Results 101 to 110 of about 19,463 (207)

The Effect of Hyperoxia on Nitric Oxide Metabolism in the Skeletal Muscle of Male Type 2 Diabetic Rats

Endocrinology, Diabetes & Metabolism
Introduction Hypoxia is involved in the pathophysiology of type 2 diabetes (T2D), and oxygen therapy (hyperoxia) has been proposed for managing T2D. As a side effect, hyperoxia increases nitric oxide (NO) metabolism and decreases NO bioavailability. This
Mahdis Mousavi, Sajad Jeddi, Reza Norouzirad, Asghar Ghasemi   +3 more
doaj   +1 more source

FAM134B deletion exacerbates apoptosis and epithelial-to-mesenchymal transition in rat lungs exposed to hyperoxia

iScience
Summary: Oxygen therapy is widely used in clinical practice; however, prolonged hyperoxia exposure may result in hyperoxic acute lung injury (HALI). In this study, we investigated the role of FAM134B in hyperoxia-induced apoptosis, cell proliferation ...
Hong Guo, Rong-Rong Huang, Shan-Shan Qu, Ying Yao, Su-Heng Chen, Shao-Li Ding, Yu-Lan Li   +6 more
doaj   +1 more source

Acute intermittent hypercapnic hypoxia augments left ventricular contractility

The Journal of Physiology, Volume 604, Issue 16, Page 6840-6857, 15 August 2026.
Abstract figure legend Twenty‐four healthy adults were studied to determine the effects of an acute session of 40 min of intermittent hypercapnic hypoxia on cardiac performance. Cardiac function was assessed via echocardiography at rest and during graded stages of lower‐body negative pressure before and after the intervention to quantify load ...
Scott F. Thrall, Alex M. Williams, Philip J. Millar, Megan L. Lance, Brooke M. Shafer, Conan L. H. Shing, Jordan D. Bird, Christopher R. West, Glen E. Foster   +8 more
wiley   +1 more source

Supplemental oxygen induced cardiovascular pathophysiology in an end‐of‐life care model in mice

Physiological Reports, Volume 14, Issue 15, August 2026.
Abstract Supplemental oxygen in critical care patients is associated with increased mortality. We previously reported hyperoxia‐induces cardiac pathophysiology influenced by age, metabolic status, sex, and duration of exposure. The present study investigated the dose‐dependent effects of oxygen on cardiac remodeling in very aged mice (>100 weeks), a ...
Rohan Cheruku, Drithi Chidanand, Sashank Rangarajan, Nishank Rangarajan, Siva Kumar Panguluri   +4 more
wiley   +1 more source

Hyperoxia—a Wolf in Sheep's Clothing? [PDF]

Journal of Cardiothoracic and Vascular Anesthesia, 2019
Dominik P. Guensch, Jan-Oliver Friess, Balthasar Eberle, Gabor Erdoes   +3 more
openaire   +3 more sources

Adaption to Hyperoxia [PDF]

Journal of Clinical Investigation, 1974
Gloria D. Massaro, Donald Massaro
openaire   +1 more source

Bench evidence, bedside uncertainty: hyperoxia, mechanical ventilation and lung injury. [PDF]

Eur Respir Rev
Nadeau EE, Schwingshackl A, Sturgill JL, Waters CM.   +3 more
europepmc   +1 more source

Perioperative Hyperoxia [PDF]

Anesthesiology, 2011
Jaume Canet, F. Javier Belda
openaire   +1 more source

Dexmedetomidine Preserves Hippocampal Neurogenesis During Recovery from Neonatal Hyperoxia in Rats. [PDF]

Cells
Endesfelder S, Bührer C, Schmitz T.
europepmc   +1 more source

Neonatal Exposure to Di(2-ethylhexyl) Phthalate Is Associated with Lung Injury in a Rat Model of Chronic Lung Disease of Prematurity. [PDF]

Toxics
Perveen S, Lou L, Alim S, Akselrod A, Zhao C, Sen N, Deutschman CS, Stroustrup A.   +7 more
europepmc   +1 more source