Results 91 to 100 of about 41,556 (244)
The carotid body as a putative therapeutic target for the treatment of neurogenic hypertension [PDF]
, 2013 In the spontaneously hypertensive (SH) rat, hyperoxic inactivation of the carotid body (CB) produces a rapid and pronounced fall in both arterial pressure and renal sympathetic nerve activity (RSA).
Abdala, Ana P +7 more
core +2 more sources
The Journal of Physiology, EarlyView.Abstract figure legend High‐altitude acclimatisation increases muscle sympathetic nerve activity (MSNA) via activation of the arterial chemoreflex, pulmonary arterial baroreceptors and resetting of the sympathetic vascular baroreflex. However attempting to silence these mechanisms only partially normalises MSNA, implicating other contributory ...
Liam D. Corr +15 more
wiley +1 more source
Mechanistic advances of hyperoxia-induced immature brain injury
HeliyonThe impact of hyperoxia-induced brain injury in preterm infants is being increasingly investigated. However, the parameters and protocols used to study this condition in animal models lack consistency.
Yue Song, Changqiang Yang
doaj +1 more source
Deletion of soluble epoxide hydrolase attenuates mice Hyperoxic acute lung injury
BMC Anesthesiology, 2018 Background Recent studies reported that soluble epoxide hydrolase (sEH) plays an important role in lung diseases. However, the role of sEH in hyperoxia-induced ALI is unclear.
Li-Ping Liu +4 more
doaj +1 more source
Hypoxia‐induced vulnerability of the somatosensory nervous system
The Journal of Physiology, EarlyView.Abstract figure legend Sensory neurons are highly energy dependent and rely on sufficient oxygen availability to maintain metabolic stability and effective neurocommunication. Within the somatosensory system, even modest reductions in tissue oxygen tension impair neuronal respiration, forcing a shift toward less efficient metabolic pathways that ...
Jack Corbett, Richard P. Hulse
wiley +1 more source
Physiological Reports, 2020 We investigated the hypothesis that exposure of lungs at the saccular stage of development to hyperoxia leads to persistent growth arrest and dysfunction of 5’AMP‐activated protein kinase (AMPK), a key energy sensor in the cell.
Abha Yadav +4 more
doaj +1 more source
Hypoxia, hyperoxia and breathing
Journal of Biosciences, 2006 This short Commentary has been limited to a few of several studies. They clearly indicate that the mechanisms involved in the effects of hypoxia and hyperoxia on the ventilatory control and particularly on theintegrative respiratory centres are far from being completely understood and are now believed to be more complex than what was postulated 40 ...
openaire +2 more sources
Advanced Materials Technologies, Volume 11, Issue 9, 6 May 2026.This review explores the integration of microfluidic technology with organoid systems as an innovative platform for studying menopausea complex multi‐organ condition. By enabling precise simulation of inter‐organ communication and hormone responses, microfluidic organoids offer a physiologically relevant model for investigating menopausal syndrome and ...
Qianyi Zhang +4 more
wiley +1 more source
Celecoxib Protects Hyperoxia-Induced Lung Injury via NF-κB and AQP1
Frontiers in Pediatrics, 2019 Objective: There is an increasing incidence of bronchopulmonary dysplasia (BDP) in preterm infants in China, which is the key issue affecting their survival rate and life quality.
Dongyun Liu +8 more
doaj +1 more source
Clinical Cardiology, Volume 49, Issue 5, May 2026.In this large‐scale UK Biobank analysis, elevated plasma EDA2R was associated with a 74% higher risk of cardiovascular disease and a 177% higher risk of all‐cause mortality, with a 7.2‐year loss in life expectancy in the highest EDA2R group, suggesting its potential as a prognostic biomarker and therapeutic target.
Ziqing Ruan +6 more
wiley +1 more source