Results 81 to 90 of about 28,027 (244)

Effects of nocturnal periodic breathing on sympathetic nerve activity and ventilatory control at high altitude: a randomised, crossover study

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the randomised crossover study investigating the effects of nocturnal periodic breathing (nPB) on sympathetic activity and ventilatory acclimatisation in hypobaric hypoxia equivalent to 4000 m altitude. Participants completed two 3‐day sojourns where nPB was inhibited by increasing inspiratory CO2 fraction ...
Johanna Roche, James P. Fisher, Peter Rasmussen, Abubaker Ibrahim, Philip N. Ainslie, Rachel Turner, Giovanni Vinetti, Matteo Cesari, Michael Furian, Ambra Stefani, Nikolaus Netzer, Hannes Gatterer, Birgit Högl, Christoph Siebenmann   +13 more
wiley   +1 more source

Mechanistic advances of hyperoxia-induced immature brain injury

Heliyon
The impact of hyperoxia-induced brain injury in preterm infants is being increasingly investigated. However, the parameters and protocols used to study this condition in animal models lack consistency.
Yue Song, Changqiang Yang
doaj   +1 more source

Severe hyperoxia increases liver haemopoiesis.

, 2014
A) Haematoxylin-eosin staining of neonatal rat livers exposed to moderate and severe hyperoxia. a) ambient air; b) 60% hyperoxia; c) 95% hyperoxia. Arrows indicate haemopoietic foci. Scale bar: 200 µm, magnification 10x. B) Anti-ki67 immunohistochemistry
Guya Diletta Marconi (613851), Patrizia Zaramella (613856), Arben Dedja (613857), Raffaele De Caro (613858), Marianna De Colli (613853), Valentina Di Valerio (613854), Andrea Porzionato (613859), Susi Zara (613852), Veronica Macchi (450893), Monica Rapino (613855)   +9 more
core   +1 more source

Born early, age fast: Consequences of premature birth on chronic disease and accelerated ageing

The Journal of Physiology, EarlyView.
Abstract figure legend ELGANs are exposed to several postnatal pro‐oxidant stressors, including ambient and supplemental oxygen, mechanical ventilation, infections, hyperalimentation, excessive glucocorticoids and intermittent hypoxia. Since endogenous antioxidant defences are underdeveloped, this imbalance promotes oxidative stress and inflammation ...
Estelle B. Gauda, Julijana Ivanovska, Dwayne Mascarenhas, Jeffrey Antwi, Atefeh Mohammadi, Bonny Jasani   +5 more
wiley   +1 more source

Deletion of soluble epoxide hydrolase attenuates mice Hyperoxic acute lung injury

BMC Anesthesiology, 2018
Background Recent studies reported that soluble epoxide hydrolase (sEH) plays an important role in lung diseases. However, the role of sEH in hyperoxia-induced ALI is unclear.
Li-Ping Liu, Bin Li, Tian-Kui Shuai, Lei Zhu, Yu-Min Li   +4 more
doaj   +1 more source

No effect of hyperoxia on outcome following major trauma

, 2019
Martin Harpsø,1,2 Asger Granfeldt,3 Bo Løfgren,1,4,5 Charles D Deakin6 1Research Center for Emergency Medicine, Aarhus University Hospital, Aarhus, Denmark; 2Department of Internal Medicine, Regional Hospital of Horsens, Horsens, Denmark ...
Deakin CD, Granfeldt A, Harpsø M, Løfgren B   +3 more
core  

PKR-dependent CHOP induction limits hyperoxia-induced lung injury

, 2011
Supplemental O2is commonly employed in patients with respiratory failure; however, hyperoxia is also a potential contributor to lung injury. In animal models, hyperoxia causes oxidative stress in the lungs, resulting in increased inflammation, edema, and
William A. Altemeier, Gustavo Matute-Bello, Teal S. Hallstrand, Alison J. Eastman, Tricia I. Lozon, Peter Chen   +5 more
core   +1 more source

Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes

The Journal of Physiology, EarlyView.
Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone, Luciane H. Gargaglioni   +1 more
wiley   +1 more source

Elevated carotid body tonic activity contributes to ventilatory acclimatization and de‐acclimatization to high altitude at rest and during exercise

The Journal of Physiology, EarlyView.
Abstract figure legend Participants spent 13 days at high altitude (3800 m), where the reduced inspired oxygen pressure (↓PiO2$ \downarrow {P_{{\mathrm{i}}{{\mathrm{O}}_2}}}$) which elicited ventilatory acclimatization and increased inhibition of ventilation by transient hyperoxia (ΔV̇E$\Delta {\dot V_{\mathrm{E}}}$).
Ayechew A. Getu, L. Madden Brewster, Travis D. Gibbons, James D. Anholm, Michael Stembridge, Philip N. Ainslie, Jay M. J. R. Carr   +6 more
wiley   +1 more source

Decreased AMP‐activated protein kinase (AMPK) function and protective effect of metformin in neonatal rat pups exposed to hyperoxia lung injury

Physiological Reports, 2020
We investigated the hypothesis that exposure of lungs at the saccular stage of development to hyperoxia leads to persistent growth arrest and dysfunction of 5’AMP‐activated protein kinase (AMPK), a key energy sensor in the cell.
Abha Yadav, Ujala Rana, Teresa Michalkiewicz, Ru‐Jeng Teng, Girija G. Konduri   +4 more
doaj   +1 more source