Results 91 to 100 of about 2,394,283 (349)

Avoidable Hospitalizations in Persons With Rheumatoid Arthritis: A Population‐Based Study Using Administrative Data

open access: yesArthritis Care &Research, EarlyView.
Objective We estimated incidence rates of avoidable hospitalizations by persons with rheumatoid arthritis (RA) relative to the general population. Methods We identified individuals meeting a validated case definition for RA based on International Classification of Diseases, Ninth Revision, Clinical Modification (ICD‐9‐CM) and ICD‐10‐CA codes in years ...
Dani G. Contreras   +6 more
wiley   +1 more source

Right Ventricular Remodeling and Dysfunction in Obstructive Sleep Apnea: A Systematic Review of the Literature and Meta-Analysis

open access: yesCanadian Respiratory Journal, 2017
Background. Recent studies have reported that obstructive sleep apnea (OSA) patients present alterations in right ventricular (RV) structure and function. However, large randomized controlled trials evaluating the impact of OSA on the right ventricle are
Abdirashit Maripov   +8 more
doaj   +1 more source

Nitric oxide activates AMPK by modulating PDE3A in human pulmonary artery smooth muscle cells

open access: yesPhysiological Reports, 2020
Phosphodiesterase 3 (PDE3), of which there are two isoforms, PDE3A and PDE3B, hydrolyzes cAMP and cGMP—cyclic nucleotides important in the regulation of pulmonary vascular tone.
Julie Dillard   +4 more
doaj   +1 more source

Pathogenic Role of mTORC1 and mTORC2 in Pulmonary Hypertension. [PDF]

open access: yes, 2018
Concentric lung vascular wall thickening due to enhanced proliferation of pulmonary arterial smooth muscle cells is an important pathological cause for the elevated pulmonary vascular resistance reported in patients with pulmonary arterial hypertension ...
Ayon, Ramon J   +18 more
core   +1 more source

Care of patients with pulmonary arterial hypertension during the coronavirus (COVID-19) pandemic

open access: yesPulmonary Circulation, 2020
The COVID-19 pandemic presents many unique challenges when caring for patients with pulmonary hypertension. The COVID-19 pandemic has altered routine standard of care practice and the acute management particularly for those patients with pulmonary ...
J. Ryan   +6 more
semanticscholar   +1 more source

Extracorporeal Catalytic Hemoperfusion Therapy for Refractory Septic Shock Using Ceria Nanoparticle‐Embedded Porous Microbeads

open access: yesAdvanced Functional Materials, EarlyView.
This study introduces an extracorporeal hemoperfusion system incorporating porous microbeads embedded with autocatalytic ceria nanoparticles (CeNPs) for targeted reactive oxygen species (ROS) scavenging in septic shock. The blood‐compatible hemoperfusion cartridge demonstrated significant improvements in survival, hemodynamic stability, and organ ...
Pilseon Im   +10 more
wiley   +1 more source

Noninvasive Estimation of Mean Pulmonary Artery Pressure Using MRI, Computer Models, and Machine Learning [PDF]

open access: yesarXiv, 2023
Pulmonary Hypertension (PH) is a severe disease characterized by an elevated pulmonary artery pressure. The gold standard for PH diagnosis is measurement of mean Pulmonary Artery Pressure (mPAP) during an invasive Right Heart Catheterization. In this paper, we investigate noninvasive approach to PH detection utilizing Magnetic Resonance Imaging ...
arxiv  

Cardiac sympathetic dysfunction in pulmonary arterial hypertension: Lesson from left-sided heart failure [PDF]

open access: yes, 2019
Sympathetic nervous system hyperactivity has a well-recognized role in the pathophysiology of heart failure with reduced left ventricular ejection fraction.
Bonaduce, Domenico   +10 more
core   +1 more source

An overview of the 6th World Symposium on Pulmonary Hypertension

open access: yesEuropean Respiratory Journal, 2019
Since 1973 the World Symposia on Pulmonary Hypertension (WSPH) proceedings have summarised the scientific advances and future needs in this field through the efforts of multiple task forces, each focusing on a different aspect of pulmonary hypertension ...
N. Galiè   +3 more
semanticscholar   +1 more source

Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations

open access: yesAdvanced Functional Materials, EarlyView.
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan   +4 more
wiley   +1 more source

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