Results 1 to 10 of about 666,379 (164)

Ghrelin Levels in Male Patients with Hyperlipoproteinemia I, II versus Type 2 Diabetes Mellitus.

مجلة كلية الطب, 2014
Background; Hyperlipoproteinemia (HLP)  are divided in primary and secondary subtypes. Primary HLP is usually due to genetic causes. Secondary HLP is resulting from another underlying disorder such as diabetes mellitus that leads to alterations in plasma
Salma A. Abbas, Samir L. Shkhaier, Baydaa A. Abed   +2 more
doaj   +4 more sources

Identification of an apoC-II variant (apoC-IIBethesda) in a kindred with apoC-II deficiency and type I hyperlipoproteinemia.

Journal of Lipid Research, 1988
Apolipoprotein (apo) C-II deficiency is characterized by elevated plasma triglycerides, chylomicrons, and very low density lipoproteins, as well as reduced levels of low density and high density lipoproteins.
D L Sprecher, L Taam, R E Gregg, S S Fojo, D M Wilson, M L Kashyap, H B Brewer, Jr   +6 more
doaj   +2 more sources

Control of sterol synthesis and of hydroxymethylglutaryl CoA reductase in skin fibroblasts grown from patients with homozygous type II hyperlipoproteinemia

Journal of Lipid Research, 1975
In skin fibroblasts grown from four children with a homozygous form of type II hyperlipoproteinemia, the feedback control of sterol synthesis and the inhibitory effect on hydroxymethylglutaryl (HMG) CoA reductase activity by serum or low density ...
J. Avigan, S.J. Bhathena, M.E. Schreiner
doaj   +2 more sources

Isolation and characterization of an apoA-II-containing lipoprotein (LP-A-II:B complex) from plasma very low density lipoproteins of patients with Tangier disease and type V hyperlipoproteinemia.

Journal of Lipid Research, 1991
Previous studies have shown that very low density lipoproteins (VLDL) from patients with Tangier disease are less effective as a substrate for human milk lipoprotein lipase (LPL) than VLDL from normal controls as assessed by measuring the first order ...
P Alaupovic, C Knight-Gibson, CS Wang, D Downs, E Koren, HB Brewer, Jr, RE Gregg   +6 more
doaj   +2 more sources

2022 Consensus statement on the management of familial hypercholesterolemia in Korea [PDF]

The Korean Journal of Internal Medicine, 2022
Familial hypercholesterolemia (FH) is the most common monogenic disorder. Due to the marked elevation of cardiovascular risk, the early detection, diagnosis, and proper management of this disorder are critical.
Chan Joo Lee, Minjae Yoon, Hyun-Jae Kang, Byung Jin Kim, Sung Hee Choi, In-Kyung Jeong, Sang-Hak Lee   +6 more
doaj   +1 more source

Role of PCSK9 Inhibitors in Patients with Familial Hypercholesterolemia [PDF]

Endocrinology and Metabolism, 2021
Patients with familial hypercholesterolemia (FH) are at high or very high risk for cardiovascular disease. Those with heterozygous FH (HeFH) often do not reach low-density lipoprotein cholesterol (LDL-C) targets with statin and ezetimibe therapy, and ...
Brian Tomlinson, Nivritti Gajanan Patil, Manson Fok, Christopher Wai Kei Lam   +3 more
doaj   +1 more source

Familial hypercholesterolemia within cardiology practice – single-center experience during 2-year period

Research in Cardiovascular Medicine, 2022
Background: Familial hypercholesterolemia (FH) is an inherited disorder characterized by significantly elevated levels of low-density lipoprotein (LDL) cholesterol and is usually diagnosed after the occurrence of major adverse cardiovascular event.
Edin Begic, Ada Djozic, Emina Karavelic, Nadira Zatric, Adela Sinancevic, Alen Dzubur, Azra Durak-Nalbantic, Alden Begic, Nedim Begic, Amina Sahbaz, Esma Hasanagic, Ena Gogic, Nabil Naser, Fuad Zukic, Edin Medjedovic, Amer Iglica, Mirela Halilcevic, Zijo Begic   +17 more
doaj   +1 more source

Molecular diagnosis methods in familial hypercholesterolemia

Anatolian Journal of Cardiology, 2020
Familial hypercholesterolemia (FH) is considered the genetic cause of coronary heart disease and ischemic stroke. FH is mainly an autosomal codominant pattern-based disorder and is primarily determined by point mutations within the low-density ...
Valeriu Moldovan, Claudia Banescu, Minodora Dobreanu   +2 more
doaj   +1 more source

Interaction between Glucose and Lipid Metabolism: More than Diabetic Dyslipidemia [PDF]

Diabetes & Metabolism Journal, 2015
Glucose and lipid metabolism are linked to each other in many ways. The most important clinical manifestation of this interaction is diabetic dyslipidemia, characterized by elevated triglycerides, low high density lipoprotein cholesterol (HDL-C), and ...
Klaus G. Parhofer
doaj   +1 more source

A case report of palmar xanthoma with xanthomatous neuropathy

SAGE Open Medical Case Reports, 2021
Xanthomas are plaques or nodules consisting of an accumulation of excess lipids, resulting in the formation of foam cells in the skin or tendons. Typically, xanthomas are not accompanied by other symptoms. Here, we report a patient with a presentation of
Hyun Yi Lee, Dae Won Koo, Joong Sun Lee
doaj   +1 more source