Results 121 to 130 of about 20,887 (300)

Association of polymorphism genes LPL, ADRB2, AGT and AGTR1 with risk of hyperinsulinism and insulin resistance in the Kazakh population

open access: yesBiomedical Reports, 2020
Hyperinsulinism and insulin resistance are closely associated with several common diseases including type 2 of diabetes, cardiovascular diseases, and metabolic syndrome.
A. Shakhanova   +6 more
semanticscholar   +1 more source

Safety and Efficacy of DTX401, an AAV8‐Mediated Liver‐Directed Gene Therapy, in Adults With Glycogen Storage Disease Type I a (GSDIa)

open access: yesJournal of Inherited Metabolic Disease, Volume 48, Issue 2, March 2025.
ABSTRACT Glycogen storage disease type Ia (GSDIa) is a rare, life‐threatening, inherited carbohydrate metabolism disorder caused by glucose‐6‐phosphatase (G6Pase) deficiency, which is essential for glycogenolysis and gluconeogenesis. GSDIa management includes a strict medically prescribed diet that typically includes daily uncooked cornstarch doses ...
David A. Weinstein   +18 more
wiley   +1 more source

The Development of a Direct Homologous Radioimmunoassay for Serum Cortisol [PDF]

open access: yes, 1981
Peer ...
Giesemann, G.   +4 more
core   +2 more sources

Neonatal cardiac hypertrophy: the role of hyperinsulinism—a review of literature

open access: yesEuropean Journal of Pediatrics, 2019
Hypertrophic cardiomyopathy (HCM) in neonates is a rare and heterogeneous disorder which is characterized by hypertrophy of heart with histological and functional disruption of the myocardial structure/composition.
N. D. Paauw   +5 more
semanticscholar   +1 more source

Managing Hypoglycaemia in Patients With Insulinoma—A Tertiary Centre Experience and Review of the Literature

open access: yesClinical Endocrinology, Volume 102, Issue 3, Page 344-354, March 2025.
ABSTRACT The management of hypoglycaemia is pivotal in the care of patients with insulinoma. Blood glucose monitoring and regulation needs careful attention pre‐ and peri‐operatively for patients undergoing surgical resection and as part of the long‐term management for patients with inoperable or metastatic disease.
Sophie Howarth   +3 more
wiley   +1 more source

Estudio PET-TC con 18F-fluoro-L-DOPA combinado con el análisis genético para la optimización de la clasificación y tratamiento de un niño con hiperinsulinismo congénito grave [PDF]

open access: yes, 2009
BACKGROUND: Congenital hyperinsulinism (CHI) is the most common cause of persistent hypoglycaemia in infancy. The differential diagnosis between focal and diffuse forms of CHI is of great importance when planning surgery. The aim of this article is to
Arbizu, J. (Javier)   +6 more
core  

The treatment of hyperinsulinemic hypoglycaemia in adults: an update [PDF]

open access: yes, 2016
Treatment of hyperinsulinemic hypoglycaemia (HH) is challenging due to the rarity of this condition and the difficulty of differential diagnosis.
A. Colao   +6 more
core   +1 more source

Prevalence of Adverse Events in Children With Congenital Hyperinsulinism Treated With Diazoxide

open access: yesJournal of Clinical Endocrinology and Metabolism, 2018
Context Diazoxide, the only U.S. Food and Drug Administration-approved drug to treat hyperinsulinemic hypoglycemia, has been associated with several adverse events, which has raised concerns about the safety of this drug.
A. Herrera   +6 more
semanticscholar   +1 more source

Congenital hyperinsulinism with hyperammonaemia

open access: yesBMJ Case Reports, 2010
Congenital hyperinsulinism is considered to be the most frequent cause of persistent recurrent hypoglycaemia in infants. The clinical presentation and response to pharmacological treatment may vary significantly depending on the underlying pathology. We report a case of a female infant with mild but early onset of recurrent hypoglycaemia.
Hubert Fahnenstich   +2 more
openaire   +4 more sources

Insulin Autoimmune Syndrome: A Chinese Expert Consensus Statement

open access: yesAGING MEDICINE, Volume 8, Issue 1, February 2025.
ABSTRACT Insulin autoimmune syndrome (IAS) is a rare autoimmune disorder characterized by spontaneous hypoglycemia. The incidence of IAS is higher in East Asian populations compared to other populations. Delayed diagnosis and treatment can lead to recurrent hypoglycemia, significant glucose fluctuations, and adverse clinical outcomes, including life ...
Huabing Zhang, Ming Xia Yuan, Qi Pan
wiley   +1 more source

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