Results 51 to 60 of about 634,412 (379)

Chaos for Liouville probability densities

, 1995
Using the method of symbolic dynamics, we show that a large class of classical chaotic maps exhibit exponential hypersensitivity to perturbation, i.e., a rapid increase with time of the information needed to describe the perturbed time evolution of the ...
A. J. Lichtenberg, A. N. Kolmogorov, A. N. Kolmogorov, A. Peres, B. O. Koopman, C. E. Shannon, C. E. Shannon, C. E. Shannon, C. M. Caves, C. M. Caves, C. M. Caves, Carlton M. Caves, D. S. Ornstein, D. Welsh, E. Borel, E. Borel, E. T. Jaynes, E. T. Jaynes, E. T. Jaynes, G. J. Chaitin, H. Spohn, J. Ford, J. P. Crutchfield, M. V. Berry, R. Landauer, R. Landauer, R. Schack, R. Schack, R. Schack, Rüdiger Schack, V. I. Arnold, V. M. Alekseev, W. H. Zurek, W. H. Zurek   +33 more
core   +1 more source

The use of drug calendars for the diagnosis of cutaneous drug eruptions in the age of electronic medical records [PDF]

, 2020
A morbilliform drug eruption is the most common condition leading to a dermatology consultation for a patient in the hospital. Timing is an important diagnostic tool since the onset of a skin rash usually takes place within days-to-weeks of the start of ...
Cohen, Philip R, Grossman, Marc E
core  

Immune checkpoint inhibitor-induced severe epidermal necrolysis mediated by macrophage-derived CXCL10 and abated by TNF blockade

Nature Communications
Immune checkpoint inhibitors (ICI) represent new anticancer agents and have been used worldwide. However, ICI can potentially induce life-threatening severe cutaneous adverse reaction (SCAR), such as Stevens-Johnson syndrome/toxic epidermal necrolysis ...
Chun-Bing Chen, Shuen-Iu Hung, John Wen-Cheng Chang, Chan-Keng Yang, David Hui-Kang Ma, Yu-Chuan Teng, Chun-Wei Lu, Wei-Ti Chen, Hsiao-Yin Yang, Cheng-Chang Tsai, Chih Liang Wang, Pin-Hsuan Chiang, Jennifer Wu, Ya-Wen Tsai, Lai-Ying Lu, Yang Yu-Wei Lin, Rosaline Chung-Yee Hui, Fu-Mei Hsieh, Chao-Kai Hsu, Chaw-Ning Lee, Yi-Ju Chen, Chih-Chiang Chen, Yilei Cui, Hung-Chih Hsu, Ya-Ching Chang, Chih-Jung Chang, Ho-Chen Lin, Chee Jen Chang, Yu-Jr Lin, Cheng-Lung Ku, Chuang-Wei Wang, Wen-Hung Chung   +31 more
doaj   +1 more source

Mas-Related G Protein-Coupled Receptor-X2 (MRGPRX2) in Drug Hypersensitivity Reactions

Frontiers in Immunology, 2018
The human ortholog MRGPRX2 and the mice ortholog, Mrgprb2 are activated by basic secretagogues and neurokinins. A number of commonly used small-molecule drugs (e.g., neuromuscular blocking agents, fluoroquinolones, vancomycin) have been recently shown to
G. Porębski, K. Kwiecien, Magdalena Pawica, M. Kwitniewski   +3 more
semanticscholar   +1 more source

The Development of Hypersensitivity Reactions in the Pediatric Population: A Review [PDF]

, 2019
Over the past several years, pediatric allergies have come to the forefront of many studies. Reports of immune-mediated hypersensitivity in younger patients have grown and led to an interest researching the causes of pediatric hypersensitivities.
Burns, Heather
core   +1 more source

Key role for inhibins in effective T cell activation, migration and Th17 differentiation

FEBS Open Bio, EarlyView.
Activins/inhibins modulate immune responses. Here, we show that inhibins can be produced very early after T cell activation and can act in an autocrine way, favoring Th1 versus Th17 differentiation and CCL19/CCL21 mediated migration. Recombinant inhibin A can restore the Th1/Th17 balance, highlighting the role of inhibins as key regulators of T cell ...
Sandra Ortega‐Francisco, Roxana Olguín‐Alor, Lizbeth Bolaños‐Castro, Alexandra Morales‐Cruz, Marisol De La Fuente‐Granada, Gloria Soldevila   +5 more
wiley   +1 more source

Clinical Characteristics and Disease Burden of Patients with Moderate-to-Severe Generalized Pustular Psoriasis Flares in Taiwan

Dermatology and Therapy
Introduction Generalized pustular psoriasis (GPP) is a rare and severe psoriasis subtype characterized by the rapid onset of coalescing sterile pustules over broad body areas and systemic inflammation.
Chun-Wei Lu, Chien-Yu Tseng, Chuang-Wei Wang, Shang-Hung Lin, Chun-Bing Chen, Rosaline Chung-Yee Hui, Ching-Chi Chi, Yu-Huei Huang, Chih-Hung Lee, Fang-Ju Lin, Wen-Hung Chung   +10 more
doaj   +1 more source

Allergic asthma and rhinitis comorbidity [PDF]

Vojnosanitetski Pregled, 2015
nema
Zvezdin Biljana, Hromiš Sanja, Kolarov Violeta, Milutinov Senka, Zarić Bojan, Jovančević Ljiljana, Ilić Miroslav   +6 more
doaj   +1 more source

Systemic T Cell Receptor Profiling Reveals Adaptive Immune Activation and Potential Immune Signatures of Diagnosis and Brain Atrophy in Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin, Sang Bin Hong, Yong Woo Shin, Inpyeong Hwang, Jaeseong Oh, Jihyeon Choi, Narae Kim, Jangsup Moon, Keun‐Hwa Jung, Kyung‐Il Park, Ki‐Young Jung, Kon Chu, Sang Kun Lee   +12 more
wiley   +1 more source

Hydrolyzed Protein Formula for Allergy Prevention in Preterm Infants: Follow-Up Analysis of a Randomized, Triple-Blind, Placebo-Controlled Study

Frontiers in Pediatrics, 2020
Background: Allergic diseases are a major public health burden worldwide. Evidence suggests that early nutrition might play a key role in the future development of allergies and the use of hydrolyzed protein formulas have been proposed to prevent ...
Antonio Di Mauro, Maria Elisabetta Baldassarre, Giulia Brindisi, Anna Maria Zicari, Martina Tarantini, Nicla Laera, Manuela Capozza, Raffaella Panza, Silvia Salvatore, Licia Pensabene, Margherita Fanelli, Nicola Laforgia   +11 more
doaj   +1 more source