Results 41 to 50 of about 6,192 (214)

Hyperlactatemia in critically ill children: The clinical value of lactate for predicting mortality in the pediatric intensive care unit

Journal of Pediatric Critical Care, 2018
Objective: To determine the prevalence of hyperlactatemia among critically ill children and to evaluate the clinical value of lactate levels measured at admission to the pediatric intensive care unit (PICU) to predict mortality. Methods: This prospective
Bijay Kumar Meher, Devadarshini Sahoo, Deepti Damayanty Pradhan, Saroj Kumar Satpathy, Alok Satyaprakash Nayak   +4 more
doaj   +1 more source

Acidosis predicts mortality independently from hyperlactatemia in patients with sepsis

, 2020
RATIONALE AND OBJECTIVES Acidosis and hyperlactatemia predict outcome in critically ill patients. We assessed BE and pH for risk prediction capabilities in a sub-group of septic patients in the MIMIC-III database.
Lichtenauer, M., Heramvand, N., Hoppe, Uta C, Masyuk, Maryna, Kelm, Malte, Wernly, B, Bakker, Jan, Heramvand, N, Kelm, M, Niederseer, David, Rezar, Richard, Rezar, R., Rezar, R, Bruno, Raphael Romano, Bakker, Hanneke, Lichtenauer, Michael, Masyuk, M, Jung, C, Kelm, M., Wernly, Bernhard, Bakker, J, Bruno, R. R., Niederseer, D., Wernly, B., Jung, C., Niederseer, D, Jung, Christian, Bakker, Jan; id_orcid, Bruno, RR, Heramvand, Nadia, Masyuk, M., Hoppe, U. C., Lichtenauer, M, Hoppe, UC   +33 more
core   +1 more source

Hyperlactatemia in patients undergoing adult cardiac surgery under cardiopulmonary bypass: Causative factors and its effect on surgical outcome

Annals of Cardiac Anaesthesia, 2016
Objectives of the Study: To identify the factors causing high lactate levels in patients undergoing cardiac surgery under cardiopulmonary bypass (CPB) and to assess the association between high blood lactate levels and postoperative morbidity and ...
Rakesh Naik, Gladdy George, Sathappan Karuppiah, Madhu Andrew Philip   +3 more
doaj   +1 more source

The risk of venous thromboembolism and blood hyperlactatemia is associated with increased mortality among critically ill patients with Covid‐19

The Clinical Respiratory Journal, 2023
Introduction Coronavirus disease 2019 (Covid‐19) following venous thromboembolism (VTE) and blood hyperlactatemia are associated with higher mortality. However, reliable biomarkers for this association remain to be elucidated. This study investigated the
Amal F. Alshammary, Hassan M. AlQarni, Raed Farzan, Imran Ali Khan, Vishal Vennu   +4 more
doaj   +1 more source

Lactate: The Fallacy of Oversimplification

Biomedicines, 2023
Almost a quarter of a millennium after the discovery of an acidic substance in sour milk by Swedish chemist Carl Wilhelm Scheele and more than 100 years after the demonstration of a tight connection between this lactic acid and tissue hypoxia in shock ...
Jiri Müller, Jaroslav Radej, Jan Horak, Thomas Karvunidis, Lenka Valesova, Miroslav Kriz, Martin Matejovic   +6 more
doaj   +1 more source

Duration of postoperative hyperlactatemia has predictive value in recurrent fistula after major definitive surgery for intestinal fistula

BMC Surgery, 2022
Purpose The present study aimed to identify the predictive value of duration of postoperative hyperlactatemia in screening patients at high risk of recurrent fistula after major definitive surgery (DS) for intestinal fistula.
Ming Huang, Weiliang Tian, Shikun Luo, Xi Xu, Zheng Yao, Risheng Zhao, Qian Huang   +6 more
doaj   +1 more source

Risk Factors for Mortality in Neonatal Gastric Perforation: A Retrospective Cohort Study

Frontiers in Pediatrics, 2021
Background: Neonatal gastric perforation is a rare but life-threatening issue. The aim of this study was to describe the clinical characteristics and prognosis of patients with neonatal gastric perforation and identify predictive factors for poor ...
Yao Huang, Qi Lu, Nan Peng, Li Wang, Yan Song, Qin Zhong, Peng Yuan   +6 more
doaj   +1 more source

Clinical outcome in presence of no hyperlactatemia, moderate or severe hyperlactatemia.

, 2015
Data are number (%).HL: hyperlactatemiaClinical outcome in presence of no hyperlactatemia, moderate or severe hyperlactatemia.
Paolo Bianchi (17641), Tommaso Aloisio (740837), Giovanni Carboni (740834), Marco Ranucci (360634), Mauro Cotza (740835), Umberto Di Dedda (740836)   +5 more
core   +1 more source

Exploring dynamic change in arterial base excess with patient outcome and lactate clearance in the intensive care unit by hierarchical time-series clustering

Frontiers in Medicine, 2022
BackgroundHyperlactatemia is common in the intensive care unit (ICU) and relevant to prognosis, while the process of lactate normalization requires a relatively long period.
Dongkai Li, Shengjun Liu, Jiahui Zhang, Wei Cheng, Jiayu Mao, Na Cui   +5 more
doaj   +1 more source

Expanding the Phenotype of TUFM‐Related Combined Oxidative Phosphorylation Deficiency 4

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Combined oxidative phosphorylation deficiency 4 (COXPD4) is a rare mitochondrial condition caused by biallelic deleterious variants in the nuclear‐encoded gene TUFM. To date, most individuals with COXPD4 have presented with encephalopathy, hypotonia, and abnormal brain imaging. Many of the reported individuals died in infancy. We aim to expand
Noémie Villeneuve‐Cloutier, Jodi Warman‐Chardon, Danielle K. Bourque   +2 more
wiley   +1 more source