Results 11 to 20 of about 20,640 (292)
Genetics of neonatal hyperinsulinism [PDF]
Archives of Disease in Childhood - Fetal and Neonatal Edition, 2000 Congenital hyperinsulinism (HI) is a clinically and genetically heterogeneous entity. The clinical heterogeneity is manifested by severity ranging from extremely severe, life threatening disease to very mild clinical symptoms, which may even be difficult to identify.
Benjamin Gläser +3 more
openalex +4 more sources
Avaliação do hiperinsulinismo em amostra de crianças pré-puberes Hyperinsulinism assessment in a sample of prepubescent children [PDF]
Jornal de Pediatria, 2010 OBJETIVOS: Determinar a relação entre o índice de massa corporal (IMC), o homeostasis model assessment - insulin resistance (HOMA-IR) e a insulinemia. MÉTODOS: Realizou-se um estudo observacional prospectivo transversal com 132 crianças pré-púberes em ...
Stephanye Felicye Armecy Mieldazis +5 more
doaj +7 more sources
Hyperinsulinism and atherogenesis. [PDF]
BMJ, 1971 John Yudkin, Stephen Szanto
openalex +5 more sources
International Guidelines for the Diagnosis and Management of Hyperinsulinism
Hormone Research in Paediatrics, 2023 Background: Hyperinsulinism (HI) due to dysregulation of pancreatic beta-cell insulin secretion is the most common and most severe cause of persistent hypoglycemia in infants and children.
Diva D. De León +16 more
semanticscholar +1 more source
Frontiers in Pediatrics, 2021 Focal hyperinsulinism (HI) comprises nearly 50% of all surgically treated HI cases and is cured if the focal lesion can be completely resected. Pre-operative localization of the lesion is thus critical.
Elizabeth Rosenfeld +29 more
doaj +1 more source
Syndromic forms of congenital hyperinsulinism
Frontiers in Endocrinology, 2023 Congenital hyperinsulinism (CHI), also called hyperinsulinemic hypoglycemia (HH), is a very heterogeneous condition and represents the most common cause of severe and persistent hypoglycemia in infancy and childhood.
M. Zenker, K. Mohnike, Katja Palm
semanticscholar +1 more source
Frontiers in Endocrinology, 2023 Congenital hyperinsulinism (CHI) is a condition characterised by severe and recurrent hypoglycaemia in infants and young children caused by inappropriate insulin over-secretion.
M. G. Shaikh +35 more
semanticscholar +1 more source
Nature Genetics, 2022 Gene expression is tightly regulated, with many genes exhibiting cell-specific silencing when their protein product would disrupt normal cellular function1.
M. Wakeling +36 more
semanticscholar +1 more source