Results 141 to 150 of about 172,514 (308)

Imaging of Abdominal Complications in Children With Acute Lymphoblastic Leukaemia

Journal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Acute lymphoblastic leukaemia (ALL) is the most common paediatric malignancy and remains one of the most common causes of cancer‐related death in children and adolescents. Five‐year overall survival rates now exceed 90% with current multidrug chemotherapeutic regimens. This improvement, coupled with the toxicity of chemotherapy, has led to the
Luke R. Holmes, Rishi S. Kotecha, Derek J. Roebuck   +2 more
wiley   +1 more source

Changing perspectives on liver transplantation in 1988. [PDF]

, 1988
After liver transplantation for cancer, there is a high incidence of disease recurrence within 18 to 36 months for most tumors, although there are a small number of long-term survivors.
Gordon, RD, Starzl, TE
core  

Biomarkers of Extracellular Matrix Remodelling Are Linked to Severity and Outcome of Advanced Chronic Liver Disease

Alimentary Pharmacology &Therapeutics, EarlyView.
Extracellular matrix (ECM) remodelling biomarkers reflect portal hypertension and disease severity in advanced chronic liver disease (ACLD). However, their predictive value for disease progression is largely restricted to compensated ACLD (cACLD). ABSTRACT Background Extracellular matrix (ECM) remodelling in advanced chronic liver disease (ACLD) is ...
Benedikt Simbrunner, Ida Falk Villesen, Georg Semmler, Lorenz Balcar, Georg Kramer, Joana Almeida Calvão, Benedikt Silvester Hofer, Mathias Jachs, Lukas Hartl, Jurij Maurer, Bernhard Scheiner, Kerstin Zinober, Rodrig Marculescu, Michael Trauner, Morten Karsdal, Thomas Reiberger, Mattias Mandorfer, Diana Julie Leeming   +17 more
wiley   +1 more source

Unstable Recompensation: An Intermediate Subtype in Patients With HBV‐Related Decompensated Cirrhosis

Alimentary Pharmacology &Therapeutics, EarlyView.
Recompensation is a heterogeneous and dynamic state in HBV‐related decompensated cirrhosis; The prognosis for patients with unstable recompensation was found to be worse compared to those with stable recompensation, but still better than patients without recompensation; Subclassification of recompensation has significant implications for prognosis and ...
Shuai Xia, Zhiying He, Xiaoning Wu, Zhongjie Hu, Chunqing Zhang, Yanqin Hao, Yongfeng Yang, Yan Huang, Wei Rao, Xiaoqian Xu, Xinyu Zhao, Jialing Zhou, Yameng Sun, Shuyan Chen, Luqi Tang, Xiaojuan Ou, Xinyan Zhao, Jidong Jia, Bingqiong Wang, Hong You   +19 more
wiley   +1 more source

Indocyanine Green Clearance Correlates With Biomarkers Reflecting Key Disease‐Driving Mechanisms in Advanced Chronic Liver Disease and Predicts Acute‐on‐Chronic Liver Failure and Death

Alimentary Pharmacology &Therapeutics, EarlyView.
Indocyanine green clearance by pulse dye densitometry correlates with portal hypertension, systemic inflammation and circulatory dysfunction in advanced chronic liver disease. While diagnostic accuracy for CSPH was limited, ICG‐R15 independently predicted decompensation and ACLF/liver‐related mortality, highlighting its prognostic value across disease ...
Mathias Jachs, Tânia Carvalho, Benedikt Simbrunner, Georg Semmler, Lukas Hartl, Lorenz Balcar, Benedikt Silvester Hofer, Paul Thöne, Nina Dominik, Georg Kramer, Christian Sebesta, Michael Schwarz, David Bauer, Albert F. Stättermayer, Matthias Pinter, Michael Trauner, Thomas Reiberger, Mattias Mandorfer   +17 more
wiley   +1 more source

Diabetes Mellitus is a Risk Factor for Hepatic Encephalopathy Following Transjugular Intrahepatic Portosystemic Shunt

