Results 111 to 120 of about 41,556 (244)

Respiratory control at high altitude: The chemoreceptor as a paragon of plasticity

The Journal of Physiology, EarlyView.
Jerome A. Dempsey
wiley   +1 more source

Perioperative Normobaric Hyperoxia Combined With Pulmonary Rehabilitation Intervention for Enhanced Short‐Term Recovery in Lung Cancer Surgery

Thoracic Cancer, Volume 17, Issue 9, May 2026.
Normobaric hyperoxia enhances antioxidant defenses and promotes tissue repair, improving functional outcomes. However, its perioperative application in lung cancer patients remains limited. Normobaric hyperoxia combined with perioperative pulmonary rehabilitation may reduce postoperative LOS and total hospitalization cost for VATS‐treated patients ...
Mei Zhou, Jiani Liu, Dan Li, Jiao Luo, Lei Li, Zhonghua Yu, Sihui Song, Guosheng Xie, Zuoyan Liu, Wei Xie, Pengfei Li, Yutian Lai, Jingsi Dong, Quan Wei, Cheng Huang   +14 more
wiley   +1 more source

Targeting Hyperoxia‐Induced Cellular Senescence in Developing Human Airway Cells: Senomorphics Versus Senolytics Versus Antioxidants

Aging Cell, Volume 25, Issue 5, May 2026.
Supplemental oxygen is critical for premature infants. While initially beneficial, even moderate hyperoxia (< 60% O2) induces detrimental cellular senescence in developing airways with long‐lasting consequences. Senotherapeutics such as Fucoidan, Dasatinib (D) + Quercetin (D + Q), and mitochondrial‐targeted antioxidant MitoQ may be beneficial in ...
Maunick Lefin Koloko Ngassie, Li Y. Drake, Yi Zhu, Yamillie Ortiz, Daniel A. Pfeffer‐Kleemann, Michael A. Thompson, Samantha K. Hamrick, Christina M. Pabelick, Y. S. Prakash   +8 more
wiley   +1 more source

Responses to altered oxygen tension are distinct between human stem cells of high and low chondrogenic capacity [PDF]

, 2016
Background Lowering oxygen from atmospheric level (hyperoxia) to the physiological level (physioxia) of articular cartilage promotes mesenchymal stem cell (MSC) chondrogenesis.
Brandon D. Markway, Brian Johnstone, Derek Bond, Devon E. Anderson, Helen E. McCarthy   +4 more
core   +4 more sources

β3‐adrenoceptor agonism exerts lung protection in a rat model of bronchopulmonary dysplasia

British Journal of Pharmacology, Volume 183, Issue 10, Page 2497-2517, May 2026.
The β3‐adrenoceptors agonist BRL37344 promotes lung maturation, preventing the progression of experimental bronchopulmonary dysplasia. Absract Background and Purpose Bronchopulmonary dysplasia (BPD) affects premature newborns, particularly those receiving supplemental oxygen therapy.
Alessandro Pini, Patrizia Nardini, Virginia Zizi, Marta Molino, Maura Calvani, Francesco Carrozzo, Rachele Amato, Daniele Guasti, Denise Biagini, Fabio di Francesco, Ludovico Silvestri, Alessandra Franceschini, Daniele Bani, Elisa Imbimbo, Luca Filippi   +14 more
wiley   +1 more source

Neonatal hyperoxia exposure leads to developmental programming of cardiovascular and renal disease in adult rats

Scientific Reports
Premature infants are often exposed to hyperoxia. However, there is limited data regarding the mechanistic underpinnings linking neonatal hyperoxia exposure and its contribution to cardio-renal dysfunction in adults born preterm.
Marissa J. DeFreitas, Elaine L. Shelton, Augusto F. Schmidt, Sydne Ballengee, Runxia Tian, PingPing Chen, Mayank Sharma, Amanda Levine, Emily Davidovic Katz, Claudia Rojas, Carolyn L. Abitbol, Juanita Hunter, Shathiyah Kulandavelu, Shu Wu, Karen C. Young, Merline Benny   +15 more
doaj   +1 more source

MicroRNA-15a/16 Regulates Apoptosis of Lung Epithelial Cells After Oxidative Stress

Molecular Medicine, 2016
Lung epithelial cell apoptosis is an important feature of hyperoxia-induced lung injury. The death receptor-associated extrinsic pathway and mitochondria-associated intrinsic pathway both mediate the development of lung epithelial cell apoptosis. Despite
Yong Cao, Duo Zhang, Hyung-Geun Moon, Heedoo Lee, Jeffrey A Haspel, Kebin Hu, Lixin Xie, Yang Jin   +7 more
doaj   +1 more source

Hyperoxia resensitizes chemoresistant human glioblastoma cells to temozolomide [PDF]

, 2012
Temozolomide (TMZ) is standard chemotherapy for glioblastoma multiforme (GBM). Intratumoral hypoxia is common in GBM and may be associated with the development of TMZ resistance.
Fung, CF, Lee, D, Lee, NP, Leung, GKK, Lui, WM, Pu, JKS, Sun, S, Wong, STS   +7 more
core   +1 more source

Microneurography on the mountain: Evaluating the role of ROS in mediating sympathoexcitation at altitude

The Journal of Physiology, EarlyView.
Johan S. Thiessen, Natalie I. Miners, Philip J. Millar   +2 more
wiley   +1 more source

Rebalancing the Neurovascular Axis: NTRK2 Isoform Equilibrium as a Determinant of Pulmonary Endothelial Regeneration

Cell Proliferation, Volume 59, Issue 5, May 2026.
Summary of the functions of the NTRK2 receptor during lung injury and regeneration. Our recent work using both human organoid and mouse disease models highlights the non‐conventional role of NTRK2 isoforms in regulating pulmonary vasculature and alveolar regeneration during bronchopulmonary dysplasia.
Gan Zhou, Cheng Tan, Yifei Miao
wiley   +1 more source