Results 41 to 50 of about 107,932 (308)

Portal hypertension in cirrhosis: Pathophysiological mechanisms and therapyKey points

JHEP Reports, 2021
Summary: Portal hypertension, defined as increased pressure in the portal vein, develops as a consequence of increased intrahepatic vascular resistance due to the dysregulation of liver sinusoidal endothelial cells (LSECs) and hepatic stellate cells ...
Yasuko Iwakiri, Jonel Trebicka
doaj   +1 more source

Elevated Gastric Antrum Erosions in Portal Hypertension Patients: Peptic Disease or Mucosal Congestion?

The Korean Journal of Gastroenterology, 2017
Background/Aims: Portal hypertension (PH) is a syndrome characterized by chronic increase in the pressure gradient between the portal vein and inferior vena cava. Previous studies have suggested an increased frequency of antral elevated erosive gastritis
Fernanda Cordeiro de Azevedo Conejo, Mabel Tatty Medeiros Fracassi, Maurício Saab Assef, Maurício Alves Ribeiro, Luiz Arnaldo Szutan, Fabio Gonçalves Ferreira   +5 more
doaj   +1 more source

Emerging therapies for portal hypertension in cirrhosis.

, 2016
INTRODUCTION Counteracting splanchnic vasodilatation and increased portal-collateral blood flow has been the mainstay for the treatment of portal hypertension (PH) over the past three decades.
Berzigotti, Annalisa, Bosch, Jaime, Nair, Harikumar   +2 more
core   +1 more source

Advances and challenges in cirrhosis and portal hypertension [PDF]

, 2017
Background Liver cirrhosis is the fourth cause of death in adults in Western countries, with complications of portal hypertension being responsible for most casualties.
Annalisa Berzigotti, Berzigotti, Annalisa   +1 more
core   +1 more source

Association of blood cadmium levels with all-cause and cause-specific mortality among adults with non-alcoholic fatty liver disease: a prospective cohort study

Frontiers in Public Health
BackgroundCadmium (Cd) accumulates in the body over time, damaging organs such as the liver, kidneys, and brain. Some researchers have suggested that elevated blood Cd levels may contribute to the onset and progression of nonalcoholic fatty liver disease
Congxi Xu, Congxi Xu, Zhi Li, Shirui Hao, Jian Zhang, Jinlong Li, Kuopeng Liang, Xiaojuan Wang, Yi Zhang, Yi Zhang, Guangyuan Zhao, Mengyun Bai, Dengxiang Liu, Jitao Wang   +13 more
doaj   +1 more source

The peculiarities of macroscopic status of the upper gastrointestinal tract mucosa in patients with hepatic and extrahepatic portal hypertension.

Medičnì Perspektivi, 2018
Identification of endoscopic signs of concomitant pathology of the upper gastrointestinal tract allows to determine the tactics of managing patients with different forms of portal hypertension (PG).
Yu. M. Stepanov, N. V. Chaliy, O. V. Simonova   +2 more
doaj   +1 more source

The future treatment of portal hypertension

, 2007
Increased understanding of the hyperdynamic circulation syndrome has resulted in novel therapeutic approaches, some of which have already reached clinical practice.
Lebrec, Didier, Reichen, Jürg
core   +1 more source

Effect of skeletal muscle index on post-embolization syndrome of hepatocellular carcinoma after transarterial chemoembolization

BMC Gastroenterology
Background Skeletal muscle index (SMI) is a commonly used research method for evaluating muscle mass.However, its impact on post-embolization syndrome(PES) of patients with hepatocellular carcinoma (HCC) undergoing transarterial chemoembolization (TACE ...
Xiaojuan Wang, Jitao Wang, Jinlong Li, Kuopeng Liang, Shoufang Dai, Ruikun Wang, Yi Zhang, Quan Ren, Linglei Meng, Yuzi Qiu   +9 more
doaj   +1 more source

Paneth Cells Regulate Lymphangiogenesis under Control of Microbial Signals during Experimental Portal Hypertension [PDF]

, 2022
Intestinal microbiota can modulate portal hypertension through the regulation of the intestinal vasculature. We have recently demonstrated that bacterial antigens activate Paneth cells (PCs) to secrete products that regulate angiogenesis and portal ...
Esther Caparrós, Keller, Irene, Witold Wolski, Wolski, Witold, Martínez, Sebastián, Irene Keller, Martínez-López, Sebastián, Paolo Nanni, Nanni, Paolo, Sebastián Martínez-López, Francés, Rubén, Mohsin Hassan, Hassan, Mohsin, Juanola, Oriol, Mohsin, Hassan, Rubén Francés, Moghadamrad, Sheida, Caparrós, Esther, Oriol Juanola, Sheida Moghadamrad   +19 more
core   +1 more source

Risk Factors for Small‐for‐Size Syndrome Grade B/C After Simultaneous Splenectomy in Adult Living‐Donor Liver Transplantation

Annals of Gastroenterological Surgery, EarlyView.
In a single‐center cohort of 577 adult LDLT recipients who underwent simultaneous splenectomy, clinically significant SFSS grade B/C (ILTS‐iLDLT‐LTSI 2023) occurred in 18.2% and was associated with inferior graft survival. Multivariate analysis identified MELD ≥ 30, NLR ≥ 4.5, and donor age ≥ 50 years as independent risk factors, which risk rising ...
Kyohei Yugawa, Takeo Toshima, Shinji Itoh, Takashi Motomura, Shohei Yoshiya, Norifumi Iseda, Tomoharu Yoshizumi   +6 more
wiley   +1 more source