Alimentary Pharmacology &Therapeutics, EarlyView.
Diabetes mellitus independently increases the risk of hepatic encephalopathy following TIPS placement in patients with cirrhosis. These findings emphasize the need for careful risk assessment in patients with cirrhosis and portal hypertension complications undergoing TIPS.
Michelle Spaan, Ellen Werner, Willemijn Dijkstra, Nicole E. Erler, Diederik Bijdevaate, Sarwa Darwish Murad, Milan J. Sonneveld, Caroline M. den Hoed, Anne van Eldere, Dave S. Sprengers, Willem‐Pieter Brouwer, Robert J. de Knegt, Harry L. A. Janssen, Kay Pieterman, Sandra Coenen, Raoel Maan, Adriaan J. van der Meer   +16 more
wiley   +1 more source

Serum Villin‐1—A Novel Marker of Gut Barrier Damage in Acutely Decompensated Cirrhosis: A Cohort Study and Validation

Alimentary Pharmacology &Therapeutics, EarlyView.
Serum villin‐1 is a non‐invasive indicator of gut barrier damage and short‐term mortality in acutely decompensated cirrhosis. Incorporating villin‐1 assessment into risk stratification methods improves prognostic accuracy by capturing an essential, yet previously overlooked component of disease progression.
David Tornai, Boglarka Balogh, Aniko Csillag, Andras Budai, Andras Kiss, Peter Antal‐Szalmas, Gabor Mehes, Lukacs Barath, Tamas Tornai, Istvan Tornai, Zsuzsanna Vitalis, Nora Sipeki, Tamas Dinya, Attila Enyedi, Florian A. Rosenberger, Wim Laleman, Minneke J. Coenraad, Ferran Aguilar, Joan Claria, Richard Moreau, Jonel Trebicka, Maria Papp, on behalf of MICROB‐PREDICT and PREDICT study group of the EASL‐CLIF consortium   +22 more
wiley   +1 more source

Post‐Banding Ulcer Bleeding After Endoscopic Ligation: Incidence, Risk Factors and Outcomes in Patients With Cirrhosis

Alimentary Pharmacology &Therapeutics, EarlyView.
A PBUB is a rare but often fatal complication of endoscopic variceal band ligation. The relevant risk factors contributing to PBUB are unknown and consequently there are no effective preemptive strategies. This study highlights kidney disease as a predictor of PBUB together with the well‐established higher risk for urgent band ligation.
Maria de Brito Nunes, Matthias Knecht, Jonas Schropp, Reiner Wiest, Jaume Bosch, Annalisa Berzigotti   +5 more
wiley   +1 more source

Spontaneous Bacterial Peritonitis Is Associated With High Mortality, Which Interacts With Antibiotic Prophylaxis in a National Cirrhosis Cohort

Alimentary Pharmacology &Therapeutics, EarlyView.
In a national cohort of newly decompensated Veterans with cirrhosis, SBP and recurrences are linked with higher death and need for liver transplant. SBP prophylaxis, whether primary or secondary, worsens resistance and interacts with mortality but not liver transplant.
Scott Silvey, Nilang Patel, Jacqueline G. O'Leary, Timothy Morgan, John D. Markley, Sofia S. Jakab, Heather Patton, Shari Rogal, Jasmohan S. Bajaj   +8 more
wiley   +1 more source

Statin Therapy Independently Reduces Mortality and Liver Complications in Patients With Cirrhosis: An Updated Systematic Review and Meta‐Analysis

Alimentary Pharmacology &Therapeutics, EarlyView.
Statin therapy in cirrhosis may confer a survival benefit while reducing the risk of hepatic decompensation and hepatocellular carcinoma. ABSTRACT Background The role of statins in cirrhosis remains controversial. Historically restricted due to safety concerns, emerging evidence highlights potential pleiotropic benefits, though effects on mortality and
Bernardo de Faria Moraes, Gustavo André Pedral Diniz Leite, Igor Boechat Silveira, Gabriel André Pedral Diniz Leite, Maria Luisa Motta Fonseca, Leonardo Corrêa Suffert, Luisa Medeiros Visentini, Luis Pedro Possapp Beis, Guilherme Grossi Lopes Cançado   +8 more
wiley   +1 more source