Results 61 to 70 of about 108,295 (308)

Bioengineered Exosome‐Loaded Immunomodulatory Bioadhesive Spray Reverses Liver Fibrosis and Metabolic Dysfunction That Triggers Beneficial Gut‐Liver Crosstalk in Chronic Fatty Liver Disease

open access: yesAdvanced Science, EarlyView.
Umbilical cord stem cell‐derived exosomes encapsulated in an immunomodulatory bioadhesive hydrogel spray enable localized therapy, sustained vesicle delivery, macrophage polarization, suppress systemic inflammation, and mitigate glucose and insulin homeostasis impairments in MAFLD.
Triya Saha   +4 more
wiley   +1 more source

National Consensus on Portal Hypertension Management in Indonesia

open access: yesActa Medica Indonesiana, 2022
Portal hypertension is a clinical syndrome that consists of hypersplenism, ascites, gastroesophageal varices, and encephalopathy. This condition is marked by increased portal pressure gradient and may occur with or without liver cirrhosis.
Juferdy Kurniawan   +7 more
doaj   +2 more sources

Research Progress of Noninvasive Evaluation of Portal Hypertension by Blood‐Based Tests

open access: yesPortal Hypertension & Cirrhosis
Portal hypertension (PH) is a collection of clinical conditions that occur due to an enduring elevation of pressure within the portal venous system, and it is closely linked to the prognosis of liver disease patients. The hepatic venous pressure gradient
Wei Chen   +10 more
doaj   +1 more source

Non-cirrhotic portal fibrosis

open access: yesInternational Journal of Advanced Medical and Health Research, 2014
Portal hypertension occurs commonly in patients with cirrhosis and rarely in those without cirrhosis of liver. The two most important causes of non-cirrhotic portal hypertension are non-cirrhotic portal fibrosis (NCPF) and extrahepatic portal venous ...
Venkatesan Mukta   +2 more
doaj   +1 more source

Difficulties of differential diagnosis of portal hypertension: case report

open access: yesМедицинский совет, 2021
In the article we analysed the difficulties of differential diagnosis of portal hypertension, considers a clinical case that illustrates the presented theoretical material.
T. V. Penkina   +7 more
doaj   +1 more source

Large‐scale Whole‐Exome Sequencing Defines the Protein‐Coding Architecture of Retinal Structure, Visual Function, and Major Blinding Diseases

open access: yesAdvanced Science, EarlyView.
Large‐scale whole‐exome sequencing in 356,982 UK Biobank participants defines the protein‐coding architecture of retinal structure, visual function, and major blinding diseases. Pleiotropic genes, including CFI, C3, and RIOX1, bridge multiple retinal phenotypes, while experimental validation of FYB2 implicates RPE barrier dysfunction, providing ...
Jianqing Li   +23 more
wiley   +1 more source

Whole-course management of interventional treatment in liver cancer patients with portal hypertension

open access: yesJournal of Interventional Medicine, 2019
Primary liver cancer often occurs in patients with hepatitis and cirrhosis. Some patients have portal hypertension due to cirrhosis, and present with varying degrees of collateral circulation, splenomegaly and hypersplenism, ascites, and liver ...
Zhenkang Qiu, Gui Song Wang, Fei Gao
doaj   +1 more source

Hypothalamic Control of Liver Health and Disease: From Circuits to Pathophysiology and Therapies

open access: yesAdvanced Science, EarlyView.
This review delineates the hypothalamic circuits that control liver homeostasis via autonomic and neuroendocrine pathways. Dysregulation of this hypothalamus–liver axis drives disease progression across a spectrum including steatotic liver disease, liver inflammation and injury, fibrosis, cirrhosis, and hepatocellular carcinoma.
Qin Tang   +7 more
wiley   +1 more source

portal hypertension [PDF]

open access: yes, 2004
Portal hypertension is a common syndrome with serious clinical consequences. Some aspects of pathophysiology, causes and clinical features are discussed.
Martinelli, Ana L. Candolo
core   +1 more source

Recent Advances in Functional Liver Volumetry: Emphasis on 99mTc‐GSA SPECT/CT Fusion Imaging

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Functional liver volumetry enables more accurate assessment of the future liver remnant by integrating anatomical and functional information, improving risk stratification before major hepatectomy. Among available techniques, 99mTc‐GSA SPECT/CT fusion imaging enables precise regional functional assessment and more reliable prediction of post ...
Toru Beppu   +4 more
wiley   +1 more source

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