato Go, Kazuto Kobayashi, Heidi de Wet, Yuko Maejima, Kenju Shimomura   +12 more
wiley   +1 more source

Sustained Metabolic Improvements with Low-Dose Metformin Combined with Oral Contraceptives in Female Adolescents with PCOS: A Single-Center Retrospective Cohort Study. [PDF]

Adv Ther
Vitale SG, Di Michele S, Tassi A, Succu C, Angioni S, Fulghesu AM.   +5 more
europepmc   +1 more source

Effects of Hyperinsulinemia on Plasma Levels of Circulating Adhesion Molecules [PDF]

, 2000
B. Jilma
openalex   +1 more source

Moderate‐intensity aerobic exercise attenuates obesity‐induced changes in perivascular adipose tissue in female mice

Physiological Reports, Volume 13, Issue 16, August 2025.
Aerobic exercise attenuates obesity‐induced tPVAT dysfunction by reducing inflammation, oxidative stress, and restoring anti‐contractile vascular response in female mice. Abstract The goal of the study was to investigate the effects of aerobic exercise training on inflammatory, oxidative stress, and cellular senescence biomarkers, along with the ...
Teresa M. Da‐Re, Guilherme A. dos Santos, Luiza H. Rossi, Camila B. Risso, Sílvio R. Consonni, Maria A. Delbin   +5 more
wiley   +1 more source