Results 21 to 30 of about 14,011 (206)
Congenital hyperinsulinism in a newborn presenting with poor feeding
SAGE Open Medical Case Reports, 2022 Hyperinsulinemic hypoglycemia is a condition linked to several genetic, metabolic, and growth disorders in which there is dysregulated insulin secretion.
Kiran Mazloom +4 more
doaj +1 more source
Brain injury due to persistent hyperinsulinemic hypoglycemia of infancy [PDF]
, 2007 A
De Visschere, Pieter +3 more
core +2 more sources
Orphanet Journal of Rare Diseases, 2021 Congenital hyperinsulinism (CHI), a major cause of persistent and recurrent hypoglycemia in infancy and childhood. Numerous pathogenic genes have been associated with 14 known genetic subtypes of CHI.
Wei Zhang, Yan-Mei Sang
doaj +1 more source
Expression and function of ATP-dependent potassium channels in zebrafish islet β-cells [PDF]
, 2017 ATP-sensitive potassium channels (K(ATP) channels) are critical nutrient sensors in many mammalian tissues. In the pancreas, K(ATP) channels are essential for coupling glucose metabolism to insulin secretion.
Conway, Hannah +8 more
core +2 more sources
Tissue Sodium Content and Arterial Hypertension in Obese Adolescents [PDF]
, 2019 Early-onset obesity is known to culminate in type 2 diabetes, arterial hypertension and subsequent cardiovascular disease. The role of sodium (Na+) homeostasis in this process is incompletely understood, yet correlations between Na+ accumulation and ...
Berger, Felix +12 more
core +3 more sources
Nifedipine in Congenital Hyperinsulinism - A Case Report. [PDF]
, 2016 PublishedJournal ArticleThis is the final version of the article. Available from Galenos Yayınevi via the DOI in this record.Congenital hyperinsulinism (CHI) is the commonest cause of persistent hypoglycemia in neonates.
Basak, D +4 more
core +1 more source
Laparoscopic Surgery for Focal-Form Congenital Hyperinsulinism Located in Pancreatic Head
Frontiers in Pediatrics, 2022 Background and AimsCongenital hyperinsulinism of infancy (CHI) is a rare condition that may cause irreversible severe neurological damage in infants. For children in whom medical management fails, partial or near-total pancreatectomy is then required ...
Zhe Wen +6 more
doaj +1 more source
PLoS ONE, 2020 There is a significant unmet need for a safe and effective therapy for the treatment of children with congenital hyperinsulinism. We hypothesized that amplification of the glucagon signaling pathway could ameliorate hyperinsulinism associated ...
Mangala M Soundarapandian +5 more
doaj +1 more source
Modern therapeutic aspects in two cases of congenital hyperinsulinism [PDF]
Romanian Journal of Pediatrics, 2020 In this article we will present the therapeutic and clinical aspects found in the case of two pediatric patients diagnosed with congenital hyperinsulinism.
Cristian Minulescu, Dana Spirea
doaj +1 more source
Medicina, 2014 Hyperinsulinism is the most common cause of hypoglycemia in infants. In many cases conservative treatment is not effective and surgical intervention is required. Differentiation between diffuse and focal forms and localization of focal lesions are the most important issues in preoperative management.
Indrė Petraitienė +6 more
openaire +3 more sources