Results 101 to 110 of about 41,556 (244)

HBO‐PC Reprograms Neuroimmune Metabolism Through Disruption of the LRG1‐HIF‐1α‐IL‐6‐STAT3 Amplification Loop Attenuates Pyroptosis and Ischemia–Reperfusion Injury

CNS Neuroscience &Therapeutics, Volume 32, Issue 5, May 2026.
A mouse CIRI model was generated by middle cerebral artery occlusion. HBO‐PC and LRG1 siRNA knockdown were applied. Neurological function and molecular changes were evaluated. We confirmed that HBO‐PC reprograms neuroimmune metabolism through disruption of the LRG1‐HIF‐1α‐IL‐6‐STAT3 amplification Loop attenuates pyroptosis and ischemia–reperfusion ...
Wenying Lv, Junzhe Lv, Kexin Xiong, Shunshun Yuan, Jingyao Yang, Dazhi Guo   +5 more
wiley   +1 more source

A systematic review of neuroprotective strategies after cardiac arrest: from bench to bedside (Part I - Protection via specific pathways). [PDF]

, 2014
Neurocognitive deficits are a major source of morbidity in survivors of cardiac arrest. Treatment options that could be implemented either during cardiopulmonary resuscitation or after return of spontaneous circulation to improve these neurological ...
Applegate, Patricia M, Applegate, Richard L, Gatling, Jason W, Huang, Lei, Mangus, Dustin B, Zhang, John   +5 more
core   +2 more sources

Respiratory Syncytial Virus (RSV): A Comprehensive Overview From Basic Biology to Clinical Prevention and Control

Medicinal Research Reviews, Volume 46, Issue 3, Page 672-712, May 2026.
ABSTRACT Respiratory syncytial virus (RSV) is a common virus that causes respiratory infections, posing a serious threat, particularly to infants, the elderly, and individuals with compromised immune systems. As the leading cause of lower respiratory tract infections (LRTIs) in infants, RSV is responsible for millions of cases worldwide each year.
Jie Shi, Xiya Huang, Chunjun Ye, Yishan Lu, Yanyan Liu, Yuquan Wei, Xiawei Wei   +6 more
wiley   +1 more source

Cerebral Hemodynamic Changes During Cardiac Surgery: A Feasibility MR Study in Piglets

NMR in Biomedicine, Volume 39, Issue 5, May 2026.
Congenital heart disease surgery in infants requires cardiopulmonary bypass (CPB), which increases the risk of brain injury. Conventional heart‐lung machines (HLMs) cannot operate inside MRI scanners, limiting real‐time assessment of cerebral changes. We developed an MR‐conditional HLM and tested it in piglets during CPB.
Dominik T. Schulte, Ruth O'Gorman Tuura, Henning Richter, Michael Hofmann, Francesca del Chicca, Tobias Aigner, Christoph Loeschmann, Martina Lentini, Manuela Wieser, Frauke Seehusen, Rima Bektas, Melanie Zeilinger, Martin O. Schmiady, Marianne Schmid Daners   +13 more
wiley   +1 more source

Hyperoxia and acute lung injury

American Journal of Physiology-Lung Cellular and Molecular Physiology, 2008
to the editor: The review by Matute-Bello et al. ([15][1]) has misleading and potentially dangerous statements concerning the role of hyperoxia in human acute lung injury (ALI). Table 4 states “in normal human lungs, 100% oxygen has not induced lung injury … ” The text states that ...
Aron B, Fisher, Michael F, Beers
openaire   +3 more sources

Reduced Retinal Microvascular Density, Improved Forepaw Reach, Comparative Microarray and Gene Set Enrichment Analysis with c-jun Targeting DNA Enzyme [PDF]

, 2015
Retinal neovascularization is a critical component in the pathogenesis of common ocular disorders that cause blindness, and treatment options are limited.
Chan, Cecilia W. S, Kaplan, Warren, Khachigian, Levon M, Parish, Christopher   +3 more
core   +1 more source

Post‐mortem CT detection of fatal air embolism after aerosolized fibrin glue for bladder bleeding

Journal of Forensic Sciences, Volume 71, Issue 3, Page 1507-1512, May 2026.
Abstract Radiation‐induced hemorrhagic cystitis (RHC) is a severe complication of pelvic radiotherapy, often used to treat various pelvic malignancies. Despite multiple therapeutic options, including conservative and invasive interventions, the optimal management remains uncertain. We report the case of a 76‐year‐old male with pulmonary emphysema and a
Beatrice Benedetti, Nazario Foschi, Caterina Pesaresi, Tommaso Tartaglione, Matteo Mancino, Alberto Chighine, Fabio De‐Giorgio   +6 more
wiley   +1 more source

Hyperoxia exposure promotes endothelial–mesenchymal transition and inhibits regulatory T cell function in human pulmonary microvascular endothelial cells

Frontiers in Pediatrics
ObjectiveThis study aims to investigate the effects of hyperoxia exposure on TGF-β1-induced endothelial-mesenchymal transition (EndoMT) and regulatory T cell (Treg)—mediated immunomodulation in human pulmonary microvascular endothelial cells (HPMECs ...
Yifan Sun, Chongbing Yan, Yibo Liu, Yating Lin, Bowen Weng, Xiaohui Gong, Cheng Cai   +6 more
doaj   +1 more source

Hyperoxia and salicylate metabolism in rats

Journal of Pharmacy and Pharmacology, 1990
Abstract Following the administration of aspirin to rats by gavage, both 2,3- and 2,5-dihydroxybenzoate appeared in the plasma. The concentration of the 2,3-dihydroxybenzoate was significantly higher in animals exposed to 100% O2 for 60 h than in air breathing controls.
M J, O'Connell, N R, Webster
openaire   +2 more sources

No effect of glutamine supplementation and hyperoxia on oxidative metabolism and performance during high-intensity exercise. [PDF]

, 2008
addresses: Health and Biology, Liverpool Hope University, Liverpool, UK. marwoods@hope.ac.uktypes: Comparative Study; Journal ArticleThis is an Author's Accepted Manuscript of an article published in Journal of Sports Sciences, 2008, Vol.
Adams R. P., Ahmed A., Bangsbo J., Beaver W. L., Bell C., Bendahan D., Bergmeyer H., Bruce M., Constantin-Teodosiu D., Dawson K. D., Dawson K. D., Fei Y. J., Gibala M. J., Gibala M. J., Gibala M. J., Gibala M. J., Gurd B. J., Hankard R. G., Hargreaves M., Hogan M. C., Howarth K. R., Howlett R. A., Howlett R. A., Jeukendrup A., Jo Bowtell, Knight D. R., Linnarsson D., Linossier M. T., Marwood S., Parolin M. L., Prieur F., Prieur F., Richardson R. S., Richardson R. S., Roberts P. A., Sahlin K., Savasi I., Simon Marwood, Stellingwerff T., Stellingwerff T., Timmons J. A., Timmons J. A., Timmons J. A., Timmons J. A., Timmons J. A., Tschakovsky M. E., Varnier M., Vøllestad N. K., Wagenmakers A. J., Wilkerson D. P.   +49 more
core   +2 more sources