Results 21 to 30 of about 7,125 (253)

Hyperleukocytosis (Re)Visited- Is it always Leukaemia: A Report of Two Cases and Review of Literature [PDF]

Journal of Clinical and Diagnostic Research, 2020
Hyperleukocytosis is defined as total leukocyte count of more than 100×109 /L. Commonly seen in leukaemic conditions, nonleukaemic causes are usually not encountered and thought of. We report two such non-malignant cases of hyperleukocytosis.
Ashutosh Rath, Richa Gupta
doaj   +1 more source

Initial Hyperleukocytosis and Neutrophilia in Nasopharyngeal Carcinoma: Incidence and Prognostic Impact. [PDF]

PLoS ONE, 2015
BACKGROUND:This study aimed to evaluate initial hyperleukocytosis and neutrophilia as prognostic indicators in patients with nasopharyngeal carcinoma. METHODS:A retrospective analysis of 5,854 patients identified from a cohort of 6,035 patients diagnosed
Zhen Su, Yan-Ping Mao, Pu-Yun OuYang, Jie Tang, Fang-Yun Xie   +4 more
doaj   +1 more source

Hypercapnia as a Key Mechanism in the Development of Pulmonary Hypertension in Malignant Pertussis: A Case Report. [PDF]

Respirol Case Rep
Despite intensive care advances, malignant pertussis (MP) remains highly lethal. Our case suggests that hypercapnia‐induced pulmonary vasoconstriction may play a reversible role in MP pathophysiology. Thus, targeting hypercapnia control could represent a promising therapeutic approach in managing this severe complication.
Muñoz-Bonet JI, Sebastián-Cuevas FJ, Flor-Macián EM, Ortega-Sánchez MDC, Rodríguez-Sacristán A, Brines J.   +5 more
europepmc   +2 more sources

A Case of Hyperkalemia Versus Pseudohyperkalemia in Chronic Lymphocytic Leukemia [PDF]

, 2020
Introduction: Both hyperkalemia and pseudohyperkalemia occur in the emergency department. True hyperkalemia necessitates emergent treatment while pseudohyperkalemia requires recognition to prevent inappropriate treatment.
Geary, Sean P., Le, Rachel D.
core   +1 more source

Ten-Year Outcome of a Patient With Concurrent Pelvic Myeloid Sarcoma and Underlying Chronic Myeloid Leukaemia in Chronic Phase: A Case Report and Literature Review. [PDF]

Cancer Rep (Hoboken)
ABSTRACT Background Myeloid sarcoma is a rare solid tumour of immature myeloid precursors occurring in an extramedullary site. It often presents significant diagnostic and therapeutic challenges to clinical haematologists. Case We describe a previously healthy patient who presented simultaneously with hyperleucocytic chronic myeloid leukaemia in ...
Yong KY, Lim SH, Lau LG, Chew LP.
europepmc   +2 more sources

Leukopheresis for profound hyperleukocytosis [PDF]

Transfusion and Apheresis Science, 2012
Leukocytoreduction by leukopheresis is recommended for hyperleukocytosis with leukemia, especially when accompanied by neurologic or respiratory symptoms. A single 1-1.5 blood volume leukocytopheresis is expected to reduce the leukocyte count by 30-60%.A 35 year old man presented with a 2 month history of hearing and visual loss and was found to have ...
Seble S, Chekol, Bhavana, Bhatnagar, Ivana, Gojo, John R, Hess   +3 more
openaire   +2 more sources

Challenging management of severe differentiation syndrome in pediatric acute promyelocytic leukemia treated with ATRA/ATO

Mediterranean Journal of Hematology and Infectious Diseases, 2022
The ATRA/ATO combination treatment of acute promyelocytic leukemia (APL) represents a paradigm of successful targeted and chemotherapy-free treatment in oncology.
Alessandro Molinaro, Daniela Zanta, Maria Luisa Moleti, Fiorina Giona, Valentino Conter, Carmelo Rizzari, Andrea Biondi, Anna Maria Testi   +7 more
doaj   +1 more source

Benefits of dexamethasone on early outcomes in patients with acute myeloid leukemia with hyperleukocytosis: a propensity score matched analysis

Annals of Hematology, 2023
Hyperleukocytosis is associated with a significant early mortality rate in patients with acute myeloid leukemia (AML). To date, no controlled trial has ever evaluated a strategy to reduce this risk, and the initial management of these patients remains ...
M. Cerrano, S. Chevret, E. Raffoux, Florence Rabian, M. Sébert, S. Valade, R. Itzykson, V. Lemiale, L. Adès, N. Boissel, H. Dombret, É. Azoulay, E. Lengliné   +12 more
semanticscholar   +1 more source

Minimally early morbidity in children with acute myeloid leukemia and hyperleukocytosis treated with prompt chemotherapy without leukapheresis

Journal of the Formosan Medical Association, 2014
Patients with acute myeloid leukemia (AML) and hyperleukocytosis, defined as an initial white blood cell (WBC) count of ≥ 100 × 109/L, are often treated with leukapheresis.
Kuan-Hao Chen, Hsi-Che Liu, Der-Cherng Liang, Jen-Yin Hou, Ting-Huan Huang, Ching-Yi Chang, Ting-Chi Yeh   +6 more
doaj   +1 more source

Long term impact of hyperleukocytosis in newly diagnosed acute myeloid leukemia patients undergoing allogeneic stem cell transplantation : An analysis from the acute leukemia working party of the EBMT [PDF]

, 2017
Up to 20% of acute myeloid leukemia (AML) patients present initially with hyperleukocytosis, placing them at increased risk for early mortality during induction. Yet, it is unknown whether hyperleukocytosis still retains prognostic value for AML patients
Blaise, Didier, Bourhis, Jean H., Canaani, Jonathan, Chevallier, Patrice, Cornelissen, Jan, Deconinck, Eric, Forcade, Edouard, Gedde-Dahl, Tobias, Huynh, Anne, Labopin, Myriam, Mohty, Mohamad, Nagler, Arnon, Nihtinen, Anne, Socie, Gerard   +13 more
core   +1 more source