Results 61 to 70 of about 28,027 (244)

The Effect of Hyperoxia on Central and Peripheral Factors of Arm Flexor Muscles Fatigue Following Maximal Ergometer Rowing in Men

Frontiers in Physiology, 2022
PurposeThis study evaluates the effect of hyperoxia on cerebral oxygenation and neuromuscular fatigue mechanisms of the elbow flexor muscles following ergometer rowing.MethodsIn 11 competitive male rowers (age, 30 ± 4 years), we measured near-infrared ...
Stefanos Volianitis, Peter Rasmussen, Nicolas C. Petersen, Niels H. Secher   +3 more
doaj   +1 more source

C-Abl Is Required for the Development of Hyperoxia-Induced Retinopathy [PDF]

, 2001
The requirement for the nonreceptor tyrosine kinase c-abl in the pathogenesis of retinopathy of prematurity (ROP) was examined using the mouse model for ROP and c-abl–deficient mice.
Goff, Stephen P., Rosemary D. Higgins, Irene Nunes, Zanetta, Lucia, Nunes, Irene, Peter Shamamian, Lucia Zanetta, Shamamian, Peter, Stephen P. Goff, Higgins, Rosemary D.   +9 more
core   +1 more source

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

Journal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed, Sara El Moshy, Israa Ahmed Radwan, Dina Rady, Aiah A. El‐Rashidy, Marwa M. S. Abbass, Christof E. Dörfer   +6 more
wiley   +1 more source

TXNIP mediates ferroptosis in a bronchopulmonary dysplasia mouse model by regulating the SLC7A11/GPX4 pathway

Scientific Reports
Bronchopulmonary dysplasia (BPD) is one of the most common respiratory diseases in preterm infants. Studies have shown that ferroptosis is involved in the pathogenesis of BPD, and thioredoxin-interacting protein (TXNIP)-mediated oxidative stress also ...
Dongzhui Chen, Feifei Yin, Pin Yang, Wanrong Xia, Yi Huang, Yue Feng, Li Yang, Shuqiang Lin, Qiuyue Zhang   +8 more
doaj   +1 more source

Extracellular Signal-Regulated Kinase 1 Alone Is Dispensable for Hyperoxia-Mediated Alveolar and Pulmonary Vascular Simplification in Neonatal Mice

Antioxidants, 2022
Bronchopulmonary dysplasia (BPD) is a morbid lung disease distinguished by lung alveolar and vascular simplification. Hyperoxia, an important BPD causative factor, increases extracellular signal-regulated kinases (ERK)-1/2 expression, whereas decreased ...
Renuka T. Menon, Shyam Thapa, Amrit Kumar Shrestha, Roberto Barrios, Binoy Shivanna   +4 more
doaj   +1 more source

Deletion of TXNIP decreases nitrative stress under normoxia and hyperoxia.

, 2014
A) Retinas of TKO showed significantly less nitrotyrosine levels at normoxia or hyperoxia compared to WT. B) TKO showed higher eNOS mRNA level in normoxia. Hyperoxia significantly reduced eNOS mRNA levels.
Adviye Ergul (19736), Mohammed A. Abdelsaid (287140), Suraporn Matragoon (287137), Azza B. El-Remessy (287151)   +3 more
core   +1 more source

β3 Adrenoceptor Agonism Prevents Hyperoxia-Induced Colonic Alterations [PDF]

, 2023
Oxygen level is a key regulator of organogenesis and its modification in postnatal life alters the maturation process of organs, including the intestine, which do not completely develop in utero.
Carrozzo, Francesco, Virginia Zizi, Francesco Carrozzo, Zizi, Virginia, Camilla Fazi, Crociani, Olivia, Fazi, Camilla, Patrizia Nardini, Giacomo Cavallaro, Olivia Crociani, Filippi, Luca, Pini, Alessandro, Laura Calosi, Marta Molino, Luca Filippi, Maura Calvani, Calvani, Maura, Calosi, Laura, Giorgia Giuseppetti, Alessandro Pini, Nardini, Patrizia, Molino, Marta   +21 more
core   +1 more source

Uncovering the impact of the cardiovascular system on cerebrovascular health using MRI

Experimental Physiology, EarlyView.
Abstract Human cerebrovasculature is finely tuned to enable local changes in blood flow to meet the brain's demands, whilst protecting the brain from systemic changes in blood pressure, both acutely during a heartbeat and chronically over time. This review summarises cerebrovascular structure and function, their role in disease and neurodegeneration ...
Ian D. Driver, Kevin Murphy
wiley   +1 more source

Amphiregulin Exerts Proangiogenic Effects in Developing Murine Lungs

Antioxidants
Interrupted lung angiogenesis is a hallmark of bronchopulmonary dysplasia (BPD); however, druggable targets that can rescue this phenotype remain elusive.
Shyam Thapa, Nithyapriya Shankar, Amrit Kumar Shrestha, Monish Civunigunta, Amos S. Gaikwad, Binoy Shivanna   +5 more
doaj   +1 more source

Influence of facial cooling on carotid body tonic activity and sensitivity

Experimental Physiology, EarlyView.
Abstract Facial cooling can increase ventilation and augment the hypoxic ventilatory response. Whole body cooling increases both carotid body tonic activity and sensitivity; however, whether isolated facial cooling induces similar carotid body hyperexcitability was unknown.
Robyn Morley, Liam D. Corr, Elliott J. Jenkins, Joseph A. Killick, Travis D. Gibbons, Joshua C. Tremblay   +5 more
wiley   +1 more source