Results 161 to 170 of about 16,326 (211)

Hyperinsulinism

New England Journal of Medicine, 1933
Hyperinsulinism is the term suggested by Harris 1 in 1924 in explanation of spontaneous hypoglycemia. If there is insufficient insulin, hyperglycemia and diabetes mellitus develop; if insulin is excessive, hypoglycemia develops, with the characteristic symptoms seen after an overdose of insulin.
E. STARR JUDD   +2 more
  +5 more sources

Congenital hyperinsulinism

Early Human Development, 2010
Congenital hyperinsulinism (CHI or HI) is a condition leading to recurrent hypoglycemia due to an inappropriate insulin secretion by the pancreatic islet beta cells. HI has two main characteristics: a high glucose requirement to correct hypoglycemia and a responsiveness of hypoglycemia to exogenous glucagon.
Jean-Baptiste, Arnoux   +15 more
openaire   +2 more sources

Neonatal Hyperinsulinism

Clinics in Perinatology, 1998
Hyperinsulinism is the most frequent cause of severe, persistent hypoglycemia in neonates and young infants. Timely diagnosis and aggressive treatment are necessary to prevent long-term neurologic sequelae. This article explores the latest advances in the understanding of the pathophysiology of this disorder at the molecular and cellular level.
V M, Schwitzgebel, S E, Gitelman
openaire   +2 more sources

Congenital Hyperinsulinism

NeoReviews, 2021
Hyperinsulinemic hypoglycemia (HH) is fairly common in neonates, particularly those born to diabetic mothers and those who are either large or small for gestational age. Immediate management of the disease focuses on achieving normoglycemia through frequent high-calorie feedings and/or intravenous glucose administration.
openaire   +2 more sources

Congenital Hyperinsulinism

Pediatric Annals, 2017
Congenital hyperinsulinism is a rare disorder that commonly presents in the immediate postnatal period as persistent hypoglycemia. The condition is frequently resistant to medical therapies, and the genetic mutations implicated in the disorder can be predictive of response to therapy.
Elena, Minakova, Alison, Chu
openaire   +2 more sources

Neonatal Hyperinsulinism

Trends in Endocrinology & Metabolism, 1999
Hypoglycemia as a result of hyperinsulinism in the newborn (HI) is a clinically heterogeneous entity that presents a diagnostic and therapeutic challenge to the treating physician. Recent discoveries have shown that mutations in four different beta-cell genes cause HI.
, Glaser, , Landau, , Permutt
openaire   +2 more sources

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