Molecular diagnosis methods in familial hypercholesterolemia
Anatolian Journal of Cardiology, 2020 Familial hypercholesterolemia (FH) is considered the genetic cause of coronary heart disease and ischemic stroke. FH is mainly an autosomal codominant pattern-based disorder and is primarily determined by point mutations within the low-density ...
Valeriu Moldovan +2 more
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Interaction between Glucose and Lipid Metabolism: More than Diabetic Dyslipidemia [PDF]
Diabetes & Metabolism Journal, 2015 Glucose and lipid metabolism are linked to each other in many ways. The most important clinical manifestation of this interaction is diabetic dyslipidemia, characterized by elevated triglycerides, low high density lipoprotein cholesterol (HDL-C), and ...
Klaus G. Parhofer
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Construction of extremal Type II $\mathbb{Z}_{2k}$-codes [PDF]
, 2022 We give methods for constructing many self-dual $\mathbb{Z}_m$-codes and Type II $\mathbb{Z}_{2k}$-codes of length $2n$ starting from a given self-dual $\mathbb{Z}_m$-code and Type II $\mathbb{Z}_{2k}$-code of length $2n$, respectively. As an application, we construct extremal Type II $\mathbb{Z}_{2k}$-codes of length $24$ for $k=4,5,\ldots,20$ and ...
arxiv +1 more source
Relation of hyperlipidemia in serum and loss of high density lipoproteins in urine in the nephrotic syndrome [PDF]
, 1987 The mechanism leading to hyperlipidemia in the nephrotic syndrome is not fully understood but may be related in part to loss of high density lipoproteins in the urine of patients with nephrosis.
Appel +22 more
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A case report of palmar xanthoma with xanthomatous neuropathy
SAGE Open Medical Case Reports, 2021 Xanthomas are plaques or nodules consisting of an accumulation of excess lipids, resulting in the formation of foam cells in the skin or tendons. Typically, xanthomas are not accompanied by other symptoms. Here, we report a patient with a presentation of
Hyun Yi Lee, Dae Won Koo, Joong Sun Lee
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Expression of type III hyperlipoproteinemia in apolipoprotein E2 (Arg158 --> Cys) homozygotes is associated with hyperinsulinemia [PDF]
, 2002 Type III hyperlipoproteinemia (HLP) is mainly found in homozygous carriers of apolipoprotein E2 (apoE2, Arg158-->Cys). Only a small percentage (< 5%) of these apoE2 homozygotes develops hyperlipidemia, indicating that additional environmental and genetic
Beer, F. (Femke) de +7 more
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Update on Familial Hypercholesterolemia: Diagnosis, Cardiovascular Risk, and Novel Therapeutics [PDF]
Endocrinology and Metabolism, 2017 In recent studies, the reported prevalence of heterozygous familial hypercholesterolemia (FH) has been higher than in previous reports. Although cascade genetic screening is a good option for efficient identification of affected patients, diagnosis using
Sang-Hak Lee
doaj +1 more source
Hyperlipidemias in elderly patients: results from the Berlin Aging Study II (BASEII), a cross-sectional study [PDF]
, 2020 Background: Hyperlipidemias are common and the last decades have seen substantially growing evidence of their causative role in the development of atherosclerosis and subsequent cardiovascular diseases.
Buchmann, Nikolaus +6 more
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Lp(a) and inflammation: a new insight into atherosclerosis
Clinical and Translational Discovery, Volume 3, Issue 5, October 2023., 2023 Lp(a)consists of LDL‐like particles, apo(a) and OxPL. The level of Lp(a) in thehuman body is predominantly determined by genetics, with external factorshaving minimal impact. Additionally, Lp(a) levels have been found to vary amongdifferent ethnicities.
Hangyu Pan +4 more
wiley +1 more source
Apolipoprotein E: from cardiovascular disease to neurodegenerative disorders. [PDF]
, 2016 Apolipoprotein (apo) E was initially described as a lipid transport protein and major ligand for low density lipoprotein (LDL) receptors with a role in cholesterol metabolism and cardiovascular disease.
Mahley, Robert W
core +1 more source