Results 11 to 20 of about 7,125 (253)

Hyperleukocytosis: pseudohyperkalaemia and other biochemical abnormalities in hyperleukocytosis [PDF]

Clinical Chemistry and Laboratory Medicine, 2009
Robert Bird
exaly   +6 more sources

Hyperleukocytosis in Pediatric Patients with Acute Lymphoblastic Leukemia: Demographic and Clinical Characteristics

Journal of Clinical Medicine
Background: Hyperleukocytosis, defined as a total leukocyte count of more than 50,000/mm3 leukocytes, occurs in almost one in five children with acute lymphoblastic leukemia (ALL). It represents an unfavorable prognostic factor in this disease.
Małgorzata Mitura-Lesiuk, Maciej Dubaj
exaly   +2 more sources

Hyperleukocytosis and Thrombocytosis

Journal of Pediatric Critical Care
Hyperleukocytosis and thrombocytosis represent critical hematological emergencies frequently encountered in pediatric intensive care units. Hyperleukocytosis, defined as a white blood cell count exceeding 100,000/μL, occurs predominantly in acute ...
S. Vasanth Kumar
doaj   +2 more sources

Practice variability in the management of critical pertussis: a multicenter survey of pediatric intensivists in the Arabian Gulf Cooperation Council region [PDF]

Frontiers in Pediatrics
BackgroundCritical pertussis continues to cause significant morbidity and mortality in infants necessitating pediatric intensive care. Despite advances in supportive care, knowledge gaps persist.
Mohammad Alghounaim, Mohamad-Hani Temsah, Mohamad-Hani Temsah, Abdulrahman Aldaithan, Abdulrahman Aldaithan, Manu S. Sundaram, Manu S. Sundaram, Amal Al Daylami, Musaab Ramsi, Saif Awlad Thani, Yasser Kazzaz, Yasser Kazzaz, Yasser Kazzaz, Abdulla Alfraij   +13 more
doaj   +2 more sources

Interference in HbA1c measurement: a case of electropherogram shift due to hyperleukocytosis leading to the discovery of leukemic mantle cell lymphoma [PDF]

Scandinavian Journal of Clinical and Laboratory Investigation
HbA1c is a pivotal biomarker in diabetes management, reflecting long-term glycaemic control. HbA1c is often measured with capillary electrophoresis, which generally is a very precise technique, but there can be interference, especially in the case of ...
Gade, Inger Lise, Hviid, Claus V. B., Strandberg, Jesper   +2 more
core   +3 more sources

Hyperleukocytosis, leukemoid reaction caused by malignant peritoneal mesothelioma: a case report and review of literature [PDF]

Frontiers in Oncology
Paraneoplastic leukemoid reaction (PLR)-induced hyperleukocytosis remains a critical diagnostic challenge. Malignant peritoneal mesothelioma, known for its nonspecific clinical presentation, often evades early detection. We report a 75-year-old male with
Kaibo Zhu, Dan Zhou, Kang Liu, Lingzhen Wu, Lingzhen Wu, Juan Jin, Zimian Luo   +6 more
doaj   +2 more sources

Leukoreductive response to the combination of sorafenib and chemotherapy in hyperleukocytosis of FLT3-ITD mutated pediatric AML

Frontiers in Pediatrics, 2022
Twelve to 22% of pediatric acute myeloid leukemia (AML) patients present with hyperleukocytosis, which is one of the main risk factors of early death due to its clinical complications: leukostasis, causing pulmonary or central nervous system injuries ...
Franziska Schmidt, Miriam Erlacher, Charlotte Niemeyer, Dirk Reinhardt, Jan-Henning Klusmann   +4 more
doaj   +2 more sources

Twenty Years of Therapeutic Leukocytapheresis in Newly Diagnosed Acute Myeloid Leukemia: Insights From A Single Center. [PDF]

J Clin Apher
ABSTRACT Acute myeloid leukemia (AML) is a heterogeneous hematologic malignancy, and 5%–20% of newly diagnosed patients present with hyperleukocytosis (HL). HL, most often defined as WBC > 100 000/μL, is a hematologic emergency associated with severe complications, early mortality, and poor prognosis, requiring immediate intervention.
Latal V, Skoumalova I, Palova M, Szotkowski T, Cernan M, Navratilova J, Urbankova H, Pikalova Z, Raida L, Faber E, Papajik T.   +10 more
europepmc   +2 more sources

An Infant With Hyper IgE Syndrome Mimicking Acute Leukemia. [PDF]

Clin Case Rep
ABSTRACT Although infection, inflammation, and leukemia are major causes of leukocytosis, hyper IgE syndrome should be considered if eosinophilia is present. Hyper IgE syndrome may mimic acute leukemia when complicated by severe infection.
Matsui Y, Uemura S, Kishimoto K, Hamada K, Morisada N, Hasegawa D, Kosaka Y.   +6 more
europepmc   +2 more sources

Rapid Transformation to Myeloid Blast Crisis in a Pediatric CML Patient Harboring a Complex t(7;9;22)(q11.23;q34;q11.2) Variant Translocation: A Case Report. [PDF]

EJHaem
ABSTRACT Chronic myeloid leukemia (CML) in chronic phase (CP) typically follows an indolent course. We report a highly aggressive pediatric case with a discordant presentation. A 10‐year‐old girl presented with rapidly progressive symptoms and hyperleukocytosis (WBC 448.7 × 109/L).
Haidary AM, Noor S, Hussaini N, Amarkhail A, Ahmad M, Muhib I, Esmat E, Malakzai HA, Hakimi A, Haidari M, Ibrahimkhil AS, Saadaat R.   +11 more
europepmc   +2 more sources