Results 11 to 20 of about 16,326 (211)
Endocrines, 2022 Congenital or monogenic hyperinsulinism (HI) is a group of rare genetic disorders characterized by dysregulated insulin secretion and is the most common cause of persistent hypoglycemia in children. Knowledge of normal glucose homeostasis allows for a better understanding of the underlying pathophysiology of hyperinsulinemic hypoglycemia, facilitating ...
Ethel Gonzales Clemente +3 more
openaire +2 more sources
Brain injury due to persistent hyperinsulinemic hypoglycemia of infancy [PDF]
, 2007 A
De Visschere, Pieter +3 more
core +2 more sources
Expression and function of ATP-dependent potassium channels in zebrafish islet β-cells [PDF]
, 2017 ATP-sensitive potassium channels (K(ATP) channels) are critical nutrient sensors in many mammalian tissues. In the pancreas, K(ATP) channels are essential for coupling glucose metabolism to insulin secretion.
Conway, Hannah +8 more
core +2 more sources
Hyperinsulinism assessment in a sample of prepubescent children [PDF]
, 2010 OBJECTIVES: To determine the relationship between body mass index (BMI), homeostasis model assessment - insulin resistance (HOMA-IR) and insulinemia. METHODS: This was a prospective cross-sectional observational study of 132 prepubescent schoolchildren ...
Azzalis, Ligia Ajaime +5 more
core +8 more sources
Tissue Sodium Content and Arterial Hypertension in Obese Adolescents [PDF]
, 2019 Early-onset obesity is known to culminate in type 2 diabetes, arterial hypertension and subsequent cardiovascular disease. The role of sodium (Na+) homeostasis in this process is incompletely understood, yet correlations between Na+ accumulation and ...
Berger, Felix +12 more
core +3 more sources
Nifedipine in Congenital Hyperinsulinism - A Case Report. [PDF]
, 2016 PublishedJournal ArticleThis is the final version of the article. Available from Galenos Yayınevi via the DOI in this record.Congenital hyperinsulinism (CHI) is the commonest cause of persistent hypoglycemia in neonates.
Basak, D +4 more
core +1 more source
Medicina, 2014 Hyperinsulinism is the most common cause of hypoglycemia in infants. In many cases conservative treatment is not effective and surgical intervention is required. Differentiation between diffuse and focal forms and localization of focal lesions are the most important issues in preoperative management.
Indrė Petraitienė +6 more
openaire +3 more sources
Clinical and molecular data from 61 Brazilian cases of Congenital Hyperinsulinemic Hypoglycemia [PDF]
, 2015 Objective: To study the clinical and molecular characteristics of a sample of Brazilian patients with Congenital Hyperinsulinemic Hypoglycemia (CHH).Methods: Electronic message was sent to members from Endocrinology Department-Brazilian Society of ...
Della Manna, Thais +5 more
core +3 more sources
A new familial form of a late-onset, persistent hyperinsulinemic hypoglycemia of infancy caused by a novel mutation in KCNJ11. [PDF]
, 2017 The ATP-sensitive potassium channel (KATP) functions as a metabo-electric transducer in regulating insulin secretion from pancreatic β-cells. The pancreatic KATP channel is composed of a pore-forming inwardly-rectifying potassium channel, Kir6.2, and a ...
Ferrara, Christine +5 more
core +1 more source
A combination of nifedipine and octreotide treatment in an hyperinsulinemic hypoglycemic infant. [PDF]
, 2016 PublishedResearch Support, Non-U.S. Gov'tThis is the final version of the article. Available from Galenos Publishing via the DOI in this record.Hyperinsulinemic hypoglycemia (HH) is the commonest cause of persistent hypoglycemia in the neonatal and ...
Akcurin, S +5 more
core +1 more source