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Pharmacological Therapy of Portal Hypertension [PDF]

open access: yes, 2017
Portal hypertension is a clinical syndrome characterized by pathological elevation of portal venous pressure and all its consequences. In portal hypertension, there is an increase in pressure in the veins that carry blood from the splanchnic organs to ...
Budi Widodo   +11 more
core   +1 more source

Towards a Compositional Framework for Describing Human Phenotypes

open access: yesAdvanced Science, EarlyView.
The Phenotype Assembly Method (PhenoAM) decomposes phenotype variables into measurable Features and typed Qualifiers, enabling standardized, machine‐readable Phenome Data Elements (PhenoDEs) that preserve measurement context. Applied in the International Human Phenome Project (IHPP), the framework yields 58 371 PhenoDEs and supports component‐level ...
Wanting Hu   +11 more
wiley   +1 more source

National Consensus on Portal Hypertension Management in Indonesia

open access: yesActa Medica Indonesiana, 2022
Portal hypertension is a clinical syndrome that consists of hypersplenism, ascites, gastroesophageal varices, and encephalopathy. This condition is marked by increased portal pressure gradient and may occur with or without liver cirrhosis.
Juferdy Kurniawan   +7 more
doaj   +2 more sources

Research Progress of Noninvasive Evaluation of Portal Hypertension by Blood‐Based Tests

open access: yesPortal Hypertension & Cirrhosis
Portal hypertension (PH) is a collection of clinical conditions that occur due to an enduring elevation of pressure within the portal venous system, and it is closely linked to the prognosis of liver disease patients. The hepatic venous pressure gradient
Wei Chen   +10 more
doaj   +1 more source

Non-cirrhotic portal fibrosis

open access: yesInternational Journal of Advanced Medical and Health Research, 2014
Portal hypertension occurs commonly in patients with cirrhosis and rarely in those without cirrhosis of liver. The two most important causes of non-cirrhotic portal hypertension are non-cirrhotic portal fibrosis (NCPF) and extrahepatic portal venous ...
Venkatesan Mukta   +2 more
doaj   +1 more source

Compound Abrus cantoniensis Extract Alleviates AFB1‐Induced Liver Injury by Regulating PI3K‐AKT Pathway and Gut Microbiota/Butyrate Metabolism

open access: yesAdvanced Science, EarlyView.
ACCE has a good alleviating effect on AFB1‐induced liver injury, and this alleviating effect is related to the PI3K‐AKT pathway regulated by ACCE and the butyrate metabolism of gut microbiota. ABSTRACT Aflatoxin B1 (AFB1) is a potent hepatotoxin commonly ingested through contaminated food. Abrus cantoniensis Hance, a traditional Chinese medicinal herb,
Hongjie Hu   +12 more
wiley   +1 more source

Whole-course management of interventional treatment in liver cancer patients with portal hypertension

open access: yesJournal of Interventional Medicine, 2019
Primary liver cancer often occurs in patients with hepatitis and cirrhosis. Some patients have portal hypertension due to cirrhosis, and present with varying degrees of collateral circulation, splenomegaly and hypersplenism, ascites, and liver ...
Zhenkang Qiu, Gui Song Wang, Fei Gao
doaj   +1 more source

Difficulties of differential diagnosis of portal hypertension: case report

open access: yesМедицинский совет, 2021
In the article we analysed the difficulties of differential diagnosis of portal hypertension, considers a clinical case that illustrates the presented theoretical material.
T. V. Penkina   +7 more
doaj   +1 more source

Hepatic microcirculation and mechanisms of portal hypertension.

open access: yes, 2019
The liver microcirculatory milieu, mainly composed of liver sinusoidal endothelial cells (LSECs), hepatic stellate cells (HSCs) and hepatic macrophages, has an essential role in liver homeostasis, including in preserving hepatocyte function, regulating ...
Anabel Fernández-Iglesias   +5 more
core   +1 more source

Emerging Therapeutic Targets for Portal Hypertension. [PDF]

open access: yes, 2023
PURPOSE OF REVIEW Portal hypertension is responsible of the main complications of cirrhosis, which carries a high mortality. Recent treatments have improved prognosis, but this is still far from ideal.
Sonia Selicean   +11 more
core   +2 more sources

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