Results 11 to 20 of about 5,561 (244)

Alternative cascade-testing protocols for identifying and managing patients with familial hypercholesterolaemia: systematic reviews, qualitative study and cost-effectiveness analysis

Health Technology Assessment, 2023
Background Cascade testing the relatives of people with familial hypercholesterolaemia is an efficient approach to identifying familial hypercholesterolaemia.
Nadeem Qureshi, Bethan Woods, Rita Neves de Faria, Pedro Saramago Goncalves, Edward Cox, Jo Leonardi-Bee, Laura Condon, Stephen Weng, Ralph K Akyea, Barbara Iyen, Paul Roderick, Steve E Humphries, William Rowlands, Melanie Watson, Kate Haralambos, Ryan Kenny, Dev Datta, Zosia Miedzybrodzka, Christopher Byrne, Joe Kai   +19 more
doaj   +2 more sources

Premature development of iliac artery stenosis in asymptomatic type II hyperlipoproteinemia. [PDF]

Arteriosclerosis: An Official Journal of the American Heart Association, Inc., 1984
There is conflicting evidence on the relationship between increased low density lipoprotein (LDL) concentration in Type II hyperlipoproteinemia and premature development of peripheral atherosclerosis of the lower limbs. We evaluated the early signs of iliac artery involvement in patients with asymptomatic Type II hyperlipoproteinemia. Of these, 23 were
Paolo Rubba, A. Postiglione, Barbieri Simone, F. Faccenda, Gabriele Riccardi, Mario Mancini   +5 more
openalex   +5 more sources

Coronary Artery Bypass Grafting on Microaxial Flow Pump Support in Patients With Severely Reduced Left Ventricular Ejection Fraction. [PDF]

Artif Organs
Coronary artery revascularization with microaxial flow pump support in patients with severely reduced left ventricular ejection fraction is an emerging technique in cardiac surgery. In this manuscript, we present early results, highlight the advantages, and discuss the key limitations of this approach.
Nersesian G, Lewin D, Hrytsyna Y, Lanmueller P, Ott S, Merke N, Falk V, Schoenrath F, Potapov E, Abd El Al A.   +9 more
europepmc   +2 more sources

2022 Consensus statement on the management of familial hypercholesterolemia in Korea [PDF]

The Korean Journal of Internal Medicine, 2022
Familial hypercholesterolemia (FH) is the most common monogenic disorder. Due to the marked elevation of cardiovascular risk, the early detection, diagnosis, and proper management of this disorder are critical.
Chan Joo Lee, Minjae Yoon, Hyun-Jae Kang, Byung Jin Kim, Sung Hee Choi, In-Kyung Jeong, Sang-Hak Lee   +6 more
doaj   +1 more source

Role of PCSK9 Inhibitors in Patients with Familial Hypercholesterolemia [PDF]

Endocrinology and Metabolism, 2021
Patients with familial hypercholesterolemia (FH) are at high or very high risk for cardiovascular disease. Those with heterozygous FH (HeFH) often do not reach low-density lipoprotein cholesterol (LDL-C) targets with statin and ezetimibe therapy, and ...
Brian Tomlinson, Nivritti Gajanan Patil, Manson Fok, Christopher Wai Kei Lam   +3 more
doaj   +1 more source

Familial hypercholesterolemia within cardiology practice – single-center experience during 2-year period

Research in Cardiovascular Medicine, 2022
Background: Familial hypercholesterolemia (FH) is an inherited disorder characterized by significantly elevated levels of low-density lipoprotein (LDL) cholesterol and is usually diagnosed after the occurrence of major adverse cardiovascular event.
Edin Begic, Ada Djozic, Emina Karavelic, Nadira Zatric, Adela Sinancevic, Alen Dzubur, Azra Durak-Nalbantic, Alden Begic, Nedim Begic, Amina Sahbaz, Esma Hasanagic, Ena Gogic, Nabil Naser, Fuad Zukic, Edin Medjedovic, Amer Iglica, Mirela Halilcevic, Zijo Begic   +17 more
doaj   +1 more source

Molecular diagnosis methods in familial hypercholesterolemia

Anatolian Journal of Cardiology, 2020
Familial hypercholesterolemia (FH) is considered the genetic cause of coronary heart disease and ischemic stroke. FH is mainly an autosomal codominant pattern-based disorder and is primarily determined by point mutations within the low-density ...
Valeriu Moldovan, Claudia Banescu, Minodora Dobreanu   +2 more
doaj   +1 more source

Expression of type III hyperlipoproteinemia in apolipoprotein E2 (Arg158 --> Cys) homozygotes is associated with hyperinsulinemia [PDF]

, 2002
Type III hyperlipoproteinemia (HLP) is mainly found in homozygous carriers of apolipoprotein E2 (apoE2, Arg158-->Cys). Only a small percentage (< 5%) of these apoE2 homozygotes develops hyperlipidemia, indicating that additional environmental and genetic
Beer, F. (Femke) de, Duijn, C.M. (Cornelia) van, Gevers Leuven, J.A., Havekes, L.M., Hoogerbrugge, N. (Nicoline), Kastelein, J.J.P. (John), Smelt, A.H., Stalenhoef, A.F.   +7 more
core   +8 more sources

Interaction between Glucose and Lipid Metabolism: More than Diabetic Dyslipidemia [PDF]

Diabetes & Metabolism Journal, 2015
Glucose and lipid metabolism are linked to each other in many ways. The most important clinical manifestation of this interaction is diabetic dyslipidemia, characterized by elevated triglycerides, low high density lipoprotein cholesterol (HDL-C), and ...
Klaus G. Parhofer
doaj   +1 more source

Dynamic, Interpretable, Machine Learning-Based Outcome Prediction as a New Emerging Opportunity in Acute Ischemic Stroke Patient Care: A Proof-of-Concept Study. [PDF]

Stroke Res Treat
Introduction: While the machine learning (ML) model’s black‐box nature presents a significant barrier to effective clinical application, the dynamic nature of stroke patients’ recovery further undermines the reliability of established predictive scores and models, making them less suitable for accurate prediction and appropriate patient care.
Petrović I, Njegovan S, Tomašević O, Vlahović D, Rajić S, Živanović Ž, Milosavljević I, Balenović A, Jorgovanović N.   +8 more
europepmc   +2 more sources