Results 121 to 130 of about 28,027 (244)
Short‐Chain Fatty Acids: Microbial Metabolites Driving Gut‐Eye Axis Signaling
Short‐chain fatty acids generated by gut microbial fermentation link diet to ocular physiology via the gut–eye axis. Through systemic distribution, these metabolites regulate GPCR signaling, epigenetic pathways, inflammation, and angiogenesis, shaping retinal homeostasis and highlighting therapeutic potential in ocular vascular and inflammatory ...
Aleah J. Brokemond +6 more
wiley +1 more source
The role of hyperoxia in abnormal development of fetal lung
Hyperoxia is closely linked with the development of chronic lung disease of prematurity (CLD) but the fixant mechanisms whereby hyperoxia alters lung architecture in the developing lung remain largely unknown.EThOS - Electronic Theses Online ...
Bustani, Porus C, Kotecha, Sailesh
core
Lung‐Cardiovascular Interactions and Derangements in ARDS
This review proposes an anatomical near‐ and far‐field framework for lung‐cardiovascular interactions in ARDS. Grounded in pathological and biological studies, the evidence spans pulmonary vascular, right ventricular, and systemic endothelial derangements and reviews available evidence for targeted therapies.
Pablo A. Sanchez +4 more
wiley +1 more source
Pulmonary hypertension is driven by dynamic crosstalk beyond the physical connection between the heart and lung, involving neurohormonal systems, immune pathways, and peripheral organs. This review highlights how multisystem signaling contributes to disease progression and may reveal new diagnostic and therapeutic targets.
Alejandro A. Vega +4 more
wiley +1 more source
Pengaruh Hyperoxia Terhadap Susunan Syaraf Pusat
Keadaan hyperoxia pada organ tubuh, dalam keadaan alamiah, adalah tidak terjadi, keadaan ini terjadi biasanya secara buatan, misalnya. Pada penggunaan oksigen untuk pekerja caisson, penyeleman dan penerbangan, atau penggunaan untuk maksud tertentu dengan
Umar Thoriq Soleh
core
ABSTRACT Extracellular vesicles (EVs) derived from mesenchymal stem or stromal cells (MSCs) have shown therapeutic potential for acute respiratory distress syndrome (ARDS), yet reproducible and scalable methods to enhance EV yield and therapeutic potency remain limited.
Shashank Chetty +7 more
wiley +1 more source
• EV content maintains cellular homeostasis and is involved in several disease onset and progression. • miRNA export in EVs depends on: RNA‐binding proteins recognizing motif sequences and on epitranscriptomic modifications. • The disclosure of delivery mechanisms is crucial for developing personalized EV‐based therapeutic tools. ABSTRACT Extracellular
Sabrina Garbo +4 more
wiley +1 more source
Iron and Other Metal Ions in Human Health and Disease
Iron, copper, zinc, and calcium orchestrate cellular function through distinct yet cooperative mechanisms: redox‐active iron and copper cycle between oxidation states to act as Fenton catalysts and electron carriers in oxidative phosphorylation (OXPHOS); redox‐inert zinc serves as a structural component of zinc‐finger proteins and a catalytic cofactor ...
Xiaofeng Dai, Jitian Li
wiley +1 more source
ABSTRACT Pulmonary hypertension (BPD‐PH) associated with bronchopulmonary dysplasia (BPD) in preterm infants associates with high morbidity and mortality within the first 2 years of life. In a previous unbiased study, we identified a panel of 16 miRNAs in tracheal aspirates (TA) that were differentially expressed in extremely low gestational age ...
Tang Li +9 more
wiley +1 more source

