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Varices are a frequent complication of liver cirrhosis and a major cause of mortality in patients with liver cirrhosis. Patients with decompensated cirrhosis complications have a poor prognosis and require careful management.
Min Kyung Park , Yun Bin Lee
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Portal hypertension in cirrhosis: Pathophysiological mechanisms and therapyKey points
Summary: Portal hypertension, defined as increased pressure in the portal vein, develops as a consequence of increased intrahepatic vascular resistance due to the dysregulation of liver sinusoidal endothelial cells (LSECs) and hepatic stellate cells ...
Yasuko Iwakiri, Jonel Trebicka
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AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Background/Aims: Portal hypertension (PH) is a syndrome characterized by chronic increase in the pressure gradient between the portal vein and inferior vena cava. Previous studies have suggested an increased frequency of antral elevated erosive gastritis
Fernanda Cordeiro de Azevedo Conejo +5 more
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Pathophysiology and therapeutic options for cirrhotic portal hypertension. [PDF]
Portal hypertension represents the primary non-neoplastic complication of liver cirrhosis and has life-threatening consequences, such as oesophageal variceal bleeding, ascites, and hepatic encephalopathy.
Guixé-Muntet, Sergi +2 more
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The portal hypertension syndrome: etiology, classification, relevance, and animal models. [PDF]
BACKGROUND Portal hypertension is a key complication of portal hypertension, which is responsible for the development of varices, ascites, bleeding, and hepatic encephalopathy, which, in turn, cause a high mortality and requirement for liver ...
Iwakiri, Yasuko +3 more
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BackgroundCadmium (Cd) accumulates in the body over time, damaging organs such as the liver, kidneys, and brain. Some researchers have suggested that elevated blood Cd levels may contribute to the onset and progression of nonalcoholic fatty liver disease
Congxi Xu +13 more
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Emerging therapies for portal hypertension in cirrhosis.
INTRODUCTION Counteracting splanchnic vasodilatation and increased portal-collateral blood flow has been the mainstay for the treatment of portal hypertension (PH) over the past three decades.
Berzigotti, Annalisa +2 more
core +1 more source
The future treatment of portal hypertension
Increased understanding of the hyperdynamic circulation syndrome has resulted in novel therapeutic approaches, some of which have already reached clinical practice.
Lebrec, Didier, Reichen, Jürg
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Background Skeletal muscle index (SMI) is a commonly used research method for evaluating muscle mass.However, its impact on post-embolization syndrome(PES) of patients with hepatocellular carcinoma (HCC) undergoing transarterial chemoembolization (TACE ...
Xiaojuan Wang +9 more
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