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Current Opinion in Pediatrics, 2013
Congenital hyperinsulinism (CHI) is a multifaceted disease and continues to be the most common cause of persistent hypoglycemia in infants. The purpose of the review is to highlight important recent developments regarding CHI.Several recent studies have highlighted the advances in medical genetics, imaging techniques, histological variety, and surgical
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Congenital hyperinsulinism (CHI) is a multifaceted disease and continues to be the most common cause of persistent hypoglycemia in infants. The purpose of the review is to highlight important recent developments regarding CHI.Several recent studies have highlighted the advances in medical genetics, imaging techniques, histological variety, and surgical
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Seminars in Fetal and Neonatal Medicine, 2005
Congenital hyperinsulinism is a cause of persistent hypoglycaemia in the neonatal period. It is a heterogeneous disease with respect to clinical presentation, molecular biology, genetic aetiology and response to medical therapy. The clinical heterogeneity may range from severe life-threatening disease to very mild clinical symptoms.
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Congenital hyperinsulinism is a cause of persistent hypoglycaemia in the neonatal period. It is a heterogeneous disease with respect to clinical presentation, molecular biology, genetic aetiology and response to medical therapy. The clinical heterogeneity may range from severe life-threatening disease to very mild clinical symptoms.
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Archives of Internal Medicine, 1929
Since the introduction of insulin in treatment, the symptoms of hypoglycemia have become well known. Many cases are being recognized in which hypoglycemia occurs spontaneously. As a rule, the symptoms are mild, but in a small number of cases they have been severe.
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Since the introduction of insulin in treatment, the symptoms of hypoglycemia have become well known. Many cases are being recognized in which hypoglycemia occurs spontaneously. As a rule, the symptoms are mild, but in a small number of cases they have been severe.
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Annals of Pharmacotherapy, 1997
In a limited number of case reports in infants, octreotide raised the blood glucose concentrations and decreased glucose requirements sufficiently to avoid pancreatectomy. This response occurs in the presence of frequent feedings and diazoxide therapy, and lasts from 1 month to greater than 5 years.
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In a limited number of case reports in infants, octreotide raised the blood glucose concentrations and decreased glucose requirements sufficiently to avoid pancreatectomy. This response occurs in the presence of frequent feedings and diazoxide therapy, and lasts from 1 month to greater than 5 years.
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Archives of Internal Medicine, 1937
The primary purpose of this paper is to record the subsequent progress and necropsy observations in the case of hyperinsulinism previously reported on.1In addition, mention will be made of special studies in regard to the phosphate content of the blood, psychomotor tests and the sugar content and pressure of the spinal fluid.
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The primary purpose of this paper is to record the subsequent progress and necropsy observations in the case of hyperinsulinism previously reported on.1In addition, mention will be made of special studies in regard to the phosphate content of the blood, psychomotor tests and the sugar content and pressure of the spinal fluid.
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SUR1-mutant iPS cell-derived islets recapitulate the pathophysiology of congenital hyperinsulinism
Diabetologia, 2021Väinö Lithovius +2 more
exaly