Results 11 to 20 of about 6,192 (214)

Relative Hyperlactatemia in the Emergency Department [PDF]

Frontiers in Medicine, 2020
Objective: The clinical interpretation of lactate ≤ 2.00 mmol/L in emergency department (ED) patients is not well-characterized. This study aims to determine the optimal cutoff value for lactate within the reference range that predicts in-hospital mortality among ED patients.
Ralphe Bou Chebl, Sarah Jamali, Nancy Mikati, Reem Al Assaad, Karim Abdel Daem, Nadim Kattouf, Rawan Safa, Maha Makki, Hani Tamim, Gilbert Abou Dagher   +9 more
openaire   +5 more sources

Hyperlactatemia and Cardiac Surgery

The Journal of ExtraCorporeal Technology, 2017
The normal blood lactate level is 0–2 mmol/L, and a value above 3–5 mmol/L is variably used to define hyperlactatemia. In cardiac surgical patients, hyperlactatemia can arise from both hypoxic and non-hypoxic mechanisms. The major non-hypoxic mechanism is likely stress-induced accelerated aerobic metabolism, in which elevated lactate results from a ...
Jonathon, Minton, David A, Sidebotham
openaire   +3 more sources

Sepsis-associated hyperlactatemia [PDF]

Critical Care, 2014
AbstractThere is overwhelming evidence that sepsis and septic shock are associated with hyperlactatemia (sepsis-associated hyperlactatemia (SAHL)). SAHL is a strong independent predictor of mortality and its presence and progression are widely appreciated by clinicians to define a very high-risk population.
Garcia-Alvarez, M, Marik, P, Bellomo, R
core   +8 more sources

Persistent Sepsis-Induced Hypotension without Hyperlactatemia: A Distinct Clinical and Physiological Profile within the Spectrum of Septic Shock [PDF]

Critical Care Research and Practice, 2012
Introduction. A subgroup of septic shock patients will never develop hyperlactatemia despite being subjected to a massive circulatory stress. Maintenance of normal lactate levels during septic shock is of great clinical and physiological interest.
Glenn Hernandez, Alejandro Bruhn, Ricardo Castro, Cesar Pedreros, Maximiliano Rovegno, Eduardo Kattan, Enrique Veas, Andrea Fuentealba, Tomas Regueira, Carolina Ruiz, Can Ince   +10 more
doaj   +3 more sources

Hyperlactatemia associated with elective tumor craniotomy: Protocol for an observational study of pathophysiology and clinical implications.

PLoS ONE, 2022
Hyperlactatemia occurs frequently after brain tumor surgery. Existing studies are scarce and predominantly retrospective, reporting inconsistent associations to new neurological deficits and prolonged hospital stay.
Alexandra Vassilieva, Kirsten Møller, Jane Skjøth-Rasmussen, Martin Kryspin Sørensen   +3 more
doaj   +2 more sources

Hyperlactatemia syndromes in people with HIV infection

Current Opinion in Infectious Diseases, 2002
Hyperlactatemia associated with use of nucleoside analogue reverse transcriptase inhibitors (NRTIs) is not a single entity but a spectrum of abnormalities. The spectrum reflects varying degrees of derangement in systemic homeostasis in the face of primary drug effects on lactate load.
John, M., Mallal, S.
openaire   +3 more sources

Perioperative Outcomes of Hyperlactatemia during Craniotomy: A Systematic Review and Meta-Analysis of 1,832 Patients

Journal of Neuroanaesthesiology and Critical Care, 2023
Background Hyperlactatemia, is common in patients undergoing neurosurgical procedures. Several studies have identified potential risk factors for developing hyperlactatemia in neurosurgical patients, including body mass index, surgery duration,
Mahfouz M. Sharapi, Nada M. Al-dardery, Mohamed A. El-Samahy, Amany E. Mahfouz, Ahmed S. Aljabali, Hazem S. Ghaith   +5 more
doaj   +2 more sources

Lactic acidosis, hyperlactatemia and sepsis

Italian Journal of Medicine, 2016
Among hospitalized patients, lactic acidosis represents the most common cause of metabolic acidosis. Lactate is not just a metabolic product of anaerobic glycolysis but is triggered by a variety of metabolites even before the onset of anaerobic metabolism as part of an adaptive response to a hypermetabolic state.
Andrea Montagnani, Roberto Nardi
openaire   +4 more sources

Severe Lactic Acidosis in Decompensated Cirrhosis Despite Nondiagnostic Imaging. [PDF]

Clin Case Rep
ABSTRACT Lactic acidosis is a strong predictor of mortality in cirrhosis, reflecting both impaired hepatic clearance and systemic tissue hypoxia. We describe a 38‐year‐old man with decompensated alcohol‐associated cirrhosis who developed severe lactic acidosis despite stable hemodynamics and initially nondiagnostic vascular imaging.
Ganju N, Nwachukwu CV, Santiago-Gonzalez J, Naeem S, Azinge N, Laiyemo AO.   +5 more
europepmc   +2 more sources

Hyperlactatemia in diabetic ketoacidosis

Diabetic Medicine, 2021
AbstractAimsThe study examined the prevalence and degree of lactate elevation in diabetic ketoacidosis, and explored which biochemical abnormalities predicted L‐lactate levels.MethodsWe reviewed episodes of diabetic ketoacidosis from 79 diabetes patients (one episode per patient).
Umesh Masharani, Lisa A. Strycker, Ann A. Lazar, Karin Wu, George A. Brooks   +4 more
openaire   +4 more sources