Results 161 to 170 of about 129,353 (325)
ABSTRACT Background Elexacaftor/tezacaftor/ivacaftor (ETI) is a current standard therapy for pediatric cystic fibrosis (CF). Multiple‐breath washout 129Xe MRI (MBW Xe‐MRI) is improved following 1 month of treatment. However, the utility of MBW Xe‐MRI over extended ETI treatment and its comparison to single‐breath Xe‐MRI and pulmonary function tests ...
Faiyza S. Alam +6 more
wiley +1 more source
ABSTRACT Background The pulsatile expansion of pulmonary vessels carries dynamic cardiopulmonary information that may reveal disease earlier than structural changes alone. Purpose To test (i) intra‐ and inter‐scan repeatability of dynamic vessel metrics in healthy subjects, and (ii) whether chronic obstructive pulmonary disease (COPD) and postcapillary
Julian Glandorf +10 more
wiley +1 more source
Are physiological oscillations physiological?
Abstract figure legend Mechanisms and functions of physiological oscillations. Abstract Despite widespread and striking examples of physiological oscillations, their functional role is often unclear. Even glycolysis, the paradigm example of oscillatory biochemistry, has seen questions about its oscillatory function.
Lingyun (Ivy) Xiong, Alan Garfinkel
wiley +1 more source
ABSTRACT Background Hyperpolarized 129Xe MRI faces technical challenges including low signal‐to‐noise ratio and breath‐hold constraints. Current literature focuses on proprietary deep learning methods or image‐domain enhancements. Purpose To present a comprehensive evaluation of transformer and hybrid CNN‐transformer architectures integrating dual ...
Ramtin Babaeipour +3 more
wiley +1 more source
Abstract Omega‐3 fatty acids (omega‐3s) are polyunsaturated fatty acids linked with numerous health benefits. Omega‐3s exhibit multifaceted activities through various mechanisms. Eicosapentaenoic acid (EPA) alleviates oxidative stress by lowering reactive oxygen species and improving oxidative stress in brain tissues and acts against neurodegenerative ...
Md Faruque Ahmad +12 more
wiley +1 more source
MRI for Mixing Quality in Microfluidics
Fluidic mixing in a micromixer: Paramagnetic relaxation enhancement and chemical shift differences were explored to reveal mixing quality at the small dimensions of an optically opaque y‐mixer. ABSTRACT Liquid state processes often involve mixing of process streams.
J. Götz +5 more
wiley +1 more source
ABSTRACT Purpose To explore the relationship between potentially rate‐limiting steps in lactate production and the lactate area‐under‐the‐curve (AUC) to pyruvate AUC ratio for analysis of hyperpolarized (HP) [1‐13C]‐pyruvate data. Theory and Methods Simplifying assumptions are introduced to a pharmacokinetic (PK) model with three physical compartments ...
Ryan T. Boyce +6 more
wiley +1 more source
ABSTRACT Purpose This study aimed to improve the analysis of the left ventricular (LV) blood pool hyperpolarized [1‐13C]pyruvate signal for a more reliable quantification of downstream metabolic outcome. Methods Hyperpolarized [1‐13C]pyruvate magnetic resonance spectroscopic images were acquired dynamically at 3 Tesla in 106 participants (NCT03685175).
Fatemeh Khashami +30 more
wiley +1 more source
Free‐Breathing Magnetization Transfer Imaging of the Lung at 0.55 T Using bSTAR
ABSTRACT Purpose To develop a clinically applicable method for magnetization transfer (MT) imaging of the lung at 0.55 T. Methods MT imaging of the chest was explored in healthy volunteers at 0.55 T using a self‐gated 3D half‐radial dual‐echo balanced steady‐state free precession sequence (bSTAR), a 2D multi‐slice gradient echo method (GRE) acquired in
Alexandra Braun +5 more
wiley +1 more source

