Results 51 to 60 of about 20,336 (222)

Association between serum α‐Klotho levels and severity of periodontitis in a representative U.S. population

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Periodontitis, a chronic inflammatory disease, is linked to systemic conditions such as cardiovascular and kidney disease. Serum α‐Klotho, an anti‐aging protein with anti‐inflammatory properties, has been associated with systemic diseases, but its role in periodontitis is unclear.
Hamoun Sabri   +6 more
wiley   +1 more source

Difficulties in correcting hyperphosphatemia in patients with chronic renal failure. A place of noncalcium-containing phosphate-binding drugs [PDF]

open access: yesТерапевтический архив, 2016
The review considers the current views of the mechanisms of hyperphosphatemia in patients with chronic renal failure. It shows indications for the use of different classes of phosphate-binding drugs to correct hyperphosphatemia.
Yu S Milovanov   +2 more
doaj  

The role of FGF23/Klotho in mineral metabolism and chronic kidney disease [PDF]

open access: yes, 2013
Chronic kidney disease (CKD) is a global health burden of growing incidence and prevalence. As renal function declines disturbances in mineral metabolism, such as hyperphosphatemia and secondary hyperparathyroidism, inevitably develop. These metabolic
Olauson, Hannes
core   +1 more source

Monogenic and syndromic obesity in children: Clinical recognition, genetics, and precision management

open access: yesPediatric Investigation, EarlyView.
Monogenic and syndromic obesity in children often arises from defects in the leptin–melanocortin pathway. Understanding these rare genetic causes not only clarifies mechanisms of appetite regulation but also enables precision therapies, offering hope beyond lifestyle interventions.
Hadel Khalil   +2 more
wiley   +1 more source

Implementation and effectiveness of an intensive education program on phosphate control among hemodialysis patients: a non-randomized, single-arm, single-center trial

open access: yesBMC Nephrology, 2021
Background Hyperphosphatemia is a common complication in patients on maintenance hemodialysis. Patients’ adherence to phosphorus control can be improved by consistent education.
Jinmei Yin   +4 more
doaj   +1 more source

A Controlled Increase in Dietary Phosphate Elevates BP in Healthy Human Subjects. [PDF]

open access: yes, 2018
Background Despite epidemiologic evidence for increased cardiovascular morbidity and mortality associated with both high dietary and serum phosphate in humans with normal renal function, no controlled phosphate intervention studies of systemic ...
Bestmann, Lukas   +4 more
core  

Postoperative hyperphosphatemia significantly associates with adverse survival in colorectal cancer patients [PDF]

open access: yes, 2013
BACKGROUND: Hyperphosphatemia has been implicated in the development and treatment of various cancers. However, whether it can be used as a direct prognostic marker of colorectal cancer (CRC) has remained unexplored.
Guiles, Fran   +8 more
core   +1 more source

Machine learning‐based predictive models versus traditional risk scores in hemodialysis patients with comorbid urolithiasis

open access: yesPrecision Medical Sciences, EarlyView.
Machine learning‐based predictive models outperform traditional risk scores in hemodialysis patients with comorbid urolithiasis by capturing nonlinear, dialysis‐specific interactions. These approaches enable more accurate prediction of stone recurrence, sepsis, hospitalization, and mortality, supporting personalized risk stratification and precision ...
Dipal Chaulagain   +4 more
wiley   +1 more source

Use of phosphate binders in end-stage renal disease: An experience from a secondary care hospital in United Arab Emirates

open access: yesJournal of Pharmacy and Bioallied Sciences, 2019
Objective: Hyperphosphatemia in end-stage renal disease (ESRD) is associated with many serious patient-level consequences including cardiovascular events and mortality.
Syed Arman Rabbani   +4 more
doaj   +1 more source

Tumor lysis syndrome in an extraskeletal osteosarcoma: a case report and review of the literature [PDF]

open access: yes, 2017
BACKGROUND: This case report describes a spontaneous tumor lysis syndrome due to a rare solid tumor. CASE PRESENTATION: A 65-year-old white woman had tumor lysis syndrome, which represent a dangerous oncological emergency.
Giulia Malaguarnera   +5 more
core   +1 more source

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