Results 31 to 40 of about 108,295 (308)
Notch1 signaling in the hepatic microcirculation and chronic liver disease [PDF]
, 2013 The Notch signaling pathway is an evolutionary conserved pathway that plays essential roles during vascular development and in the regulation of normal and pathological angiogenesis in the adulthood.
Rothweiler, Sonja
core +1 more source
Liver and Spleen Stiffness to Predict Portal Hypertension and Its Complications [PDF]
, 2020 Portal hypertension is a common syndrome characterized by an increase in portal venous pressure driving life-threatening complications. In advanced chronic liver disease, increased portal venous pressure is one of the hallmarks of progression; in this ...
Berzigotti, Annalisa +4 more
core +1 more source
Overlooked subclinical portal hypertension in non-cirrhotic NAFLD: Is it real and how to measure it? [PDF]
, 2022 Clinical and experimental advances related to the detection, magnitude and pathobiology of subclinical portal hypertension in non-alcoholic fatty liver disease (NAFLD), primarily observed in the presence of non-alcoholic steatohepatitis (NASH), prompt us
Baffy, Gyorgy, Bosch, Jaime
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Hepatology, EarlyView., 2022 Natural history of liver disease in a large international cohort of children with Alagille syndrome: Results from the GALA study. Abstract Background and Aims Alagille syndrome (ALGS) is a multisystem disorder, characterized by cholestasis. Existing outcome data are largely derived from tertiary centers, and real‐world data are lacking.
Shannon M. Vandriel +93 more
wiley +1 more source
Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis
Hepatology, EarlyView., 2022 Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis. Abstract Background and Aims Nucleotide‐binding oligomerization domain‐like receptor‐family pyrin domain‐containing 3 (NLRP3) inflammasome activation has been shown to result in liver fibrosis.
Jana Knorr +19 more
wiley +1 more source
Annals of Hepatology, 2007 Lipoproteins are synthesized by the liver and secreted to plasma. Chronic alcoholic intoxication produces frequently cirrhosis and concomitantly alterations in liver metabolism.
Abraham Lemberg +8 more
doaj +1 more source
Non-invasive assessment and prediction of clinically significant portal hypertension [PDF]
, 2011 Hepatic venous pressure gradient (HVPG) predicts variceal development, bleeding, clinical decompensation and death. Measurement is invasive, time-consuming and performed in few centres.
Austin, Andrew +7 more
core +1 more source
CD11b+CD43hiLy6Clo splenocyte‐derived macrophages exacerbate liver fibrosis via spleen–liver axis
Hepatology, EarlyView., 2022 A population of splenic monocytes migrate into the liver and shift to macrophages, which account for the exacerbation of liver fibrosis. Abstract Background and Aims Monocyte‐derived macrophages (MoMFs), a dominant population of hepatic macrophages under inflammation, play a crucial role in liver fibrosis progression.
Shaoying Zhang +18 more
wiley +1 more source
Serum bile acids as a prognostic biomarker in biliary atresia following Kasai portoenterostomy
Hepatology, EarlyView., 2022 Serum bile acid levels predict outcomes in patients with biliary atresia who achieve normalized bilirubin levels after Kasai portoenterostomy. Abstract Background and Aims In biliary atresia, serum bilirubin is commonly used to predict outcomes after Kasai portoenterostomy (KP).
Sanjiv Harpavat +22 more
wiley +1 more source
Acute deterioration of idiopathic portal hypertension requiring living donor liver transplantation: a case report. [PDF]
, 2009 Case reports of severe idiopathic portal hypertension (IPH) requiring liver transplantation are very rare. We report the case of a 65-year-old woman who was diagnosed as having IPH.
Yoshitsugu Tajima +23 more
core +1 more source