Results 51 to 60 of about 13,452 (217)
MedComm – Biomaterials and Applications, Volume 5, Issue 1, March 2026.Vascular calcification significantly elevates cardiovascular risk in CKD patients, yet no effective therapies exist to halt its progression. We developed a dual targeting nanoplatform Ti3C2/RANKL/OCN/Cyanidin (TROC) for the targeted delivery of cyanidin against vascular calcification.
Li Yin +10 more
wiley +1 more source
European Journal of Haematology, Volume 116, Issue 2, Page 129-141, February 2026.ABSTRACT Relapsed/refractory (R/R) mantle cell lymphoma (MCL) remains a therapeutic challenge, particularly in patients with high‐risk features or prior exposure to Bruton's tyrosine kinase inhibitors (BTKis). The advent of T‐cell–redirecting immunotherapies, including chimeric antigen receptor T‐cell (CAR‐T) therapy and bispecific antibodies (BsAbs ...
Santino Caserta +10 more
wiley +1 more source
The serum level of the morphogenetic protein fibroblast growth factor 23 (FGF-23) as a marker for the efficiency of hyperphosphatemia therapy with phosphate-binding agents in chronic kidney disease [PDF]
Терапевтический архив, 2016 Aim. To study whether the excessive production of serum fibroblast growth factor 23 (FGF-23) may be reduced with phosphate-binding agents to treat hyperphosphatemia in patients with Stage VD chronic kidney disease (CKD). Subjects and methods.
N A Mukhin +4 more
doaj
Novel Treatments from Inhibition of the Intestinal Sodium–Hydrogen Exchanger 3
International Journal of Nephrology and Renovascular Disease, 2021 Csaba P Kovesdy,1 Adebowale Adebiyi,2 David Rosenbaum,3 Jeffrey W Jacobs,3 L Darryl Quarles1 1Division of Nephrology, University of Tennessee Health Science Center, Memphis, TN, USA; 2Department of Physiology, University of Tennessee Health Science ...
Kovesdy CP +4 more
doaj
eLife, 2022 Elevations in plasma phosphate concentrations (hyperphosphatemia) occur in chronic kidney disease (CKD), in certain genetic disorders, and following the intake of a phosphate-rich diet.
Brian Czaya +11 more
doaj +1 more source
The FASEB Journal, Volume 40, Issue 1, 15 January 2026.Ay et al. investigated the cellular mechanisms behind the role of lysophosphatidic acid (LPA) in FGF23 production. They revealed that LPA cooperates with 1,25‐dihydroxyvitamin D (1,25D), that is, the bioactive form of vitamin D known to stimulate FGF23 synthesis. This synergy entails MAPK signaling and the induction of the gene encoding the interleukin‐
Birol Ay +7 more
wiley +1 more source
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Advanced Functional Materials, Volume 36, Issue 1, 2 January 2026.Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth +2 more
wiley +1 more source
Linchuang shenzangbing zazhi, 2020 Objective To evaluate the efficacy and safety of ferric citrate in treatment of hyperphosphatemia in patients with chronic kidney disease（CKD）,and provide evidence-based basis for clinical medication.Methods The literature on randomized controlled trials（
WANG Shan-shan, WEN Tong, ZHANG Xin-zhou
doaj
Central Diabetes Insipidus in Suprasellar Germ Cell Tumor Paradoxically Presenting With Oliguria
Clinical Case Reports, Volume 14, Issue 1, January 2026.ABSTRACT Central diabetes insipidus may present as oliguric acute kidney injury (AKI), particularly in patients with communication difficulties. While polyuria is common in AKI recovery, persistent or unexplained hypernatremia should prompt suspicion for alternative diagnoses such as unmasked diabetes insipidus to ensure timely recognition and ...
Karen Kin Nam Wong +2 more
wiley +1 more source
71 Analysis From the OPTIMIZE Trial: Evaluating Options for Initiating Tenapanor in CKD Patients on Dialysis With Hyperphosphatemia [PDF]
, 2022 openalex +1 more source