Results 71 to 80 of about 6,192 (214)

Novel Compound Heterozygous Variants in the COG5 Gene Causing Fetal Hydrops and Skeletal Dysplasia

Molecular Genetics &Genomic Medicine, Volume 14, Issue 4, April 2026.
Two affected fetuses in a COG5‐CDG family exhibited fetal hydrops and skeletal malformations, which were found to segregate with the paternal frameshift variant c.1972del and the maternal splice‐site variant c.2168_2168+4delinsCATAAAA in the COG5 gene.
Qi Yang, Wei He, Qiang Zhang, Sheng Yi, Xunzhao Zhou, Linlin Wang, Shang Yi, Zailong Qin, Jingsi Luo   +8 more
wiley   +1 more source

Lactate-Protected Hypoglycemia (LPH)

Frontiers in Neuroscience, 2020
Here, we provide an overview of the concept of a lactate-protected hypoglycemia (“LPH”), originally proposed as lowering glucose while simultaneously increasing lactate concentration as a method by which tumors might be targeted.
Matthew L. Goodwin, L. Bruce Gladden, Maarten W. N. Nijsten   +2 more
doaj   +1 more source

Hyperlactatemia in critical illness and cardiac surgery [PDF]

Critical Care, 2010
We read with interest the article by Nichol and colleagues [1] in a recent issue of Critical Care. Their study of more than 7,000 medical and surgical patients supports the claim that an admission plasma lactate level in the upper normal range is associated with increased mortality.
O'Connor, Edna D., Fraser, John F.
openaire   +4 more sources

Bridging Critically Ill Patients With Cirrhosis to Transplant With Renal Replacement Therapy: A Multicenter Cohort Study

Liver International, Volume 46, Issue 4, April 2026.
ABSTRACT Background & Aims The efficacy of renal replacement therapy (RRT) in critically ill patients with cirrhosis remains dubious. We aimed to assess the impact of RRT on these patients' outcomes. Methods Multicenter retrospective cohort study including adult patients with cirrhosis admitted to intensive care units at University of Alberta Hospital (
Filipe S. Cardoso, Minjee Kim, Beverley Kok, Richard Wunderink, Juan G. Abraldes, Constantine J. Karvellas   +5 more
wiley   +1 more source

The Association Between Nutritional Status and Clinical Outcomes of COVID‐19 Patients in Intensive Care Unit in Vietnam: A Retrospective Study

Health Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Aims This study aimed to assess the nutritional status of COVID‐19 patients within the first 24 h of Intensive Care Unit (ICU) admission and to determine its association with the risk of mechanical ventilation and mortality. Methods This retrospective study analyzed electronic medical records from 342 COVID‐19 patients admitted to Hanoi ...
Hoai Thu Thi Nguyen, Yen Ngoc Ma, Linh Thuy Nguyen, Ngoc Lan Thi Nguyen, Thuy Thi Le, Lan Thi Phuong Dam, Tuan Duc Nguyen   +6 more
wiley   +1 more source

Retrospective Evaluation of the Prognostic Utility of Clinical and Laboratory Findings in Hospitalized Cats with Pancreatitis

Animals
Pancreatitis in cats ranges from mild forms with low mortality to severe cases with poor prognosis, and early identification of high-risk patients remains a challenge.
Yada Siriphanporn, Anuwat Wiratsudakul, Suwicha Kasemsuwan, Piyathip Chuchalermporn, Monchanok Vijarnsorn, Narudee Kashemsant   +5 more
doaj   +1 more source

Untargeted Proteomics Profiling of Liver and Plasma in Fed and Fasted Liver‐Specific Glycogen Storage Disease Type Ia (GSD Ia) Mice: Toward Potential Protein Biomarkers

Journal of Inherited Metabolic Disease, Volume 49, Issue 2, March 2026.
ABSTRACT Glycogen storage disease type Ia (GSD Ia) is a rare autosomal recessive inherited disorder of carbohydrate metabolism, caused by a deficiency in glucose 6‐phosphatase‐α (G6PC1). Patients primarily suffer from failure to thrive, hepatomegaly, and severe fasting intolerance, biochemically characterized by hypoketotic, hypoglycemia, and ...
Ruiqi Xiao, Hilda I. de Vries, Candelas Gross‐Valle, Aycha Bleeker, Terry G. J. Derks, Barbara M. Bakker, Maaike H. Oosterveer, Justina C. Wolters   +7 more
wiley   +1 more source

A Rapid Increase in Serum Lactate Levels after Cardiovascular Surgery Is Associated with Postoperative Serious Adverse Events: A Single Center Retrospective Study

Diagnostics
Background/Objectives: Hyperlactatemia is a common predictive factor for poor post-cardiovascular surgery outcomes. However, it is not well understood whether the rapid postoperative lactate level elevation in a short period of time is associated with ...
Kenichiro Kikuchi, Satoshi Kazuma, Yoshiki Masuda   +2 more
doaj   +1 more source

Evaluation of the Use of a Medium Cut‐Off Dialyser Theranova 400 for Severe Metaldehyde Intoxication in Three Dogs: Dialytic Clearance and Therapeutic Response

Veterinary Medicine and Science, Volume 12, Issue 2, March 2026.
Three dogs with severe neurological signs from acute metaldehyde intoxication were treated with emergent haemodialysis using a medium cut‐off (MCO) dialyser. Neurological signs resolved within a single 4‐h session without adverse effects. Dialytic clearance of metaldehyde was 12.5 times higher than intrinsic clearance, demonstrating the clinical ...
Maxime Rodary, Claudia Iannucci, Andreas F. Lehner, Birgit Puschner, John P. Buchweitz, Alessio Vigani   +5 more
wiley   +1 more source

raw data for "Clinical impact of intraoperative hyperlactatemia during craniotomy"

, 2019
raw data for tables 1-4 and figure 1 in PONE-D-19-23758 PLOS ONE article "Clinical impact of intraoperative hyperlactatemia during ...
Diana Romano (7474154)
core   +1 more source